Choosing Optimal Seed Nodes in Competitive Contagion.
International audience; In recent years there has been a growing interest in simulating competitive markets to find out the efficient ways to advertise a product or spread an ideology. Along this line, we consider a binary competitive contagion process where two infections, A and B, interact with each other and diffuse simultaneously in a network. We investigate which is the best centrality measure to find out the seed nodes a company should adopt in the presence of rivals so that it can maximize its influence. These nodes can be used as the initial spreaders or advertisers by firms when two firms compete with each other. Each node is assigned a price tag to become an initial advertiser whi…
Integrating Environmental Temperature Conditions into the SIR Model for Vector-Borne Diseases
International audience; Nowadays, Complex networks are used to model and analyze various problems of real-life e.g. information diffusion in social networks, epidemic spreading in human population etc. Various epidemic spreading models are proposed for analyzing and understanding the spreading of infectious diseases in human contact networks. In classical epidemiological models, a susceptible person becomes infected after getting in contact with an infected person among the human population only. However, in vector-borne diseases, a human can be infected also by a living organism called a vector. The vector population that also help in spreading diseases is very sensitive to environmental f…
Centrality measures for networks with community structure
Understanding the network structure, and finding out the influential nodes is a challenging issue in the large networks. Identifying the most influential nodes in the network can be useful in many applications like immunization of nodes in case of epidemic spreading, during intentional attacks on complex networks. A lot of research is done to devise centrality measures which could efficiently identify the most influential nodes in the network. There are two major approaches to the problem: On one hand, deterministic strategies that exploit knowledge about the overall network topology in order to find the influential nodes, while on the other end, random strategies are completely agnostic ab…
An Efficient Immunization Strategy Using Overlapping Nodes and Its Neighborhoods
International audience; When an epidemic occurs, it is often impossible to vaccinate the entire population due to limited amount of resources. Therefore, it is of prime interest to identify the set of influential spreaders to immunize, in order to minimize both the cost of vaccine resource and the disease spreading. While various strategies based on the network topology have been introduced, few works consider the influence of the community structure in the epidemic spreading process. Nowadays, it is clear that many real-world networks exhibit an overlapping community structure, in which nodes are allowed to belong to more than one community. Previous work shows that the numbers of communit…
Effect of Topological Structure and Coupling Strength in Weighted Multiplex Networks
Algebraic connectivity (second smallest eigenvalue of the supra-Laplacian matrix of the underlying multilayer network) and inter-layer coupling strength play an important role in the diffusion processes on the multiplex networks. In this work, we study the effect of inter-layer coupling strength, topological structure on algebraic connectivity in weighted multiplex networks. The results show a remarkable transition in the value of algebraic connectivity from classical cases where the inter-layer coupling strength is homogeneous. We investigate various topological structures in multiplex networks using configuration model, the Barabasi-Albert model (BA) and empirical data-set of multiplex ne…
Community-based Immunization Strategies for Epidemic Control
Understanding the epidemic dynamics, and finding out efficient techniques to control it, is a challenging issue. A lot of research has been done on targeted immunization strategies, exploiting various global network topological properties. However, in practice, information about the global structure of the contact network may not be available. Therefore, immunization strategies that can deal with a limited knowledge of the network structure are required. In this paper, we propose targeted immunization strategies that require information only at the community level. Results of our investigations on the SIR epidemiological model, using a realistic synthetic benchmark with controlled community…
Immunization Strategies Based on the Overlapping Nodes in Networks with Community Structure
International audience; Understanding how the network topology affects the spread of an epidemic is a main concern in order to develop efficient immunization strategies. While there is a great deal of work dealing with the macroscopic topological properties of the networks, few studies have been devoted to the influence of the community structure. Furthermore, while in many real-world networks communities may overlap, in these studies non-overlapping community structures are considered. In order to gain insight about the influence of the overlapping nodes in the epidemic process we conduct an empirical evaluation of basic deterministic immunization strategies based on the overlapping nodes.…
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Contains fulltext : 232759.pdf (Publisher’s version ) (Closed access) In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to…
Autophagy
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide…
Optimal Local Routing Strategies for Community Structured Time Varying Communication Networks
International audience; In time varying data communication networks (TVCN), traffic congestion, system utility maximization and network performance enhancement are the prominent issues. All these issues can be resolved either by optimizing the network structure or by selecting efficient routing approaches. In this paper, we focus on the design of a time varying network model and propose an algorithm to find efficient user route in this network. Centrality plays a very important role in finding congestion free routes. Indeed, the more a node is central, the more it can be congested by the flow coming from or going to its neighborhood. For that reason, classically, routes are chosen such that…