0000000000077126
AUTHOR
Stefan Krass
Importance of calibration for diameter and area determination by intravascular ultrasound
Intravascular ultrasound (IVUS) permits quantitative assessment of the lumen diameter and area of coronary arteries. The experimental study was performed to evaluate the accuracy of diameter and area measurements.Lumen quantitation (lumen diameter D and cross-sectional area A) in lucite tubes (lumen diameter 2.5 to 5.7 mm, Plexiglas) was performed using a mechanical IVUS system (HP console, 3.5 F catheter, Boston Scientific, 30 MHz). The influence of fluid type (blood, water and saline solution), fluid temperature (20 degrees C/37 degrees C), catheter to catheter variation, gain setting and ultrasound frequency (12, 20 and 30 MHz) was determined. In blood at 20 degrees C there was a constan…
Assessment of image quality of intracoronary ultrasound systems with tissue-equivalent vessel phantoms
Imaging of vascular structures by intracoronary ultrasound (ICUS) is finding more and more applications in coronary diagnosis and in the assessment of interventional access. The authors describe a method for easy and quick production of tissue-equivalent vessel phantoms from a special hydrocolloid. The mechanical tolerance is less than 3/100 mm. With these phantoms the authors tested the calibration and measured the resolution properties of the SONOS intravascular ultrasonic system (Hewlett Packard). The measurements revealed a slight space related underestimation of diameters up to 280 /spl mu/m. Using cross correlation and auto correlation functions the authors analyzed digitized ultrason…
Tissue classification by texture and spectral analysis of intracoronary ultrasound radio-frequency data
Imaging of vascular structures by intracoronary ultrasound allows in principal the recognition of different lesion types due to the echomorphology in the B-mode image. The subjective visual diagnosis is often difficult, especially the differentiation between thrombi and non-calcified plaque. The aim of this study was the extraction of features from the ultrasound radio-frequency signal for an objective characterization of coronary tissue. Methods of texture analysis and frequency analysis were used to differentiate red and white thrombi in vitro. Eight texture parameters of first and second order significantly differentiated red and white thrombi. The backscatter transfer function of red th…