0000000000075478
AUTHOR
G. Cilluffo
A survey around the Italian pediatric units on current clinical practice for Sleep Disordered Breathing (SDB)
Background During recent years, interest on Sleep Disordered Breathing (SDB) in pediatric age has increased, due to the impact on quality of life, psycho-physical attitude and other serious morbidities if undiagnosed and untreated. Methods Italian Pediatric Respiratory Diseases Society (SIMRI) SDB-Working Group carried out an exploratory survey in Italy, from January to December 2016, to assess the diagnostic and therapeutic pathways, perception and relevance of SDB in Italian Hospitals. Results A questionnaire was sent to 180 Pediatric Units (PUs) distributed throughout the Italy; 102 Pediatric Units (PUs; 56.6%) answered and among them 57% dealt with SDB, and 94% recognized SDB as a major…
Induced smoothing in LASSO regression
The thesis is being carried out with the National research Council at the Institute of Biomedicine and Molecular Immunology "Alberto Monroy" of Palermo, where I am a fellow, under the supervision of MD Stefania La Grutta. Our research unit is focused on clinical research in allergic respiratory problems in children. In particular, we are interested in to assess the determinants of impaired lung function in a sample of outpatient asthmatic children aged between 5 and 17 years enrolled from 2011 to 2017. Our dataset is composed by n = 529 children and several covariates regarding host and environmental factors. This thesis focuses on hypothesis testing in lasso regression, when one is interes…
Relationship between quality of life and behavioural disorders in children with persistent asthma: a Multiple Indicators Multiple Causes (MIMIC) model
AbstractKnowledge on multiple interdependences between quality of life (QoL) and behavioural problems in relation to asthma severity and control is undetermined. The aims of the study were: (i) to assess the relationship of QoL and behavioural problems with asthma severity and control (ii) to predict children’s “abnormal/borderline” status with variation in QoL. For these purposes a multicenter case-control study on 47 Severe Asthma (SA) and 94 Moderate Asthma (MA) children was performed. The MIMIC approach was applied to investigate the effect of SA and non-controlled asthma (NC) on QoL and behavioural disorders. Logistic regression was used to estimate probabilities of having an “abnormal…
Additional file 1: of A survey around the Italian pediatric units on current clinical practice for Sleep Disordered Breathing (SDB)
SleepPed questionnaire. (DOCX 48Â kb)
Issue 1 - “Update on adverse respiratory effects of outdoor air pollution”. Part 1): Outdoor air pollution and respiratory diseases: A general update and an Italian perspective
Objective: to summarize the main updated evidence about the health effects of air pollution and to focus on Italian epidemiological experiences on the respiratory effects. Results: The recent literature indicates that there is strong evidence for causal relationships between PM2.5 air pollution exposure and all-cause mortality as well as mortality from acute lower respiratory infections, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lung cancer. A growing body of evidence also suggests causal relationships with type II diabetes and impacts on neonatal mortality from low birth weight and short gestation as well as neurologic effects in both children and adults. …