0000000000082941

AUTHOR

Ian Purcell

showing 3 related works from this author

1-Year Outcomes of FFRCT-Guided Care in Patients With Suspected Coronary Disease

2016

Abstract Background Coronary computed tomographic angiography (CTA) plus estimation of fractional flow reserve using CTA (FFR CT ) safely and effectively guides initial care over 90 days in patients with stable chest pain. Longer-term outcomes are unknown. Objectives The study sought to determine the 1-year clinical, economic, and quality-of-life (QOL) outcomes of using FFR CT instead of usual care. Methods Consecutive patients with stable, new onset chest pain were managed by either usual testing (n = 287) or CTA (n = 297) with selective FFR CT (submitted in 201, analyzed in 177); 581 of 584 (99.5%) completed 1-year follow-up. Endpoints were adjudicated major adverse cardiac events (MACE) …

medicine.medical_specialtybusiness.industrymedicine.medical_treatmentFractional flow reserve030204 cardiovascular system & hematologymedicine.diseaseChest painRevascularization3. Good health030218 nuclear medicine & medical imagingCoronary artery disease03 medical and health sciences0302 clinical medicineQuality of lifeConventional PCIMedicineMyocardial infarctionRadiologymedicine.symptomCardiology and Cardiovascular MedicinebusinessMaceJournal of the American College of Cardiology
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Rationale and design of the Prospective LongitudinAl Trial of FFRCT: Outcome and Resource IMpacts study

2015

International audience; BACKGROUND: Fractional flow reserve (FFR) measured by coronary computed tomography angiography (FFRCT) has been validated against invasive FFR. However, there are no data on how the use of FFRCT affects patient care and outcomes. The aim of this study is to compare standard practice guided by usual care testing to FFRCT-guided management in symptomatic subjects with suspected coronary artery disease (CAD). METHODS: In this prospective nonrandomized trial, symptomatic patients with suspected CAD will be enrolled in 2 consecutive cohorts: a usual care-guided pathway (cohort 1) and an FFRCT-guided pathway (cohort 2). Each cohort is divided into 2 groups according to whe…

Malemedicine.medical_specialty*Tomography[SDV]Life Sciences [q-bio]Fractional flow reserveCoronary Artery DiseaseCoronary AngiographyCoronary Angiography/*methodsCoronary artery diseaseCoronary Artery Disease/*diagnosis/physiopathologyQuality of lifeRandomized Controlled Trials as Topic/*methodsPredictive Value of TestsMyocardial/*physiologyOutcome Assessment Health CareClinical endpointMedicineHumansProspective StudiesProspective cohort studyRandomized Controlled Trials as TopicAgedbusiness.industryMiddle Agedmedicine.diseaseFractional Flow Reserve3. Good healthX-Ray ComputedFractional Flow Reserve MyocardialStenosisPredictive value of testsCohortFemaleRadiologyOutcome Assessment (Health Care)/*methodsCardiology and Cardiovascular MedicinebusinessTomography X-Ray ComputedFollow-Up Studies
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Quality-of-Life and Economic Outcomes of Assessing Fractional Flow Reserve With Computed Tomography Angiography: PLATFORM.

2015

International audience; BACKGROUND: Fractional flow reserve estimated using computed tomography (FFRCT) might improve evaluation of patients with chest pain. OBJECTIVES: The authors sought to determine the effect on cost and quality of life (QOL) of using FFRCT instead of usual care to evaluate stable patients with symptoms suspicious for coronary disease. METHODS: Symptomatic patients without known coronary disease were enrolled into 2 strata based on whether invasive or noninvasive diagnostic testing was planned. In each stratum, consecutive observational cohorts were evaluated with either usual care or FFRCT. The number of diagnostic tests, invasive procedures, hospitalizations, and medi…

Malemedicine.medical_specialtycost comparisonVisual analogue scale*Fractional Flow Reserve[SDV]Life Sciences [q-bio]Fractional flow reserveCoronary Artery Disease030204 cardiovascular system & hematologyChest painCoronary Angiography030218 nuclear medicine & medical imagingCoronary artery diseaseAnginaCohort Studiesquality of life03 medical and health sciencesCoronary Artery Disease/*economics/*radiography/therapy0302 clinical medicineQuality of lifeEQ-5DmedicineHumansLongitudinal StudiesProspective StudiesMyocardial/physiologyTomographyComputed tomography angiography*Quality of Lifemedicine.diagnostic_testbusiness.industryX-Ray Computed/*economicsMiddle Agedmedicine.diseaseCoronary Angiography/*economics3. Good healthFractional Flow Reserve MyocardialTreatment OutcomePhysical therapyQuality of Lifestress testFemalemedicine.symptombusinessCardiology and Cardiovascular MedicineTomography X-Ray Computedmyocardial fractional flow reserveJournal of the American College of Cardiology
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