0000000000042564

AUTHOR

ŁUkasz Kruszyna

0000-0001-5205-5765

showing 3 related works from this author

The Expression and Prognostic Significance of VEGF and CXCR4 in Gastric Cancer: Correlation with Angiogenesis, Lymphangiogenesis and Progression

2022

The cellular response to hypoxia includes the expression of hypoxia-inducible factor-1 (HIF-1) and its target genes: vascular endothelial growth factor (VEGF) and CXC chemokine receptor 4 (CXCR4). The aim of this study was to investigate the expression and prognostic significance of VEGF and CXCR4, which are responsible for angiogenesis and progression in gastric cancer. Twenty-eight gastric cancer patients were analyzed. The mRNA expression was examined in primary tumors and corresponding normal gastric mucosa by RT-PCR. The protein level was examined by immunohistochemistry staining. The high expression of VEGF and CXCR4 was found in 71.0 and 64.0% of tumors, respectively. The mean levels…

Microbiology (medical)gastric cancer; VEGF; CXCR4; angiogenesis; lymphangiogenesis; lymph node metastasesGeneral MedicineMolecular BiologyMicrobiologyCurrent Issues in Molecular Biology
researchProduct

Midterm Results of the Treatment of Penetrating Abdominal Aortic or Iliac Artery Ulcer with the BeGraft Balloon-Expandable Covered Stent-A Single-Cen…

2020

Background The purpose of the study was to evaluate the feasibility and efficacy of the novel BeGraft covered stent for the treatment of abdominal penetrating aortic ulcer (PAU) or penetrating ulcers of the iliac arteries (PUIAs). Methods This was a single-center observational study, which included 24 consecutive patients who underwent endovascular surgery due to abdominal PAU or PUIA between June 2017 and September 2019. Demographics of patients, lesion characteristics, diameter and length of the BeGraft stents, and postoperative events were prospectively collected and retrospectively analyzed. Follow-up examinations were performed at 1, 6, 12, and 24 months with clinical and hemodynamic e…

AdultMalemedicine.medical_specialtyTime FactorsAortic DiseasesHemodynamics030204 cardiovascular system & hematologySingle CenterIliac Artery030218 nuclear medicine & medical imagingLesion03 medical and health sciencesPseudoaneurysm0302 clinical medicinemedicine.arterymedicineHumansAorta AbdominalElective surgeryCovered stentUlcerAgedRetrospective StudiesAged 80 and overbusiness.industryGeneral MedicinePerioperativeMiddle Agedmedicine.diseaseCommon iliac arterySurgeryTreatment OutcomeFeasibility StudiesSurgeryFemaleStentsPolandmedicine.symptomCardiology and Cardiovascular MedicinebusinessAngioplasty BalloonAnnals of vascular surgery
researchProduct

The intravascular ultrasound morphometry of iliac veins in subjects without severe chronic venous insufficiency and its implications for treatment in…

2019

Objectives The purpose of this study is to report the intravascular ultrasound morphometry of iliac veins and its relation to demographic and anthropometric factors in subjects without chronic venous insufficiency. Methods Thirty-three patients, without chronic venous insufficiency – qualified to great saphenous vein stripping due to unilateral, primary varicose veins – participated in the study. During the surgery, left and right external iliac veins, common iliac veins and inferior vena cava were interrogated with intravascular ultrasound. The morphometric analysis included measurement of a cross-sectional area at normal, non-stenosed vein segments (ref-CSA) and at the point of the most p…

AdultMalemedicine.medical_specialtyChronic venous insufficiencymedicine.medical_treatmentClinical Decision-MakingVena Cava InferiorConstriction Pathologic030204 cardiovascular system & hematologyIliac Vein030218 nuclear medicine & medical imagingVaricose Veins03 medical and health sciencesYoung Adult0302 clinical medicinePredictive Value of TestsIntravascular ultrasoundmedicineHumansSaphenous VeinLigationSelection (genetic algorithm)Ultrasonography InterventionalAgedPeripheral Vascular Diseasesmedicine.diagnostic_testbusiness.industryEndovascular ProceduresStentGeneral MedicineMiddle Agedmedicine.diseaseIliac veinscardiovascular systemiliac veins morphometryFemaleStentsIntravascular ultrasoundRadiologyCardiology and Cardiovascular MedicinebusinessVascular Surgical ProceduresPhlebology
researchProduct