0000000000064299
AUTHOR
Salvatore Magazù
IRIDE: Interdisciplinary research infrastructure based on dual electron linacs and lasers
This paper describes the scientific aims and potentials as well as the preliminary technical design of RUDE, an innovative tool for multi-disciplinary investigations in a wide field of scientific, technological and industrial applications. IRIDE will be a high intensity "particles factory", based on a combination of high duty cycle radio-frequency superconducting electron linacs and of high energy lasers. Conceived to provide unique research possibilities for particle physics, for condensed matter physics, chemistry and material science, for structural biology and industrial applications, IRIDE will open completely new research possibilities and advance our knowledge in many branches of sci…
Thermostabilization of BSA in TMAO Water Mixtures by Infrared Spectroscopy
Background:Trimethylamine-N-Oxide (TMAO) is a small organic molecule derived from the metabolism of L-carnitine and choline after ingestion of animal food. TMAO has many functions such as electron acceptor, an osmolyte, stabilizer of macromolecules folding. It seems that TMAO plays an important role in nature but, in humans, it is a remnant of the evolution of the osmolyte system.Objective:The present paper is addressed on the study of thermal stability of hydrated Bovine Serum Albumins (BSA) in the presence of water and TMAO water solution by means of InfraRed spectroscopy. In particular, this work has investigated the protein amide I spectral regions, which is sensitive to protein seconda…
Effects of isotopic substitution on the conformational properties of polymeric aqueous solutions
Abstract This work deals with a side-by-side comparison between the PEO conformational properties in H 2 O and D 2 O. The gyration radius, evaluated by SANS, the hydrodynamic radius, evaluated by PCS, and the Raman D-LAM band analysis furnish valuable information on the structural arrangement of the molecules. The findings clearly show different behavioural properties of the polymer in H 2 O and D 2 O.
Indoor Fast Neutron Generator for Biophysical and Electronic Applications
This study focuses the attention on an indoor fast neutron generator for biophysical and electronic applications. More specifically, the findings obtained by several simulations with the MCNP Monte Carlo code, necessary for the realization of a shield for indoor measurements, are presented. Furthermore, an evaluation of the neutron spectrum modification caused by the shielding is reported. Fast neutron generators are a valid and interesting available source of neutrons, increasingly employed in a wide range of research fields, such as science and engineering. The employed portable pulsed neutron source is a MP320 Thermo Scientific neutron generator, able to generate 2.5 MeV neutrons with a …
QENS from polymer aggregates in supercritical CO2
Abstract We report QENS measurements from PS-b-PFOA aggregates in supercritical CO2. Line shapes are dominated by localized diffusive modes and segmental dynamics of the anchored, finite-length PFOA chains. For Q⩽0.6 A−1, we obtain effective diffusion coefficients of ≅0.8 10−6 cm2/s. At higher Q, a single component is not sufficient as shown by excess intensity on the flanks. For Q⩾1.5 A−1, the wings reflect contributions due to a distribution of faster, more localized chain modes.
Thermal restraint of a bacterial exopolysaccharide of shallow vent origin
This is the post-print version of the following article: "Thermal restraint of a bacterial exopolysaccharide of shallow vent origin", which has been published in final form at https://www.sciencedirect.com/science/article/pii/S0141813018308250?via%3Dihub; International audience; To dynamically characterize the thermal properties of the fructose-rich exopolysaccharide (EPS1-T14), produced by themarine thermophilic Bacillus licheniformis T14, the Attenuated Total Reflectance Fourier Transform Infra-Redspectroscopy was coupled to variable temperature ranging from ambient to 80 °C.The spectra were analyzed by the following innovative mathematical tools: i) non-ideal spectral deviation, ii) OHst…
QENS from polymeric micelles in supercritical CO[sub 2]
We report QENS measurements from PS-b-PFOA aggregates in supercritical CO2. These consist of dense cores of CO2-insoluble polystyrene surrounded by a ‘corona’ of PFOA surfactant molecules whose CO2-philic groups interface with supercritical CO2. Lineshapes are dominated by localized diffusive modes and segmental dynamics of the anchored, finite-length PFOA chains. For Q∼0.6 A−1, we obtain effective diffusion coefficients of ≈0.8×10−6 cm2/sec. At higher Q, a single component is not sufficient as shown by excess intensity on the flanks. For Q>1.5 A−1, the wings reflect contributions due to a distribution of faster, more localized chain modes.
Structural investigation of the confinement of finite amounts of trehalose in water-containing sodium bis(2-ethylhexyl)sulfosuccinate reversed micelles
The structural effect of trehalose confined in water-containing sodium bis(2-ethylhexyl)sulfosuccinate (AOT) reversed micelles at water to AOT molar ratio W = 5 and 10 as a function of the trehalose to AOT molar ratio T (0 < T < 0.1) has been investigated by small-angle neutron scattering (SANS). SANS data analysis is consistent with the hypothesis that trehalose is encapsulated within the quite spherical hydrophilic micellar cores of water-containing reversed micelles, causing an increase of the aggregate size and a decrease of the polydispersion. Moreover, SANS results suggest that the trehalose confinement in water-containing reversed micelles involves marked changes on the molecular pac…