0000000000052855
AUTHOR
Maurizio Castelli
showing 5 related works from this author
Excess risk of subsequent malignant neoplasms in adolescent and young adult cancer survivors: Results from the first Italian population-based cohort
2022
Background: Evidence about late effects in adolescent and young adult (AYA) cancer survivors is scarce. This study assessed the risk of subsequent malignant neoplasms (SMNs) to identify the most common SMNs to be considered in follow-up care. Methods: Population-based cancer registries retrospectively identified first primary tumors (between 1976 and 2013) and SMNs in AYAs (15-39 years old at their cancer diagnosis). AYA cancer survivors were those alive at least 5 years after their first cancer diagnosis. The excess risk of SMNs was measured as standardized incidence ratios (SIRs) and absolute excess risk together with the cumulative incidence of SMNs. Results: The cohort included 67,692 A…
Adolescent and Young Adult Cancer Survivors: Design and Characteristics of the First Nationwide Population-Based Cohort in Italy
2020
Purpose: Adolescent and young adult (AYA, 15-39 years) cancer survivors (alive at least 5 years after cancer diagnosis) are less studied than younger and older cancer survivors and research on their late effects is limited. To facilitate research on long-term outcomes of AYA cancer survivors, we established, in Italy, a population-based AYA cancer survivors' cohort. This article describes the study design and main characteristics of this cohort. Methods: The cohort derives from population-based cancer registries (CRs). Each CR identified AYA cancer patients retrospectively. Treatment for first primary cancer and all health events from diagnosis to death can be traced through linkage with av…
Cancer registries and data protection in the age of health digital interoperability in Europe: The perspective of the Italian Network of Cancer Regis…
2022
Population-based cancer registries (PBCRs) are advanced public health systems providing ongoing surveillance through systematic collection, analysis, interpretation, and dissemination of high-quality data on cancer incident cases registered in a defined population residing in a specific geographical area (1, 2). Basically, PBCRs are well equipped for strengthening cancer surveillance, playing a strategic role in making geographic and temporal variation comparisons to highlight cancer epidemics, while assessing the effectiveness of preventive interventions and oncological care (3). Furthermore, many PBCRs provide cancer risk communication to local communities and authorities by using valuabl…
Effects of grazing on welfare and production traits of organic dairy cows
2013
In organic livestock systems, grazing is the preferred feeding source, especially for animal welfare and health implications, but it is not an obliged practice. In order to contribute on this topic, in an organic dairy farm, grazing was compared with permanent free-stall housing using two homogeneous groups of eight Bruna cows allocated to the following regimes: (G) grazing on barley grass for 5 h/d, and then kept in a free-stall structure and fed with unifeed, composed of hay and concentrate; (S) kept in a free-stall building for 24 h/d and fed with a diet based on the same unifeed. Comparison was based on milk production, behaviour, immune responses, metabolic status and oxidative stress …