0000000000041562

AUTHOR

Deniz Demir

showing 2 related works from this author

Rugged Large Volume Injection for Sensitive Capillary LC-MS Environmental Monitoring

2017

A rugged and high throughput capillary column (cLC) LC-MS switching platform using large volume injection and on-line automatic filtration and filter back-flush (AFFL) solid phase extraction (SPE) for analysis of environmental water samples with minimal sample preparation is presented. Although narrow columns and on-line sample preparation are used in the platform, high ruggedness is achieved e.g. injection of 100 non-filtrated water samples would did not result in a pressure rise/clogging of the SPE/capillary columns (inner diameter 300 µm). In addition, satisfactory retention time stability and chromatographic resolution were also features of the system. The potential of the platform for …

Resolution (mass spectrometry)Capillary actionAnalytical chemistry02 engineering and technologycapillary LC01 natural scienceslaw.inventionlcsh:ChemistrylawLiquid chromatography–mass spectrometrySample preparationSolid phase extractionon-line solid phase extractionFiltrationOriginal ResearchDetection limitChromatographyChemistry010401 analytical chemistryGeneral ChemistryRepeatability021001 nanoscience & nanotechnology0104 chemical sciencespharmaceutical productsChemistrylcsh:QD1-999column switchinglarge volume injection0210 nano-technologyFrontiers in Chemistry
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Central corneal thickness in mucopolysaccharidosis II and VI.

2010

Objective To describe the ultrasonographically detected central corneal thickness (CCT) in patients with Type II and VI mucopolysaccharidosis (MPS) and its impact on applanation tonometry and glaucoma detection. Methods Twenty-eight patients with MPS (19 MPS II, nine MPS VI) underwent pachymetric investigation of CCT. Additionally, ultrasound measurements of axial length of the globe, slit-lamp evaluation with semiquantitative grading of corneal clouding, applanation tonometry, and assessment of refractive error were performed. Results Median average corneal thickness was 534.5 microm (range, 491.5-579.0 microm) in the MPS II and 547.0 microm (range, 492.5-693.05 microm) in the MPS VI group…

Applanation tonometryAdultMalecongenital hereditary and neonatal diseases and abnormalitiesRefractive errorIntraocular pressuremedicine.medical_specialtygenetic structuresAdolescentMucopolysaccharidosis IIMucopolysaccharidosisGlaucomaCorneal DiseasesCorneaTonometry OcularOphthalmologymedicineHumansIn patientProspective StudiesChildIntraocular PressureMucopolysaccharidosis IIUltrasonographyMucopolysaccharidosis VIAnthropometrybusiness.industryUltrasoundnutritional and metabolic diseasesGlaucomaMiddle Agedmedicine.diseaseeye diseasesOphthalmologyFemalesense organsbusinessCornea
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