showing 5 related works from this author
GraftFast Surface Engineering to Improve MOF Nanoparticles Furtiveness
2018
International audience; Controlling the outer surface of nanometric metal–organic frameworks (nanoMOFs) and further understanding the in vivo effect of the coated material are crucial for the convenient biomedical applications of MOFs. However, in most studies, the surface modification protocol is often associated with significant toxicity and/or lack of selectivity. As an alternative, how the highly selective and general grafting GraftFast method leads, through a green and simple process, to the successful attachment of multifunctional biopolymers (polyethylene glycol (PEG) and hyaluronic acid) on the external surface of nanoMOFs is reported. In particular, effectively PEGylated iron trime…
Design of stable mixed-metal MIL-101(Cr/Fe) materials with enhanced catalytic activity for the Prins reaction
2020
[EN] This work highlights the benefit of designing mixed-metal (Cr/Fe) MOFs for enhanced chemical stability and catalytic activity. A robust and stable mixed-metal MIL-101(Cr/Fe) was prepared through a HF-free direct hydrothermal route with Fe(3+)content up to 21 wt%. The incorporation of Fe(3+)cations in the crystal structure was confirmed by(57)Fe Mossbauer spectrometry. The catalytic performance of the mixed metal MIL-101(Cr/Fe) was evaluated in the Prins reaction. MIL-101(Cr/Fe) exhibited a higher catalytic activity compared to MIL-101(Cr), improved chemical stability compared to MIL-101(Fe) and a higher catalytic activity for bulky substrates compared to MIL-100(Fe).In situinfra-red sp…
Exploring the catalytic performance of a series of bimetallic MIL-100(Fe, Ni) MOFs
2019
[EN] A series of mixed-metal Fe-III/Ni-II metal-organic frameworks (MOFs) of the MIL-100 type containing different metal ratios have been synthesized de novo, following an approach that requires tuning of the Fe-III/Ni-II reactivity. The resulting heterometallic MIL-100(Fe, Ni) materials maintain thermal, chemical and structural stability with respect to the parent MIL-100(Fe) MOF as can be deduced from various techniques. The nature and the oxidation state of the accessible metal cations have been evaluated by in situ infrared spectroscopy and extended X-ray absorption fine structure measurements. The obtained mixed-metal MOFs and the parent material have been evaluated as heterogeneous ca…
Chitosan-coated mesoporous MIL-100(Fe) nanoparticles as improved bio-compatible oral nanocarriers
2017
Nanometric biocompatible Metal-Organic Frameworks (nanoMOFs) are promising candidates for drug delivery. Up to now, most studies have targeted the intravenous route, related to pain and severe complications; whereas nanoMOFs for oral administration, a commonly used non-invasive and simpler route, remains however unexplored. We propose here the biofriendly preparation of a suitable oral nanocarrier based on the benchmarked biocompatible mesoporous iron(III) trimesate nanoparticles coated with the bioadhesive polysaccharide chitosan (CS). This method does not hamper the textural/structural properties and the sorption/release abilities of the nanoMOFs upon surface engineering. The interaction …
Metal-Organic Framework Surface Functionalization: GraftFast Surface Engineering to Improve MOF Nanoparticles Furtiveness (Small 40/2018)
2018
International audience