Author: M Amparo Martínez-gómez

0000000000052130

AUTHOR

M Amparo Martínez-gómez

showing 2 related works from this author

Supplemental material for Quantitative and qualitative control of antineoplastic preparations: Gravimetry versus HPLC

2019

Supplemental Material for Quantitative and qualitative control of antineoplastic preparations: Gravimetry versus HPLC by Ana Sendra-García, M Amparo Martínez-Gómez, Asunción Albert-Marí, N Victor Jiménez-Torres and Mónica Climente-Martí in Journal of Oncology Pharmacy Practice

FOS: Clinical medicine111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified111299 Oncology and Carcinogenesis not elsewhere classified

researchProduct

Quantitative and qualitative control of antineoplastic preparations: Gravimetry versus HPLC.

2019

This article compares gravimetry vs. high-performance liquid chromatography (HPLC) as quality control (QC) methods for paclitaxel, docetaxel and oxaliplatin preparations. We aimed at assessing the preparation method reliability in our hospital, evaluating compounding accuracy and estimating the influence of personnel training and standardized homogenization on compounding accuracy. Agreement, correlation, concordance, accuracy and precision between methods were evaluated for each drug. Conforming preparation percentages (CPs) at different tolerance limits (TLs) and compounding accuracy were calculated for each method and drug. Compounding accuracy was compared before and after personnel tra…

Quality ControlAccuracy and precisionPaclitaxelCytostatic agentsAntineoplastic AgentsDocetaxelHigh-performance liquid chromatographyPreparation method03 medical and health sciences0302 clinical medicineMedicineHumansPharmacology (medical)GravimetryChromatography High Pressure LiquidDrug compoundingChromatographybusiness.industryReproducibility of ResultsOncologyDocetaxelCompounding030220 oncology & carcinogenesisbusiness030215 immunologymedicine.drugJournal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

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