0000000000065353

AUTHOR

Omid Nikoubashman

showing 10 related works from this author

Necessary Catheter Diameters for Mechanical Thrombectomy with ADAPT

2017

BACKGROUND AND PURPOSE: Large-bore catheters allow mechanical thrombectomy in ischemic stroke by engaging and retrieving clots without additional devices (direct aspiration first-pass technique [ADAPT]). The purpose of this study was to establish a model for minimal catheter diameters needed for ADAPT. MATERIALS AND METHODS: We established a theoretic model for the calculation of minimal catheter diameters needed for ADAPT. We then verified its validity in 28 ADAPT maneuvers in a porcine in vivo model. To account for different mechanical thrombectomy techniques, we factored in ADAPT with/without a hypothetic 0.021-inch microcatheter or 0.014-inch microwire inside the lumen of the aspiration…

CathetersMechanical ThrombolysisSwine030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinemedicine.arterymedicineInner diameterAnimalsRadiology Nuclear Medicine and imagingAspiration catheterInterventionalbusiness.industryPredictive valueMechanical thrombectomyStrokeCatheterTreatment OutcomeMiddle cerebral arteryNeurology (clinical)Internal carotid arterybusinessTheoretic model030217 neurology & neurosurgeryBiomedical engineering
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Optimizing endovascular stroke treatment: removing the microcatheter before clot retrieval with stent-retrievers increases aspiration flow

2016

BackgroundFlow control during endovascular stroke treatment with stent-retrievers is crucial for successful revascularization. The standard technique recommended by stent-retriever manufacturers implies obstruction of the respective access catheter by the microcatheter, through which the stent-retriever is delivered. This, in turn, results in reduced aspiration during thrombectomy. In order to maximize aspiration, we fully retract the microcatheter out of the access catheter before thrombectomy—an approach we term the ‘bare wire thrombectomy’ (BWT) technique. We verified the improved throughput with systematic in vitro studies and assessed the clinical effectiveness and safety of this metho…

AdultMalemedicine.medical_specialtyCathetersAdolescentmedicine.medical_treatmentRevascularizationBalloon030218 nuclear medicine & medical imagingYoung Adult03 medical and health sciences0302 clinical medicinemedicineHumansProspective StudiesChildStrokeAgedRetrospective StudiesThrombectomyStent retrieverAged 80 and overbusiness.industryEndovascular ProceduresStentGeneral MedicineMiddle Agedmedicine.diseaseStandard techniqueSurgeryStrokeStroke treatmentCatheterTreatment OutcomeFemaleStentsSurgeryNeurology (clinical)Radiologybusiness030217 neurology & neurosurgeryJournal of NeuroInterventional Surgery
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Endovascular stentectomy using the snare over stent-retriever (SOS) technique: An experimental feasibility study

2017

PLoS one 12(5), e0178197 (2017). doi:10.1371/journal.pone.0178197

GlycerolSwinePhysiologylcsh:Medicine030218 nuclear medicine & medical imaging0302 clinical medicinePig ModelsBlood FlowMedicine and Health SciencesMedicinelcsh:ScienceData flow modelClinical scenarioMammalsMultidisciplinaryExperimental DesignEndovascular ProceduresVasospasmAnimal ModelsProsthesis FailureBody FluidsPhysical sciencesChemistryBloodExperimental Organism SystemsResearch DesignVertebratesFemaleStentsRadiologyAnatomyResearch ArticleBiotechnologymedicine.medical_specialtyCathetersSurgical and Invasive Medical ProceduresMonomers (Chemistry)Research and Analysis Methods03 medical and health sciencesAnimal modelText miningIn vivoBlood vessel prosthesisAnimalsHumansPolymer chemistryStent retrieverbusiness.industrylcsh:ROrganismsBiology and Life Sciencesmedicine.diseaseBlood Vessel ProsthesisDisease Models AnimalStent ImplantationAmniotesFeasibility StudiesMedical Devices and Equipmentlcsh:Qbusiness030217 neurology & neurosurgeryPLOS ONE
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Under Pressure: Comparison of Aspiration Techniques for Endovascular Mechanical Thrombectomy.

