0000000000074444

AUTHOR

Gianna Maria Nardi

showing 2 related works from this author

Clinical and Microbiologic Effects of Subgingival Controlled-Release Delivery of Chlorhexidine Chip in the Treatment of Periodontitis: A Multicenter …

2008

Background: The main therapeutic approach for periodontal diseases is mechanical treatment of root surfaces via scaling and root planing (SRP). Multicenter clinical trials have demonstrated that the adjunctive use of a chlorhexidine (CHX) chip is effective in improving clinical results compared to SRP alone. However, some recent studies failed to confirm these clinical results, and conflicting results were reported regarding the effects of the CHX chip on subgingival microflora. The aim of this study was to provide further data on the clinical and microbiologic effects of CHX chips when used as an adjunct to SRP. Methods: A total of 116 systemically healthy individuals with moderate to adva…

AdultDNA BacterialMalemedicine.drug_classBleeding on probingColony Count MicrobialDental PlaqueDentistryStatistics Nonparametriclaw.inventionBacteria AnaerobicScaling and root planingAntisepticRandomized controlled triallawChlorhexidine/therapeutic use controlled clinical trial drug delivery system periodontitis/therapymedicineHumansSingle-Blind MethodperiodontitisAgedPeriodontitischlorexidine; periodontitis; periodontitis/therapy; controlled clinical trial; drug delivery systems; chlorhexidine/therapeutic usebusiness.industryChlorhexidineChlorhexidinePeriodontologyMiddle Agedmedicine.diseaseClinical trialDelayed-Action PreparationsMultivariate AnalysisAnti-Infective Agents LocalDental ScalingPeriodonticsFemalePeriodontal Indexmedicine.symptombusinessmedicine.drugJournal of Periodontology
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Direct visualization of oral-cavity tissue fluorescence as novel aid for early oral cancer diagnosis and potentially malignant disorders monitoring.

2011

Direct visualization of the oral tissue autofluorescence has been recently reviewed in several studies as a possible adjunctive tool for early recognition and diagnosis of potentially malignant and malignant oral disorders. The aims of this study were to assess: a) the value of a simple handheld device for tissue auto-fluorescence visualization of potentially malignant oral lesions; and b) the sensitivity, specificity and diagnostic accuracy of tested device, using histological examination as the gold standard. 175 consecutive patients, with at least one clinical oral lesion, were enrolled in the study. Clinical conventional inspections were performed for each patient by two blind operator…

AdultMaleMild DysplasiaPathologymedicine.medical_specialtyEpithelial dysplasiaImmunologySettore MED/50 - Scienze Tecniche Mediche ApplicateautofluorescenceFluorescenceYoung Adultoral lichen planusPredictive Value of TestsOPMD fluorescenceSettore MED/28 - Malattie OdontostomatologicheBiopsyepithelial dysplasiamedicineHumansImmunology and AllergyEarly Detection of CancerAgedLeukoplakiaAged 80 and overPharmacologyMouthmedicine.diagnostic_testbusiness.industryDiagnosis OralMiddle Agedoral cancermedicine.diseaseautofluorescence; epithelial dysplasia; leukoplakia; oral cancer; oral lichen planus;stomatognathic diseasesDysplasialeukoplakiaFemaleMouth NeoplasmsHistopathologyOral lichen planusbusinessPrecancerous ConditionsOral medicine
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