Severe Sepsis Due To Community-acquired Pneumonia (CAP) In Population Under Age 65

Validation Of Ecurb In Community-Acquired Pneumonia: Which Gold Standard Are We Talking About?

Accuracy Of Non-Invasive Methods For The Evaluation Of Oxygenation Status In Community-Acquired Pneumonia: Comparison Of PaO2/FiO2 Calculated From Severinghaus And Rice Equations

Is Cap Etioloy Inluenced By Climate And Seasonality?

LSC Abstract – Increased oxidative stress leads to telomere shortening in children with alpha-1 antitrypsin deficiency

Background: Oxidative stress (OS) is involved in the pathophysiology of AATD (Escribano A. et al. Thorax 2015; 70:82-3). In addition, it has been shown that OS accelerates telomere shortening which is associated to higher emphysema risk in COPD patients. Rationale and aims: Since AATD is characterised by chronic OS, we hypothesise that telomere shortening would be accelerated in AATD patients and would be associated with higher risk of developing lung disease. This study is aimed to assess the OS profile, the enzymatic antioxidant defence mechanisms and telomere length (TL) in children with AATD and to study its association with AAT phenotypes. Methods: OS parameters, the activity of the ma…

Asthma and influenza vaccination in elderly hospitalized patients: Matched case-control study in Spain

Influenza infection is an exacerbating factor for asthma, and its prevention is critical in managing asthmatic patients. We investigated the effect of influenza vaccination on asthmatic and non-asthmatic patients hospitalized with laboratory-confirmed influenza in Spain.We made a matched case-control study to assess the frequency of hospitalization for influenza in people aged ≥65 years. Hospitalized patients with unplanned hospital admissions were recruited from 20 hospitals representing seven Spanish regions. Cases were defined as those hospitalized due to a laboratory-confirmed influenza infection and controls were matched by age, sex, and hospital. Data were obtained from clinical recor…

Outpatient Treatment And Community Acquired Pneumonia (CAP): A Comparative Study With Hospital Admission

Differences between Community Acquired Legionnaire's Pneumonia (CAP-L) and Pneumococcal Pneumonia (CAP-P).

The potential role of 13-valent pneumococcal conjugate vaccine in preventing respiratory complications in bacteraemic pneumococcal community-acquired pneumonia.

Abstract Introduction Pneumococcal 13-valent vaccine (PCV-13) has a potential role in preventing bacteraemic pneumococcal pneumonia and its complications, but little is known about its ability to specifically prevent respiratory complications. Our aim were to analyse the pneumococcal serotypes associated with the development of respiratory complications and the potential role of PCV-13 in preventing respiratory complications in bacteraemic pneumococcal pneumonia. Material and methods We analysed demographic characteristics, comorbidities, antibiotic resistances and the outcomes of a cohort of 65 vaccine-naive bacteraemic pneumococcal pneumonias, stratified by the pneumococcal serotypes incl…

Should Broad-Spectrum Antibiotic Be Recommended For Pneumococcal Health-Care Associated Pneumonia?

Varicella-zoster Virus Pneumonia In An Adult Population. Has The Pattern Of Mortality Been Changed?

Community Acquired Pneumonia (CAP) With PSI V Admitted To Intensive Care Unit (ICU). Comparative Study

Spanish Version Of The Sleep Apnoea Quality Of Life Index (SAQLI)

Phenotypic Characteristics And Outcomes Of Early Pneumonia Diagnosis (within 24 Hours)

Long-term Prognostic Value Of CURB-65 In Community-acquired Pneumonia

Differential Features Of Community Acquired Pneumonia (CAP) In Young Adults

Is It Important To Correlate HRCT Visual Score With Pulmonary Function Tests (PFT) In IPF Patients?

Antisynthetase syndrome (AS) in patients with diffuse interstitial lung disease (ILD)

Objectives: To determine the prevalence of SAS in patients with ILD and its clinical characteristics, evolution and specific manifestations linked to each antisynthetase antibodies and highlight the need for its screening in ILD. Methods: Retrospective analysis of patients registered in the last two years in our ILD unit, determining antisynthetase antibodies and analyzing clinical, radiological, functional data and illness evolution. Results: 119 ILD patients were included, 10.9% had antisynthetase antibodies, the most prevalent were Jo-1 (46.1%) and PL-12 (38.5%). In PL-12 patients inicial and respiratory syntoms were predominant, whereas in the Jo-1 patients were more frequent extrapulmo…

Spanish Version Of The Quebec Sleep Questionnaire (QSQ)

Antibiotic Use Prior To Admission And Community Acquired Pneumonia (CAP)

Accelerated telomere attrition in children and teenagers with α1-antitrypsin deficiency.

Numerous studies have shown that oxidative stress accelerates telomere shortening in several lung pathologies. Since oxidative stress is involved in the pathophysiology of α1-antitrypsin deficiency (AATD), we hypothesised that telomere shortening would be accelerated in AATD patients. This study aimed to assess telomere length in AATD patients and to study its association with α1-antitrypsin phenotypes.Telomere length, telomerase activity, telomerase reverse transcriptase (hTERT) expression and biomarkers of oxidative stress were measured in 62 children and teenagers (aged 2–18 years) diagnosed with AATD and 18 controls (aged 3–16 years).Our results show that intermediate-risk (MZ; SZ) and …

WHY LOW RISK COMMUNITTY ACQUIRED PNEUMONIA (PSI I-III) ARE ADMITTED TO ICU?

CHARACTERISTICS OF COMMUNITTY ACQUIRED PNEUMONIA IN VERY ELDERLY PATIENTS

Benefit of using an age-adjusted D-dimer cut-off

Introduction: The association between a low-moderate pretest clinical probability and a negative D-dimer (DD) value is able to exclude the possibility of pulmonary embolism (PE). The value of DD seems to increase with age, reducing its specificity. Therefore, we intend to evaluate the usefulness of an age-adjusted cut-off value for age above 50 years, applying the formula suggested by Douma (age*10) set to our laboratory method (age*5) (1) . Patients and Methods: Observational, retrospective study from January to December 2011. DD test were performed to 1515 patients attended in the emergency room of our hospital according to the clinical suspicion made by the doctor who evaluated them. The…

LSC Abstract – Oxidative stress in nasal epithelial cells from patients with primary ciliary dyskinesia

Background: Primary ciliary dyskinesia (PCD) is a rare autosomal recessive inheritance disorder characterized by dysfunction of respiratory cilia and impaired mucociliary clearance, leading to respiratory problems appearing in childhood, decreased fertility and situs inversus in 50% of the cases. The deficient ciliary movement causes stasis of secretions in the airways leading to recurrent airway infection and chronic inflammation. Rationale and aims: Chronic inflammation has been associated to oxidative stress (OS). Moreover, evidence of increased OS in the airways of stable children with PCD has been shown (Zihlif, N. et al . Pediatr Pulmonol 2006; 41:509-14.). Therefore, we hypothesize t…