Author: Stephen J. Simko

0000000000041166

AUTHOR

Stephen J. Simko

0000-0002-4790-4117

BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.

BRAF-V600E expression is identified in hematopoietic progenitor and precursor myeloid dendritic cells in patients with high-risk LCH, and enforced expression of BRAF-V600E in CD11c+ cells recapitulates a high-risk LCH-like phenotype in mice.

research product

PEPhysical Sciences and Engineering
- PE2Fundamental Constituents of Matter
  - PE2_1Theory of fundamental interactions
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  - PE2_10Atomic, molecular physics
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- PE1Mathematics
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  - PE1_4 Algebraic and complex geometry
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LSLife Sciences
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- LS5Neuroscience and Disorders of the Nervous System
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SHSocial Sciences and Humanities
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