2018

BACKGROUND AND PURPOSE: Blood flow should be interrupted during mechanical thrombectomy to prevent embolization of clot fragments. The purpose of our study was to provide a handy overview of the most common aspiration devices and to quantify their flow characteristics. MATERIALS AND METHODS: We assessed volumetric flow rates generated by a 60-mL VacLok vacuum pressure syringe, a Pump MAX aspiration pump, and a Dominant Flex suction pump connected to the following: 1) an 8F long sheath, 2) an 8F balloon-guide catheter, 3) an ACE 64 distal aspiration catheter, and 4) an AXS Catalyst 6 Distal Access Catheter. We used a water/glycerol solution, which was kept at a constant temperature of 20°C (…

Cathetersmedicine.medical_treatmentVacuum pressureSuctionBalloonModels Biological030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinemedicineHumansRadiology Nuclear Medicine and imagingEmbolizationSyringeThrombectomyAspiration catheterInterventionalbusiness.industrySyringesEndovascular ProceduresBlood flowMechanical thrombectomyCatheterNeurology (clinical)business030217 neurology & neurosurgeryBiomedical engineeringAJNR. American journal of neuroradiology
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Platelet function testing in pigs using the Multiplate® Analyzer.

2019

PLOS ONE 14(8), e0222010 (2019). doi:10.1371/journal.pone.0222010

Platelet AggregationSwinePhysiology030204 cardiovascular system & hematologyPlatelet inhibitionPharmacologyAntiplatelet Therapy0302 clinical medicineOral administrationAnimal CellsPig ModelsMedicine and Health SciencesMedicinePlateletOral AdministrationRoutes of AdministrationMammalsMultidisciplinaryPharmaceuticsQREukaryotaHematologyAnimal ModelsClopidogrelBody FluidsBloodExperimental Organism SystemsVertebratesMedicineAnatomyCellular Typesmedicine.drugResearch ArticleBlood PlateletsPlateletsPlatelet Function TestsScience610Research and Analysis Methods03 medical and health sciencesAnimal modelDrug TherapyAnimalsddc:610Platelet activationBlood CoagulationApplication methodsPharmacologyBlood CellsAspirinbusiness.industryOrganismsBiology and Life Sciences030208 emergency & critical care medicineCell BiologyPlatelet ActivationReference valuesAmniotesPurinergic P2Y Receptor AntagonistsAnimal StudiesbusinessPlatelet Aggregation InhibitorsPloS one
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Implant-specific follow-up imaging of treated intracranial aneurysms: TOF-MRA vs. metal artifact reduced intravenous flat panel computed tomography a…

2017

Aim To compare the diagnostic quality of time-of-flight magnetic resonance angiography (TOF-MRA) and metal-artefact-reduction (MAR) flat-panel-detector computed tomography angiography (FPCTA) and to determine the imaging technique best suited for evaluation endovascular and surgically treated aneurysms. Methods The image quality of TOF-MRA and MAR-FPCTA of 44 intracranial implants (coiling: n= 20; clipping: n= 15; coiling + stenting: n= 9) in a patient cohort of 25 was evaluated by two independent readers. Images obtained using MAR-FPCTA (20 second scan time, 496 projections, intravenous contrast medium administration; Artis Zee, Siemens Healthcare, Forchheim) were compared with TOF-MRA-ima…

medicine.medical_specialtyWilcoxon signed-rank testImage qualityComputed Tomography Angiographymedicine.medical_treatmentContrast MediaMagnetic resonance angiography030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineAneurysmMcNemar's testmedicineImage Processing Computer-AssistedHumansRadiology Nuclear Medicine and imagingcardiovascular diseasesComputed tomography angiographyRetrospective Studiesmedicine.diagnostic_testbusiness.industryIntracranial AneurysmGeneral MedicineClipping (medicine)Prostheses and Implantsmedicine.diseaseImage EnhancementSurgical InstrumentsCerebral AngiographyMetalscardiovascular systemStentsImplantRadiologybusinessArtifacts030217 neurology & neurosurgeryMagnetic Resonance AngiographyFollow-Up StudiesClinical radiology
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Long Term Outcome after Application of the Angio-Seal Vascular Closure Device in Minipigs

