0000000000079964

AUTHOR

Jingyu Zhang

showing 28 related works from this author

Synthesis of Polycyclic Indolines by Utilizing a Reduction/Cyclization Cascade Reaction

2021

European journal of organic chemistry 2021(45), 6097-6101 (2021). doi:10.1002/ejoc.202101191

Reduction (complexity)Acid catalysisCascade reactionChemistryddc:540Organic ChemistryPhysical and Theoretical Chemistry540Combinatorial chemistryEuropean Journal of Organic Chemistry
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Iron(III) Chloride as a Mild Catalyst for the Dearomatizing Cyclization of N-Acylindoles

2020

A catalytic approach for the preparation of indolines by dearomatizing cyclization is presented. FeCl3 acts as a catalyst to afford tetracyclic 5a,6-dihydro-12H-indolo[2,1-b][1,3]benzoxazin-12-ones in good yields. The cyclization also proceeds with tosylamides forming C-N bonds in 53% yield.

chemistry.chemical_compound010405 organic chemistryChemistryYield (chemistry)Organic Chemistry010402 general chemistry01 natural sciencesMedicinal chemistryIron(III) chloride0104 chemical sciencesCatalysisThe Journal of Organic Chemistry
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Synthesis of N‐Fused Indolines via Copper (II)‐Catalyzed Dearomatizing Cyclization of Indoles

2021

Advanced synthesis & catalysis 363(12), 3121-3126 (2021). doi:10.1002/adsc.202100290

aromaattiset yhdisteetkemiallinen synteesi660Chemistrychemistry.chemical_elementkupariGeneral ChemistryMedicinal chemistryCopperCatalysischemistry.chemical_compoundkatalyysiIndolineddc:660orgaaniset yhdisteet
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Cover Feature: Synthesis of Polycyclic Indolines by Utilizing a Reduction/Cyclization Cascade Reaction (Eur. J. Org. Chem. 45/2021)

2021

Reduction (complexity)Cascade reactionFeature synthesisComputational chemistryChemistryOrganic ChemistryCover (algebra)Physical and Theoretical ChemistryEuropean Journal of Organic Chemistry
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Iron(III) chloride as mild catalyst for the dearomatizing cyclization of N-acylindoles

2020

A catalytic approach for the preparation of indolines by dearomatizing cyclization is presented. FeCl3 acts as a catalyst to afford tetracyclic 5a,6-dihydro-12H-indolo[2,1-b][1,3]benzoxazin-12-ones in good yields. The cyclization also proceeds with tosylamides forming C-N bonds in 53 % yield. peerReviewed

katalyytitkemialliset yhdisteetkatalyysiorgaaninen kemiaindoliini
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Synthesis of Polycyclic Indolines utilizing a reduction/cyclization cascade reaction

2021

Subsequent reduction and dearomatizing cyclization reactions open up an entry into the synthesis of novel N-fused polycyclic indolines. The dearomatizing cyclization as key step of the sequence proceeds well with Cu(OTf)2 or TfOH as catalyst. At elevated temperature reduction of nitro-substituted precursors with iron under acidic conditions affords a broad variety of polycyclic indolines directly in a two-step cascade reaction in good to excellent yields. Using the developed protocol, the alkaloids Tryptanthrin and Phaitanthrin C have been prepared. peerReviewed

kemiallinen synteesicyclizationkatalyysinitrogen heterocyclescascade reactionshapetus-pelkistysreaktioorgaaniset yhdisteetacid catalysisdearomatization
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CCDC 1977489: Experimental Crystal Structure Determination

2020

Related Article: Jingyu Zhang, Jing Li, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, Markus Albrecht|2020|J.Org.Chem.|85|12160|doi:10.1021/acs.joc.0c01373

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters8-methyl-5a6-dihydro-12H-indolo[21-b][13]benzoxazin-12-oneExperimental 3D Coordinates
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CCDC 2067949: Experimental Crystal Structure Determination

2022

Related Article: Jingyu Zhang, Wei Xia, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Adv.Synth.Catal.|363|3121|doi:10.1002/adsc.202100290

Space GroupCrystallographyCrystal System5a-methyl-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1977492: Experimental Crystal Structure Determination

2020

Related Article: Jingyu Zhang, Jing Li, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, Markus Albrecht|2020|J.Org.Chem.|85|12160|doi:10.1021/acs.joc.0c01373

Space GroupCrystallographyCrystal System13415b-tetrahydro-2H10H-[13]benzoxazino[23-k]carbazol-10-oneCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1977495: Experimental Crystal Structure Determination

2020

Related Article: Jingyu Zhang, Jing Li, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, Markus Albrecht|2020|J.Org.Chem.|85|12160|doi:10.1021/acs.joc.0c01373

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters[2-(2-hydroxy-5-methylphenyl)-23-dihydro-1H-indol-1-yl](phenyl)methanoneExperimental 3D Coordinates
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CCDC 1977494: Experimental Crystal Structure Determination

2020

Related Article: Jingyu Zhang, Jing Li, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, Markus Albrecht|2020|J.Org.Chem.|85|12160|doi:10.1021/acs.joc.0c01373

Space GroupCrystallography5-(4-methylbenzene-1-sulfonyl)-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2067947: Experimental Crystal Structure Determination

2022

Related Article: Jingyu Zhang, Wei Xia, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Adv.Synth.Catal.|363|3121|doi:10.1002/adsc.202100290

Space GroupCrystallographyCrystal System8-methoxy-5-(4-methylbenzene-1-sulfonyl)-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2067946: Experimental Crystal Structure Determination

