0000000000048265
AUTHOR
José Blanquer
Severe Sepsis Due To Community-acquired Pneumonia (CAP) In Population Under Age 65
Validation Of Ecurb In Community-Acquired Pneumonia: Which Gold Standard Are We Talking About?
Accuracy Of Non-Invasive Methods For The Evaluation Of Oxygenation Status In Community-Acquired Pneumonia: Comparison Of PaO2/FiO2 Calculated From Severinghaus And Rice Equations
Less Is More: Different Weight of the ATS/IDSA'07 Minor Criteria on Mortality Prediction in Severe Pneumonia (SCAP).
Outpatient Treatment And Community Acquired Pneumonia (CAP): A Comparative Study With Hospital Admission
Epigenetics As The Driving Force In Long-Term Immunosuppression
Epigenetics is an emerging frontier of biology, with the potential for deciphering the intricate molecular and transcriptional cellular programs, therefore contributing to explain the pathological evolution of sepsis, one of the most elusive syndromes in medicine. The evolution of sepsis depends not only on the pathogen which originated the infection but also on the genetic and epigenetic background of the host. Short-term mortality of sepsis and septic shock is high, being considered a public health concern worldwide. Immunosuppression is the predominant driving force for morbidity and mortality in late deaths and long-term deaths of survivors from a sepsis episode. In this regard, apoptos…
Differences between Community Acquired Legionnaire's Pneumonia (CAP-L) and Pneumococcal Pneumonia (CAP-P).
Should Broad-Spectrum Antibiotic Be Recommended For Pneumococcal Health-Care Associated Pneumonia?
Varicella-zoster Virus Pneumonia In An Adult Population. Has The Pattern Of Mortality Been Changed?
Community Acquired Pneumonia (CAP) With PSI V Admitted To Intensive Care Unit (ICU). Comparative Study
Phenotypic Characteristics And Outcomes Of Early Pneumonia Diagnosis (within 24 Hours)
Long-term Prognostic Value Of CURB-65 In Community-acquired Pneumonia
Differential Features Of Community Acquired Pneumonia (CAP) In Young Adults
Hypoxemia Adds to the CURB-65 Pneumonia Severity Score in Hospitalized Patients With Mild Pneumonia
BACKGROUND: Hypoxemia may influence the prognosis of patients with mild pneumonia, regardless of the initial CURB-65 score (confusion, blood urea nitrogen > 20 mg/dL, respiratory rate > 30 breaths/min, blood pressure < 90/60 mm Hg, and age ≥ 65 y). OBJECTIVE: To determine the risk factors associated with hypoxemia and the influence of hypoxemia on clinical outcomes in hospitalized patients with mild pneumonia. METHODS: We performed a multicenter prospective cohort study of 585 consecutive hospitalized patients with mild pneumonia (CURB-65 groups 0 and 1). We stratified the patients according to the presence of hypoxemia, defined as a PaO2/FIO2 < 300 mm Hg on admission. We assessed the risk …
Assessment of Analysis of Urinary Pneumococcal Antigen by Immunochromatography for Etiologic Diagnosis of Community-Acquired Pneumonia in Adults
ABSTRACT The limitations of conventional microbiologic methods (CMM) for etiologic diagnosis of community pneumococcal pneumonia have made faster diagnostic techniques necessary. Our aim was to evaluate the usefulness of the immunochromatography (ICT) technique for detecting urinary Streptococcus pneumoniae antigen in the etiologic diagnosis of community-acquired pneumonias (CAP). This was a prospective study on in-patients with CAP in a tertiary hospital conducted from October 2000 to March 2004. Apart from using CMM to reach an etiologic diagnosis, we determined pneumococcal antigen in concentrated urine by ICT. We also determined the urinary pneumococcal antigen (UPA) content in patients…
Antibiotic Use Prior To Admission And Community Acquired Pneumonia (CAP)
Is it possible to predict which patients with mild pneumonias will develop hypoxemia?
SummaryUsually, mortality due to mild community-acquired pneumonias (CAP) (Pneumonia severity index (PSI) classes I–III) is low (<3%), but the appearance of hypoxemia significantly increases mortality. Our aim was to determine the clinical parameters associated with risk factors of developing hypoxemia in subjects with mild CAP (PSI I–III) and the clinical outcomes of the hypoxemic group.We analyzed clinical characteristics and the outcomes of patients with mild CAP and hypoxemia (PaO2/FiO2<300), in a prospective, multicenter cohort study of 1195 patients.Mild pneumonias (PSI I–III) were found in 645 cases (53.9%), of which 217 (33.6%) presented hypoxemia according to a PaO2/FiO2<300. Patie…