0000000000083908

AUTHOR

Nunziata Barbera

showing 2 related works from this author

Toxicological investigations in a fatal and non-fatal accident due to hydrogen sulphide (H2S)poisoning

2019

Hydrogen sulphide (H2S) is one of the most toxic natural gas and represents a not rare cause of fatal events in workplaces. We report here a serious accidental poisoning by hydrogen sulphide inhalation involving six sailors. Three of them died while the other three survived and were transported to the emergency room. No greenish discolouration of the body, that could be a feature of these type of deaths, was observed at autopsy. Given that blood and/or urine H2S detection does not allow to discriminate if it is related to inhalation or to putrefactive processes, the determination of thiosulphate, H2S main metabolite, is decisive. The succession of fatal events reported here can be rebuilt b…

MaleTime FactorsPoison controlAutopsyFatal accidentBrain EdemaUrine01 natural scienceschemistry.chemical_compound0302 clinical medicineThiosulfateHydrogen sulphideMedicineHydrogen SulfideThiosulfateAir PollutantsOccupational accidentInhalationFatal poisoningMiddle AgedPulmonary edemaFatal poisoning; Hydrogen sulphide; Non-fatal poisoning; Occupational accident; Thiosulphate; Administration Inhalation; Adult; Air Pollutants; Brain Edema; Emphysema; Humans; Hydrogen Sulfide; Hyperemia; Italy; Male; Middle Aged; Military Personnel; Pulmonary Edema; Thiosulfates; Time Factors; Accidents OccupationalOccupationalMilitary PersonnelInhalationItalyAir PollutantAnesthesiaAdministrationNon-fatal poisoningHumanAdultTime FactorThiosulphateThiosulfatesHyperemiaPulmonary EdemaHydrogen sulphidePathology and Forensic Medicine03 medical and health sciencesAdministration InhalationHumansAccidents Occupational030216 legal & forensic medicineEmphysemabusiness.industry010401 analytical chemistrymedicine.disease0104 chemical scienceschemistryAccidentsbusinessLaw
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The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome

2013

The purpose of the present study is to determine the role of lidocaine, caffeine and dextromethorphan, used as adulterant substances, in five cases of drug overdose which have come to our attention. Taking into account the pharmacological mechanism, blood concentration and route of administration (intravenous) we evaluated the hypothesis that these substances could act with a synergistic effect - or at least additive - with the illicit drugs on the central nervous system and cardiovascular system.

MalePyrrolidinesDrug ContaminationLidocainePharmacologyKidneyDextromethorphanDrug Userschemistry.chemical_compoundBileAnesthetics LocalForensic PathologyLungAdulterantMorphineDextromethorphanGastrointestinal ContentsLiverFemaleDrug ContaminationCaffeineSelective Serotonin Reuptake Inhibitorsmedicine.drugAdultNarcoticsSubstance-Related DisordersCitalopramDrug overdosePathology and Forensic MedicineForensic ToxicologyRoute of administrationAdulterantsCaffeinemedicineHumansBrain ChemistryMorphine DerivativesCodeineIllicit Drugsbusiness.industryForensic toxicologyAdulterants Lidocaine Caffeine DextromethorphanLidocainemedicine.diseaseVitreous BodyAntitussive AgentschemistryCentral Nervous System StimulantsDrug OverdosebusinessLawMethadoneForensic Science International
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