2022

Related Article: Jingyu Zhang, Wei Xia, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Adv.Synth.Catal.|363|3121|doi:10.1002/adsc.202100290

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates5-(4-nitrobenzene-1-sulfonyl)-5a6-dihydroindolo[21-b]quinazolin-12(5H)-one
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CCDC 1977488: Experimental Crystal Structure Determination

2020

Related Article: Jingyu Zhang, Jing Li, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, Markus Albrecht|2020|J.Org.Chem.|85|12160|doi:10.1021/acs.joc.0c01373

Space GroupCrystallography3-chloro-5a6-dihydro-12H-indolo[21-b][13]benzoxazin-12-oneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2067943: Experimental Crystal Structure Determination

2022

Related Article: Jingyu Zhang, Wei Xia, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Adv.Synth.Catal.|363|3121|doi:10.1002/adsc.202100290

Space GroupCrystallographyCrystal System5-(4-fluorobenzene-1-sulfonyl)-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2067948: Experimental Crystal Structure Determination

2022

Related Article: Jingyu Zhang, Wei Xia, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Adv.Synth.Catal.|363|3121|doi:10.1002/adsc.202100290

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters5a-methyl-5-(4-methylbenzene-1-sulfonyl)-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneExperimental 3D Coordinates
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CCDC 1977487: Experimental Crystal Structure Determination

2020

Related Article: Jingyu Zhang, Jing Li, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, Markus Albrecht|2020|J.Org.Chem.|85|12160|doi:10.1021/acs.joc.0c01373

Space GroupCrystallography2-methyl-5a6-dihydro-12H-indolo[21-b][13]benzoxazin-12-oneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1977491: Experimental Crystal Structure Determination

2020

Related Article: Jingyu Zhang, Jing Li, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, Markus Albrecht|2020|J.Org.Chem.|85|12160|doi:10.1021/acs.joc.0c01373

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters5a-phenyl-5a6-dihydro-12H-indolo[21-b][13]benzoxazin-12-oneExperimental 3D Coordinates
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CCDC 2080687: Experimental Crystal Structure Determination

2021

Related Article: Jingyu Zhang, Wei Xia, Meilin Qu, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Eur.J.Org.Chem.|2021|6097|doi:10.1002/ejoc.202101191

Space GroupCrystallographyCrystal System8-methoxy-5a-methyl-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1977486: Experimental Crystal Structure Determination

2020

Related Article: Jingyu Zhang, Jing Li, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, Markus Albrecht|2020|J.Org.Chem.|85|12160|doi:10.1021/acs.joc.0c01373

Space GroupCrystallographyCrystal System(2-hydroxyphenyl)(5-methyl-1H-indol-1-yl)methanoneCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2067945: Experimental Crystal Structure Determination

2022

Related Article: Jingyu Zhang, Wei Xia, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Adv.Synth.Catal.|363|3121|doi:10.1002/adsc.202100290

Space GroupCrystallographyCrystal System5-(4-iodobenzene-1-sulfonyl)-5a6-dihydroindolo[21-b]quinazolin-12(5H)-one ethyl acetate solvateCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2080689: Experimental Crystal Structure Determination

2021

Related Article: Jingyu Zhang, Wei Xia, Meilin Qu, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Eur.J.Org.Chem.|2021|6097|doi:10.1002/ejoc.202101191

Space GroupCrystallographyCrystal SystemCrystal Structure8-chloro-5a-methyl-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCell ParametersExperimental 3D Coordinates
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CCDC 2067944: Experimental Crystal Structure Determination

2022

Related Article: Jingyu Zhang, Wei Xia, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Adv.Synth.Catal.|363|3121|doi:10.1002/adsc.202100290

5-(4-chlorobenzene-1-sulfonyl)-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1977490: Experimental Crystal Structure Determination

2020

Related Article: Jingyu Zhang, Jing Li, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, Markus Albrecht|2020|J.Org.Chem.|85|12160|doi:10.1021/acs.joc.0c01373

Space GroupCrystallography9-methyl-5a6-dihydro-12H-indolo[21-b][13]benzoxazin-12-oneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2080691: Experimental Crystal Structure Determination

2021

Related Article: Jingyu Zhang, Wei Xia, Meilin Qu, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Eur.J.Org.Chem.|2021|6097|doi:10.1002/ejoc.202101191

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates5a-(4-chlorophenyl)-5a6-dihydroindolo[21-b]quinazolin-12(5H)-one
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CCDC 1977493: Experimental Crystal Structure Determination

2020

Related Article: Jingyu Zhang, Jing Li, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, Markus Albrecht|2020|J.Org.Chem.|85|12160|doi:10.1021/acs.joc.0c01373

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters28-dibromo-5a6-dihydro-12H-indolo[21-b][13]benzoxazin-12-oneExperimental 3D Coordinates
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CCDC 2080688: Experimental Crystal Structure Determination

2021

Related Article: Jingyu Zhang, Wei Xia, Meilin Qu, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Eur.J.Org.Chem.|2021|6097|doi:10.1002/ejoc.202101191

Space GroupCrystallography8-fluoro-5a-methyl-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2080690: Experimental Crystal Structure Determination

2021

Related Article: Jingyu Zhang, Wei Xia, Meilin Qu, Saskia Huda, Jas S. Ward, Kari Rissanen, Markus Albrecht|2021|Eur.J.Org.Chem.|2021|6097|doi:10.1002/ejoc.202101191

Space GroupCrystallography5a6-dimethyl-5a6-dihydroindolo[21-b]quinazolin-12(5H)-oneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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