0000000000054918
AUTHOR
I. Lombardo
The aristaless (Arx) gene: one gene for many "interneuronopathies".
The ARX (Aristaless-related (X-linked) homeobox) gene is not only present in arthropods and their ancestors, but also in vertebrates including humans (ARX orthologs). The gene is composed of 5 coding exons and it is expressed predominantly in foetal and adult brain and skeletal muscle. In this review we report on our experience and review the existing literature on the genotype and phenotype heterogeneity associated with ARX abnormalities in humans ranging from severe neuronal migration defects (e.g., lissencephaly), to mild forms of X-linked mental retardation without apparent brain abnormalities. The ARX-related disorders are reviewed focusing on their clinical features and on the role of…
The ASY-EOS experiment at GSI: Investigating the symmetry energy at supra-saturation densities
The elliptic-flow ratio of neutrons with respect to protons in reactions of neutron rich heavy-ions systems at intermediate energies has been proposed as an observable sensitive to the strength of the symmetry term in the nuclear Equation Of State (EOS) at supra-saturation densities. The recent results obtained from the existing FOPI/LAND data for $^{197}$Au+$^{197}$Au collisions at 400 MeV/nucleon in comparison with the UrQMD model allowed a first estimate of the symmetry term of the EOS but suffer from a considerable statistical uncertainty. In order to obtain an improved data set for Au+Au collisions and to extend the study to other systems, a new experiment was carried out at the GSI la…
Correlations between isospin dynamics and Intermediate Mass Fragments emission time scales: a probe for the symmetry energy in asymmetric nuclear matter
We show new data from the $^{64}$Ni+$^{124}$Sn and $^{58}$Ni+$^{112}$Sn reactions studied in direct kinematics with the CHIMERA detector at INFN-LNS and compared with the reverse kinematics reactions at the same incident beam energy (35 A MeV). Analyzing the data with the method of relative velocity correlations, fragments coming from statistical decay of an excited projectile-like (PLF) or target-like (TLF) fragments are discriminated from the ones coming from dynamical emission in the early stages of the reaction. By comparing data of the reverse kinematics experiment with a stochastic mean field (SMF) + GEMINI calculations our results show that observables from neck fragmentation mechani…
Probing the Merits of Different Event Parameters for the Identification of Light Charged Particles in CHIMERA CsI(Tl Detectors With Digital Pulse Shape Analysis
We investigated the merits of different event parameters in the identification of Light Charged Particles (LCPs) with CsI(Tl) scintillators read out by photodiodes at high incident energy (400 MeV/u). This investigation is made possible by digital signal processing the output signals. As in the conventional analogue case, the digitized signals allow the discrimination of light charged particles by computing the fast and slow components. In addition other identification parameters as the rise time of the output pulses of the CsI(Tl) come out nearly for free. Aim of this paper is the investigation of novel identification plots and the probe of their merits, in particular at relativistic energ…
Il progetto FARCOS/EXOCHIM
Elastic scattering studies of 16C at 50 MeV/A on proton and deuteron targets with the CHIMERA multidetector at INFN-LNS
At the Laboratori Nazionali del Sud (LNS) in Catania (Italy), light radioactive ion beams have been produced through the In Flight Fragmentation method, using 18O and 13C at 55 MeV/A as primary beams impinging on a 9Be production target. Elastic scattering angular distributions of 16C+p and 16C+d at 50 MeV/A, 10Be+p at 56 MeV/A and 13B+d at 52 MeV/A systems were measured by using the CHIMERA (Charge Heavy Ion Mass and Energy Resolving Array) multidetector and kinematical coincidence technique. The experimental data are fitted by using the optical model. © Published under licence by IOP Publishing Ltd.
Mapping the detector response of the FARCOS Double – Sided Silicon Strip Detectors with monochromatic single protons
N/Z effects on evaporation residue emission near fragmentation threshold
We will discuss results concerning the fate of hot nuclear systems populated in 40,48 Ca+ 40,48 Ca reactions at 25 MeV/nucleon. Due to the complexity of events, we used the Chimera 4π device as detection system. By selecting central events of reaction, we found that the interplay between binary-like and evaporation residue emissions is strongly sensitive on the N/Z of the entrance channels. In particular, evaporation residue emission increases at increasing the neutron content of colliding system. By comparing or data with CoMD-II model calculations, we can extract information about the density depend part of Symmetry Potential in the Nuclear Equation of State at near-saturation densities.