0000000000046975

AUTHOR

Francisco O'valle

showing 3 related works from this author

Marginal Bone Loss in Implants Placed in Grafted Maxillary Sinus

2013

Purpose The purpose of this study is to evaluate the vertical and horizontal graft bone resorption (GR) in grafted maxillary sinuses and the marginal bone loss (MBL) around implants placed in the sinuses with different prosthetic connections and to determine the effect of other clinical factors on these tissue responses at 6 and 18 months postloading. Material and Method A total of 254 implants were placed in 150 grafted maxillary sinuses of 101 patients (51.5% female) with mean age of 52.2 years (range, 32–82 years). GR and MBL measurements were made in implants placed with two different prosthetic connections (internal and external) at 6 and 18 months postloading. The complex samples gene…

Maxillary sinusbusiness.industryDentistryBone resorptionResorptionmedicine.anatomical_structureMedicineCortical boneImplantOral SurgerybusinessGeneral DentistryAbutment (dentistry)Sinus (anatomy)Dental alveolusClinical Implant Dentistry and Related Research
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Association between COX-2 rs 6681231 genotype and interleukin-6 in periodontal connective tissue. A pilot study.

2014

[Objectives] The aim of this pilot study was to investigate associations between IL-6 and COX-2 expression in gingival biopsies and both clinical diagnosis and genotypes in the IL-6 and COX-2 genes. [Design] A case-control study included 41 gingival biopsies obtained from Caucasian patients grouped according to clinical diagnosis of gingival health (n = 10), gingivitis (n = 15) or chronic periodontitis (n = 16). Immunohistochemistry analyses were performed to determine COX-2 expression in lamina propria, IL-6 expression in lamina propria and gingival epithelium and level of inflammatory cell infiltrate. Individual DNA was extracted and genotyped by real-time PCR for IL6 SNPs rs 2069827 and …

Bacterial DiseasesMaleBiopsyGingivaDentistryGene ExpressionPilot ProjectsEpitheliumMonocytesGingivitisGenotypehealth care economics and organizationsPlasma cellsMultidisciplinaryGingival AbscessesbiologyQRMiddle AgedGingivitishumanitiesmedicine.anatomical_structureInfectious DiseasesCOX-2 6681231 genotype interleukin-6 periodontitisCytokinesPeriodontal AbscessesMedicineFemalemedicine.symptomPeriodontal IndexConnective tissueImmunohistochemical AnalysisResearch ArticleAdultmedicine.medical_specialtyClinical Research DesignScienceOral MedicineConnective tissueHemorrhagePolymorphism Single NucleotideInternal medicinemedicineGeneticsHumansInterleukin 6PeriodontitisBiologyAgedPeriodontitisClinical GeneticsInflammationbusiness.industryInterleukin-6Case-control studymedicine.diseaseChronic periodontitisHaplotypesCyclooxygenase 2Immune SystemCase-Control StudiesChronic Periodontitisbiology.proteinGenetic PolymorphismImmunologic TechniquesClinical ImmunologybusinessPopulation GeneticsPLoS ONE
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Heat-shock protein 60 kDa and atherogenic dyslipidemia in patients with untreated mild periodontitis: a pilot study

2012

Identification of predictors of cardiovascular risk can help in the prevention of pathologic episodes and the management of patients at all stages of illness. Here, we investigated the relationships between serum levels of Hsp60 and dyslipidemia in patients with periodontitis by performing a cross-sectional study of 22 patients with mild periodontitis without any prior treatment for it (i.e., drug naive) and 22 healthy controls, matched for age and body mass index (BMI). All subjects were evaluated for periodontal status, gingival inflammation, and oral hygiene. Levels of circulating Hsp60, C-reactive protein (CRP), and plasma lipids were measured, and small, dense low-density lipoproteins …

AdultMalemedicine.medical_specialtyPeriodontal pathologyPilot ProjectsBiochemistryBody Mass Indexchemistry.chemical_compoundRisk FactorsInternal medicinemedicineHumansperiodontitisTriglyceridesDyslipidemiasPeriodontitisOriginal PaperbiologyCholesterolbusiness.industrydyslipidemiaC-reactive proteinAge FactorsMouth MucosaChaperonin 60Cell BiologyMiddle AgedHsp60medicine.diseaseLipidsHsp60; dyslipidemia; periodontitisLipoproteins LDLDrug-naïveC-Reactive ProteinCross-Sectional StudiesEndocrinologychemistryCardiovascular Diseasesbiology.proteinFemaleMetabolic syndromeLipoproteins HDLbusinessBody mass indexDyslipidemiamedicine.drugCell Stress and Chaperones
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