0000000000075636
AUTHOR
Judith Murillo
Lack of association between proliferative verrucous leukoplakia and human papillomavirus infection.
Purpose To analyze proliferative verrucous leukoplakia (PVL) for the presence of human papillomavirus (HPV) in different stages of the disease. Materials and Methods We studied 13 patients with PVL. In 10 patients (76.9%), a lesional biopsy was taken and frozen at −40°C. Four patients were instructed to mouth rinse with sterile sera. The biopsy and rinse samples were analyzed for HPV by PCR. Results We did not detect HPV infection in the PVL tissue or in the oral rinse of any of the 13 patients in any stage of the disease analyzed, neither in oral squamous cell carcinoma nor in the simple hyperkeratosis. Conclusion There was no association between PVL and HPV infection in our patients.
Osteonecrosis of the jaws by intravenous bisphosphonates and osteoradionecrosis : a comparative study
Aims: We analyze the possible clinical differences between bone jaw exposed areas in ONJ (osteonecrosis of the jaws) and ORN (osteoradionecrosis). Patients and method: Group 1 was composed with 53 ONJ cases and group 2 with 20 ORN cases. In both groups we analyzed, the major size of the exposed bone areas, the number of exposed areas, the location on the jaws and the presence of others associated and severe complications, such as skin fistulas and jaw fractures. We also investigated the possible local aetiology or trigger factor of the lesions. Results: The major size of the bone exposed areas was 2.29±2.02(mean ± std.dev) in group 1 and 2.7±2.9 (mean ± std.dev) in group 2 (p>0.05). The num…
Malignant peripheral nerve sheath tumor of the maxila
Summary We present a case of a malignant peripheral nerve sheath tumor [MPNST] of the maxilla corresponding to a 12 year old male who had a painful, ulcerated rapid growing tumor. Histology revealed the presence of a tumor consisting of fusiform cells with abundant mitosis, with negative cytokeratins, actin, desmin, myoglobin and factor VIII. In contrast, the protein S-100 was positive. MPNST was not associated with signs of Neurofibromatosis Type 1. The patient was surgically intervened and received radiotherapy, then died within 10 months posterior to surgical intervention after suffering recurrence.
Oral microbiome in Proliferative Verrucous Leukoplakia exhibits loss of diversity and enrichment of pathogens.
Abstract Objectives Oral microbiome plays an important role in oral diseases. Among them, proliferative verrucous leucoplakia (PVL) is an uncommon form of progressive multifocal leukoplakia with a worryingly rate of malignant transformation. Here, we aimed to characterize the oral microbiome of PVL patients and compare it with those of healthy controls. Material and methods Oral biopsies from ten PVL patients and five healthy individuals were obtained and used to compare their microbial communities. The sequence of the V3-V4 region of 16S rRNA gene was used as the taxonomic basis to estimate and analyze the composition and diversity of bacterial populations present in the samples. Results O…
Intraoral Schwannomas: presentation of a series of 12 cases
Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:30:51Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:38:06Z : No. of bitstreams: 1 2-s2.0-84885114651.pdf: 427821 bytes, checksum: 6429b2f0fe956a3fa1d4acd1f8543e13 (MD5) Made available in DSpace on 2014-05-27T11:30:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-10-14 Introduction: Schwannomas are benign and not very frequent tumors of the peripheral nerves, derived from the nerve supporting Schwann cells. Study Design: Data were collected on the clinical manifestations (sex, age), location, size and symptonts of the lesions as well as the evolution time and the initial (presumption) …
Tercer molar mandibular ectópico en región subcondilar: caso clínico y revisión de la literatura
ResumenLa impactación de terceros molares en la región condilar es muy inusual. Este artículo describe el caso de cordal incluido en región subcondilar en una mujer que refirió dolor inespecífico hemifacial y varios episodios de tumefacción. Se describe el manejo quirúrgico de estas inclusiones y se realiza una revisión bibliográfica.AbstractEctopic impaction of the mandibular third molar in the condylar region is an extremely rare condition. This report describes a case of an impacted tooth in the sub-condylar region in a woman with hemifacial discomfort and recurrent swelling. A description of the surgical management of this pathology is given as well as a literatura review.