0000000000061188

AUTHOR

Piergiorgio Calò

showing 7 related works from this author

Neomyogenesis in 3D Dynamic Responsive Prosthesis for Inguinal Hernia Repair

2018

Despite undisputed improvements, prosthetics hernia repair continues to be affected by unacceptable rates of complications. Postoperative adverse events such as discomfort and chronic pain represent a subject of increasing concern among the surgical community. Poor quality biologic response, stiff scar plates, and mesh shrinkage, a typical effect of conventional static meshes and plugs, are all indicated as the main reasons for many of the complications related to inguinal hernia repair. Even the conventional concept of treatment based upon a supposed reinforcement of the groin consequent to the fibrotic incorporation of meshes, would appear to be inadequate in the light of the latest scien…

medicine.medical_specialtyGroinbusiness.industryRegeneration (biology)medicine.medical_treatmentBiomedical EngineeringMedicine (miscellaneous)Connective tissueBioengineeringGeneral Medicine030230 surgerymedicine.diseaseHernia repairSurgeryBiomaterials03 medical and health sciencesInguinal hernia0302 clinical medicinemedicine.anatomical_structure030220 oncology & carcinogenesisMedicineMyocyteHerniaImplantbusinessArtificial Organs
researchProduct

Fixation free inguinal hernia repair with the 3D dynamic responsive prosthesis ProFlor: Features, procedural steps and long-term results

2019

Abstract Background Static and fixated meshes to repair mobile structures like the groin may seem a procedural incongruence. Inguinal hernia is described as a degenerative disease. Therefore, the objective of disease treatment should be the regeneration of wasted tissue. The fibrotic scar plate, a typical biologic response of conventional static meshes, does not represent tissue regeneration but rather a foreign body reaction. These contrasting aspects seem to be related to high complication rates of inguinal herniorrhaphy. Recent studies concerning the pathophysiology of the groin have led to the development of new concepts for repairing inguinal protrusions. A proprietary designed 3D dyna…

medicine.medical_specialtymedicine.medical_treatmentBiologic responseProsthesis03 medical and health sciences0302 clinical medicineDegenerative diseasemedicineTissue scaffoldsFixation (histology)Groinbusiness.industryDynamic responsive prosthesiInguinal herniaChronic painmedicine.diseaseSurgeryInguinal herniaSettore MED/18 - Chirurgia Generalemedicine.anatomical_structure030220 oncology & carcinogenesisTissue regeneration030211 gastroenterology & hepatologySurgeryImplantForeign bodybusiness
researchProduct

Lipoma of the fossa femoralis mimicking a femoral hernia. Report of 2 cases

2018

Highlights • Femoral lipoma can be mistaken with femoral hernia. • Differential diagnosis between femoral lipoma and femoral hernia can result challenging. • The occurrence of femoral pain can lead to misinterpretation of the symptoms.

medicine.medical_specialtyChronic compressive damagesFossaDifferential diagnosiPhysical examinationAsymptomaticArticleChronic compressive damage03 medical and health sciences0302 clinical medicineFemoral maUltrasoundotorhinolaryngologic diseasesmedicinebiologymedicine.diagnostic_testbusiness.industryFemoral herniafungiUltrasoundfood and beveragesLipomabiology.organism_classificationmedicine.diseaseFemoral ringFemoral herniaSurgerybody regionsstomatognathic diseasesmedicine.anatomical_structureFemoral mass030220 oncology & carcinogenesisDifferential diagnosis030211 gastroenterology & hepatologySurgeryLipomaDifferential diagnosismedicine.symptombusinessInternational Journal of Surgery Case Reports
researchProduct

The Septum Inguinalis: A Clue to Hernia Genesis?

2018

Purpose: Double ipsilateral inguinal ("pantaloon") hernias and also the more advanced "combined" inguinal hernia involve disruption of the inguinal floor. In the case of pantaloon hernias, the medial boundary of the internal ring remains intact but in combined hernias this is fully disrupted, producing a single hernial protrusion. Deepening the pathophysiology of these hernias may be helpful in addressing hernia genesis, thus improving strategies for the treatment of this disease. Materials and Methods: A cohort of 22 patients who underwent inguinal hernia repair showed double ipsilateral (pantaloon) hernia, comprising distinct direct and indirect protrusions separated by a tissue septum. I…

Malearterial obstructionetiologynerve degenerationInguinal CanalHernia Inguinalhernia03 medical and health sciences0302 clinical medicineTissue markersmedicineHumansHerniaHerniorrhaphyAgedAged 80 and overNerve degenerationbusiness.industryAbdominal WallInguinal herniamuscle degenerationMuscle degenerationAnatomyArterial obstructionMiddle Agedmedicine.diseasedigestive system diseasesseptum inguinalisstomatognathic diseasesInguinal herniasurgical procedures operativemedicine.anatomical_structure030220 oncology & carcinogenesisFemale030211 gastroenterology & hepatologySurgerybusinessInferior epigastric vessels
researchProduct

External hernia of the supravesical fossa: Rare or simply misidentified?

