0000000000068839

AUTHOR

Stefano Salvadori

0000-0002-1266-3931

showing 3 related works from this author

Objective assessment of blinking and facial expressions in Parkinson’s disease using a vertical electro-oculogram and facial surface electromyography

2019

Objective: Hypomimia is a common and early symptom of Parkinson's disease (PD), which reduces the ability of PD patients to manifest emotions. Currently, it is visually evaluated by the neurologist during neurological examinations for PD diagnosis, as described in task 3.2 of the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS). Since such an evaluation is semi-quantitative and affected by inter-variability, this paper aims to measure the physiological parameters related to eye blink and facial expressions extracted from a vertical electro-oculogram (VEOG) and facial surface electromyography (fsEMG) to differentiate PD patients from healthy control subjects (…

Malemedicine.medical_specialtyvertical electro-oculogramParkinson's diseasegenetic structuresPhysiologyParkinson's disease0206 medical engineeringElectro oculogramBiomedical EngineeringBiophysicsHypomimia02 engineering and technologyElectromyographyAudiologyObjective assessment03 medical and health sciences0302 clinical medicineRating scalePhysiology (medical)spontaneous eye blink rateHumansMedicineElectrodesAgedFacial expressionBlinkingmedicine.diagnostic_testElectromyographybusiness.industryParkinson DiseaseSignal Processing Computer-AssistedElectrooculographymedicine.disease020601 biomedical engineeringfacial surface emgFacial ExpressionElectrooculographyROC CurveArea Under CurveCase-Control StudiesFemalemedicine.symptombusiness030217 neurology & neurosurgeryPhysiological Measurement
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Assessment of prevalence and load of torquetenovirus viraemia in a large cohort of healthy blood donors.

2020

OBJECTIVES: Torquetenovirus (TTV) is an emerging marker of functional immune competence with the potential to predict transplant-related adverse events. A large-scale epidemiological study was performed to understand how basal values vary in healthy individuals according to age and gender.; METHODS: We tested plasma from 1017 healthy blood donors aged 18-69years. The presence and load of TTV were determined by a real-time PCR assay. A sub-cohort of 384 donors was tested for anti-cytomegalovirus IgG antibodies, and 100 participants were also tested for TTV viraemia on a paired whole blood sample.; RESULTS: The overall prevalence of TTV was 65% (657/1017) with a mean (±SD) growth of 5±4% ever…

0301 basic medicineMicrobiology (medical)AdultMalemedicine.medical_specialtyAgingAdolescentprevalence030106 microbiologyPcr assayPhysiologyTTVViremiaBlood DonorsanelloviridaeReal-Time Polymerase Chain Reaction03 medical and health sciencesPlasmaYoung Adult0302 clinical medicineEpidemiologyMedicineHumansBlood Transfusion030212 general & internal medicineViremiaTTV; anelloviridae; blood donors; healthy controls; prevalence; torquetenovirus; viremiaAdverse effectWhole bloodAgedTorque teno virusbiologybusiness.industryGeneral MedicineMiddle AgedViral Loadmedicine.diseaseDNA Virus InfectionsHealthy VolunteersLarge cohorttorquetenovirusInfectious DiseasesHealthy individualsDNA Viralbiology.proteinhealthy controlsFemaleAntibodybusinessClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
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Hands-feet wireless devices: Test-retest reliability and discriminant validity of motor measures in Parkinson's disease telemonitoring

2022

Background Telemonitoring, a branch of telemedicine, involves the use of technological tools to remotely detect clinical data and evaluate patients. Telemonitoring of patients with Parkinson's disease (PD) should be performed using reliable and discriminant motor measures. Furthermore, the method of data collection and transmission, and the type of subjects suitable for telemonitoring must be well defined. Objective To analyze differences in patients with PD and healthy controls (HC) with the wearable inertial device SensHands-SensFeet (SH-SF), adopting a standardized acquisition mode, to verify if motor measures provided by SH-SF have a high discriminating capacity and high intraclass corr…

motor function assessmentFootParkinson's diseasesubclinical motor abnormalitieswearable sensorsReproducibility of ResultstelemonitoringParkinson DiseaseGeneral MedicineWearable Electronic DevicesNeurologyHumansbiomechanical parametersSettore MED/26 - NeurologiaNeurology (clinical)telemedicineGait
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