showing 2 related works from this author
LbL multilayer capsules: recent progress and future outlook for their use in life sciences.
2010
In this review we provide an overview of the recent progress in designing composite polymer capsules based on the Layer-by-Layer (LbL) technology demonstrated so far in material science, focusing on their potential applications in medicine, drug delivery and catalysis. The benefits and limits of current systems are discussed and the perspectives on emerging strategies for designing novel classes of therapeutic vehicles are highlighted. © 2010 The Royal Society of Chemistry.
Ligand density on nanoparticles: A parameter with critical impact on nanomedicine
2019
Nanoparticles modified with ligands for specific targeting towards receptors expressed on the surface of target cells are discussed in literature towards improved delivery strategies. In such concepts the ligand density on the surface of the nanoparticles plays an important role. How many ligands per nanoparticle are best for the most efficient delivery? Importantly, this number may be different for in vitro and in vivo scenarios. In this review first viruses as "biological" nanoparticles are analyzed towards their ligand density, which is then compared to the ligand density of engineered nanoparticles. Then, experiments are reviewed in which in vitro and in vivo nanoparticle delivery has b…