2017

Abstract Background External hernias of the supravesical fossa are considered rare, perhaps wrongly. Highlighting clinical and anatomical features could be useful for correct, preoperative diagnosis, thus avoiding the risk of complications such as incarceration. The study aims to demonstrate that the incidence of external protrusions of the supravesical fossa is higher that supposed. Probably, being mistaken for direct hernias, these hernia types are misidentified and not included in current classifications. This issue deserves attention due to the elevated risk of incarceration related to its distinctive structure. Material and methods 249 consecutive open anterior inguinal hernia procedur…

Malemedicine.medical_specialtyIndirect herniaIncarcerationHernia Inguinal030230 surgery03 medical and health sciencesSupravesical fossa0302 clinical medicinePathognomonicmedicineHumansHerniaSurgical treatmentHerniorrhaphyMedial umbilical foldRetrospective Studiesbusiness.industryCombined herniaInguinal herniaGeneral MedicineMiddle Agedmedicine.diseasedigestive system diseasesSurgerystomatognathic diseasesInguinal herniasurgical procedures operative030220 oncology & carcinogenesisHernia classificationSurgerySupravesical fossa herniaFemalebusinessKeywords: herniaHernia UmbilicalHumanInternational journal of surgery (London, England)
researchProduct

Neo-nervegenesis in 3D dynamic responsive implant for inguinal hernia repair. Qualitative study.

2020

Abstract Background Prosthetic repair of inguinal hernias is one of the most performed surgical procedures. Nevertheless, high rates of complications affect the surgical treatment. Implant fixation, poor-quality tissue ingrowth and mesh shrinkage seem to be involved in postoperative complications, discomfort and chronic pain following inguinal hernia repair. To address these issues a multilamellar shaped 3D dynamic responsive prosthesis has been developed. This new implant, positioned fixation-free to obliterate the hernia opening, thanks its inherent dynamic compliance during inguinal movements, has demonstrated to induce an enhanced biological response. The ingrowth of newly formed muscle…

medicine.medical_specialtyNeo-nervegenesimedicine.medical_treatmentConnective tissueArtificial LimbsHernia InguinalGroinProsthesisProsthesis Implantation03 medical and health sciences0302 clinical medicinePostoperative ComplicationsProstheseBiopsymedicineHumansHerniaTissue scaffoldsHerniorrhaphyQualitative ResearchGroinmedicine.diagnostic_testbusiness.industryInguinal herniaNerveGeneral MedicineSurgical Meshmedicine.diseaseHernia repairSurgerySettore MED/18 - Chirurgia GeneraleInguinal herniamedicine.anatomical_structure030220 oncology & carcinogenesisPrinting Three-DimensionalTissue regeneration030211 gastroenterology & hepatologySurgeryImplantbusinessInternational journal of surgery (London, England)
researchProduct

First-in-man permanent laparoscopic fixation free obliteration of inguinal hernia defect with the 3D dynamic responsive implant ProFlor-E®. Case repo…

2020

Abstract Introduction In the case of inguinal hernia recurrence after primary anterior repair, international guidelines strongly suggest a posterior laparoscopic approach. The 3D dynamic-responsive prosthesis for inguinal hernia repair ProFlor-E® has recently been introduced to the market. The present report describes the results of the first-in-man laparoscopic inguinal hernia repair carried out with ProFlor-E®. Presentation of case A 71-year-old male Caucasian presented with recurrent inguinal hernia after primary anterior repair. A fixation free TAPP procedure with ProFlor-E® was planned. Implant delivery and placement to obliterate the defect was quick and safe. Postoperatively, startin…

medicine.medical_specialtyRegenerative scaffoldmedicine.medical_treatmentCase ReportProFlor prosthesisProsthesisMesh fixation03 medical and health sciencesFixation (surgical)0302 clinical medicineLaparoscopicInguinal hernia repairMedicineHerniaDynamic responsivitybusiness.industryChronic painInvaginationmedicine.diseaseSurgeryInguinal herniaFixation free hernia repair030220 oncology & carcinogenesis030211 gastroenterology & hepatologySurgeryImplantbusinessInternational Journal of Surgery Case Reports
researchProduct