0000000000053183

AUTHOR

Freya Trautmann

showing 3 related works from this author

Occupational UV-Exposure is a Major Risk Factor for Basal Cell Carcinoma

2017

The aim of this study was to investigate the role of occupational and nonoccupational ultraviolet (UV)-exposure concerning the development of basal cell carcinoma (BCC).We undertook a population-based multicenter case-control study. Patients with first incident BCC (n = 836) were propensity score matched by age and sex to controls without skin cancer (n = 836). Sociodemographic characteristics, clinical characteristics, and lifetime UV-exposure were assessed by trained investigators. The differential estimation of occupational and nonoccupational UV-exposure dosages was based on validated instruments and established reference values. Associations were assessed using multivariable-adjusted c…

AdultMaleOncologymedicine.medical_specialtySkin NeoplasmsUltraviolet RaysPopulationPopulation basedRadiation Dosage030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineRisk FactorsOccupational ExposureInternal medicineOdds RatiomedicineCarcinomaHumansBasal cell carcinomaRisk factorPropensity Scoreskin and connective tissue diseaseseducationAgedAged 80 and overeducation.field_of_studyintegumentary systembusiness.industryfungiPublic Health Environmental and Occupational HealthCase-control studyDose-Response Relationship RadiationOdds ratioMiddle Agedmedicine.diseaseMulticenter studyCarcinoma Basal CellCase-Control Studies030220 oncology & carcinogenesisFemalebusinessJournal of Occupational & Environmental Medicine
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Patients with soft tissue sarcoma comprise a higher probability of comorbidities than cancer-free individuals. A secondary data analysis.

2016

Soft tissue sarcoma comprises a heterogeneous group of solid malignant tumours. Comorbidities are important prognostic factors for survival and adversely impact quality of life. We examined the complex relationship between soft tissue sarcoma and comorbidities over time in a large population-based sample. The study uses routine data from the German statutory healthcare system (n = 2,615,865). Case identification of soft tissue sarcoma and comorbid diseases was based on ICD-10 codes and diagnostic modifiers. Uni- and multivariate regression models were used to obtain risk estimates for chronic somatic and mental comorbidities in soft tissue sarcoma patients compared to a cancer-free control …

AdultMalemedicine.medical_specialtyAdolescentAdjustment disordersSoft Tissue NeoplasmsComorbidityAngina03 medical and health sciencesYoung Adult0302 clinical medicineRisk FactorsInternal medicineGermanymedicinePrevalenceHumans030212 general & internal medicineRisk factorChildDepression (differential diagnoses)AgedAged 80 and overbusiness.industrySoft tissue sarcomaInfantSarcomaMiddle Agedmedicine.diseaseComorbiditySurgeryOncology030220 oncology & carcinogenesisChild PreschoolRegression AnalysisFemaleSarcomabusinessAnxiety disorderEuropean journal of cancer care
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Is ultraviolet exposure acquired at work the most important risk factor for cutaneous squamous cell carcinoma? Results of the population-based case-c…

2018

Background Squamous cell carcinoma (SCC) is among the most frequent types of cancer constituting a significant public health burden. Prevention strategies focus on limiting UV-exposure during leisure time. However, the relative impact of occupational and non-occupational UV-exposure for SCC occurrence is unclear. Objectives To investigate the association between occupational and non-occupational UV-exposure with SCC in a multicenter population-based case-control study hypothesizing that high occupational UV-exposure increases the risk for SCC. Methods Consecutive patients with incident SCC (n=632) were recruited from a German national dermatology network. Population-based controls (n=996) w…

AdultMalemedicine.medical_specialtyPercentileNeoplasms Radiation-InducedSkin NeoplasmsUltraviolet RaysPopulationDermatology030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineRisk FactorsGermanyInternal medicinePrevalencemedicineHumansRisk factoreducationAgededucation.field_of_studybusiness.industryIncidenceIncidence (epidemiology)Case-control studyDose-Response Relationship RadiationEnvironmental ExposureOdds ratioMiddle Agedmedicine.diseaseSurgeryOccupational DiseasesCase-Control Studies030220 oncology & carcinogenesisPropensity score matchingCarcinoma Squamous CellFemaleSkin cancerbusinessBritish Journal of Dermatology
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