0000000000067946

AUTHOR

Tanea T. Reed

0000-0003-2642-3100

showing 2 related works from this author

Harmful and Beneficial Role of ROS 2017.

2018

0301 basic medicineAgingArticle SubjectReactive oxygen species metabolismFree Radicalslcsh:CytologyMEDLINECell BiologyGeneral MedicineBiologyBioinformaticsBiochemistryAntioxidants03 medical and health sciencesOxidative Stress030104 developmental biologyEditorialAnimalslcsh:QH573-671Reactive Oxygen SpeciesIntroductory Journal ArticleSignal TransductionOxidative medicine and cellular longevity
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Insulin resistance and diabetes in hyperthyroidism: a possible role for oxygen and nitrogen reactive species.

2019

In addition to insulin, glycemic control involves thyroid hormones. However, an excess of thyroid hormone can disturb the blood glucose equilibrium, leading to alterations of carbohydrate metabolism and, eventually, diabetes. Indeed, experimental and clinical hyperthyroidism is often accompanied by abnormal glucose tolerance. A common characteristic of hyperthyroidism and type 2 diabetes is the altered mitochondrial efficiency caused by the enhanced production of reactive oxygen and nitrogen species. It is known that an excess of thyroid hormone leads to increased oxidant production and mitochondrial oxidative damage. It can be hypothesised that these species represent the link between hype…

0301 basic medicinemedicine.medical_specialtyendocrine systemendocrine system diseasesmedicine.medical_treatmentDiabetes hyperthyroidism insulin resistance insulin secretion reactive nitrogen species (RNS) reactive oxygen species (ROS)Type 2 diabetesCarbohydrate metabolismBiochemistryHyperthyroidism03 medical and health sciencesInsulin resistanceDiabetes mellitusInternal medicinemedicineHumansGlycemic030102 biochemistry & molecular biologyChemistryInsulinThyroidGeneral Medicinemedicine.diseaseReactive Nitrogen SpeciesOxygen030104 developmental biologymedicine.anatomical_structureEndocrinologyDiabetes Mellitus Type 2Insulin ResistanceReactive Oxygen SpeciesHormoneFree radical research
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