Author: Santiago Matías Ruatta

0000000000074334

AUTHOR

Santiago Matías Ruatta

showing 2 related works from this author

Regio-specific synthesis of new 1-(tert-butyl)-1H-pyrazolecarboxamide derivatives

2017

Regio-specific and non-regiospecific condensation reactions on 1,3-dicarbonyl compounds rendered 1,3,5-trisubstituted pyrazoles. Herein, the control of regio-specificity was a significant improvement in pyrazole research. A high yield acylation of poorly nucleophilic aryl amines, which resulted in mono- or diacylated products depending on the reaction conditions, is described. As a result, a library of potentially bioactive compounds was obtained. Fil: Ruatta Merke, Santiago Matías. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina Fil: Murguia, Marcelo Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Co…

Arylamine acylationRegio-specific condensationPyrazole010402 general chemistry01 natural sciencesBiochemistryAcylationchemistry.chemical_compoundNucleophileDrug DiscoveryOrganic chemistryTert butylReaction conditions010405 organic chemistryChemistryArylOtras Ciencias Químicastert-Butyl hydrazineOrganic ChemistryCiencias QuímicasPyrazole carboxamideCondensation reaction0104 chemical sciencesDiacylationYield (chemistry)CIENCIAS NATURALES Y EXACTAS

researchProduct

CCDC 1536511: Experimental Crystal Structure Determination

2017

Related Article: Santiago Matías Ruatta, Marcelo César Murguía, Carmen Ramírez de Arellano, Santos Fustero|2017|Tetrahedron Lett.|58|2441|doi:10.1016/j.tetlet.2017.05.029

Space GroupCrystallography1-t-butyl-5-(furan-2-yl)-N-(4-nitrophenyl)-1H-pyrazole-3-carboxamideCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates

researchProduct

PEPhysical Sciences and Engineering
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