2016

PLoS one 11(9), e0163878 (2016). doi:10.1371/journal.pone.0163878

SwineAnticoagulant Therapylcsh:MedicineFemoral artery030204 cardiovascular system & hematologyPathology and Laboratory Medicine030218 nuclear medicine & medical imagingWhite Blood Cells0302 clinical medicinePig ModelsAnimal CellsMedicine and Health SciencesVascular closure deviceLymphocyteslcsh:ScienceComputed tomography angiographyMammalsStenosisMultidisciplinarymedicine.diagnostic_testPharmaceuticsAgricultureArteriesAnimal ModelsClopidogrelCardiovascular Therapymedicine.anatomical_structureVertebratesAnatomyCellular TypesArterymedicine.drugResearch Articlemedicine.medical_specialtyLivestockImmune CellsAnimal TypesImmunologyLumen (anatomy)Research and Analysis Methods03 medical and health sciencesSigns and SymptomsModel OrganismsDrug TherapyDiagnostic Medicinemedicine.arterymedicineAnimalsDomestic AnimalsBlood Cellsbusiness.industrylcsh:ROrganismsBiology and Life SciencesCell BiologyFemoral ArteriesInternal elastic laminamedicine.diseaseSurgeryStenosisAmniotesCardiovascular AnatomyBlood Vesselslcsh:QbusinessZoologyPLoS ONE
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Minimally Invasive Monitoring of Chronic Central Venous Catheter Patency in Mice Using Digital Subtraction Angiography (DSA)

2015

PLoS ONE 10(6), e0130661 (2015). doi:10.1371/journal.pone.0130661

MaleCatheterization Central Venousmedicine.medical_specialtymedicine.medical_treatmentlcsh:MedicineContrast MediaMiceJugular veinOcclusionmedicineAnimalsCentral Venous Catheterslcsh:ScienceSalineMultidisciplinarymedicine.diagnostic_testbusiness.industrylcsh:RAngiography Digital SubtractionDigital subtraction angiographyBlood flowMice Inbred C57BLCatheterAngiographylcsh:QRadiologybusinessCentral venous catheterResearch Article
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Imaging of Ventriculoperitoneal Shunt Complications: Comparison of Whole Body Low-Dose Computed Tomography and Radiographic Shunt Series.

2016

OBJECTIVE To determine diagnostic value and radiation exposure of low-dose computed tomography (LD-CT) compared to radiographic shunt series (SS) for the detection of ventriculoperitoneal (VP) shunt complications. METHODS Fourteen VP shunts were implanted in 7 swine cadavers. Mechanical complications were induced in 50% of VP shunts. Low-dose CT (80 kVp, 10 mAs, Pitch = 1.5) and SS were acquired. Dose area product (DAP) and effective doses for SS and LD-CT were collected. Scoring of diagnostic confidence and blinded readings of SS and CT data were performed. RESULTS The sensitivity of LD-CT was high (0.97; 95% confidence interval, 0.91-1.00) with excellent interobserver agreement (κ = 0.88)…

medicine.medical_specialtySwineRadiographyComputed tomographyRadiation DosageEffective dose (radiation)Sensitivity and SpecificityVentriculoperitoneal Shunt030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinePostoperative ComplicationsRadiation ProtectionmedicineAnimalsRadiology Nuclear Medicine and imagingMedical physicsSingle-Blind MethodWhole Body Imagingmedicine.diagnostic_testbusiness.industryLow doseReproducibility of ResultsRadiation ExposureConfidence intervalRadiographic Image EnhancementDose area productRadiographic Image Interpretation Computer-AssistedTomographybusinessNuclear medicineTomography X-Ray Computed030217 neurology & neurosurgeryShunt (electrical)Journal of computer assisted tomography
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Influence of carotid tortuosity on internal carotid artery access time in the treatment of acute ischemic stroke

2017

Purpose Carotid artery anatomy is thought to influence internal carotid artery access time (ICA-AT) in patients requiring mechanical thrombectomy for acute ischemic stroke. This study investigates the association between ICA-AT and carotid anatomy. Material and methods Computed tomography angiography (CTA) data of 76 consecutive patients presenting with acute ischemic stroke requiring mechanical thrombectomy for middle cerebral artery or carotid T occlusion were evaluated. The supraaortic extracranial vasculature was analyzed regarding take-off angles and curvature of the affected side. Digital subtraction angiography data were primarily analyzed regarding ICA-AT and secondarily regarding r…

Malemedicine.medical_specialtyComputed Tomography AngiographyMechanical ThrombolysisTortuosityBrain Ischemia030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinemedicine.arteryInternal medicineHumansMedicineCarotid StenosisIn patientAcute ischemic strokeAgedbusiness.industryAngiography Digital SubtractionCerebral AngiographyStrokeMechanical thrombectomyTreatment Outcomemedicine.anatomical_structurecardiovascular systemCardiologyFemaleInternal carotid arterybusinessCarotid Artery Internal030217 neurology & neurosurgeryArteryInterventional Neuroradiology
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