0000000000084823

AUTHOR

Ingrid Demmelmaier

0000-0002-2068-4708

showing 17 related works from this author

Long-term resource utilisation and associated costs of exercise during (neo)adjuvant oncological treatment: the Phys-Can project

2022

Background Exercise during oncological treatment is beneficial to patient health and can counteract the side effects of treatment. Knowledge of the societal costs associated with an exercise intervention, however, is limited. The aims of the present study were to evaluate the long-term resource utilisation and societal costs of an exercise intervention conducted during (neo)adjuvant oncological treatment in a randomised control trial (RCT) versus usual care (UC), and to compare high-intensity (HI) versus low-to-moderate intensity (LMI) exercise in the RCT. Methods We used data from the Physical Training and Cancer (Phys-Can) project. In the RCT, 577 participants were randomised to HI or to …

Hälso- och sjukvårdsorganisation hälsopolitik och hälsoekonomiCancer; exercise; health care costs; sick leave; costs; cost analysisCost-Benefit Analysiscostssick leavecost analysisNeoplasmshealth care costsHumansRadiology Nuclear Medicine and imagingSjukgymnastikExercisePhysiotherapyPhysical Therapy ModalitiesCancerCancer och onkologiexerciseResistance TrainingHematologyGeneral MedicineHealth Care Service and Management Health Policy and Services and Health EconomyHealth ServicesVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762OncologyCancer and OncologyQuality of Life
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Exercise intensity and markers of inflammation during and after (neo-) adjuvant cancer treatment.

2021

Exercise training has been hypothesized to lower the inflammatory burden for patients with cancer, but the role of exercise intensity is unknown. To this end, we compared the effects of high-intensity (HI) and low-to-moderate intensity (LMI) exercise on markers of inflammation in patients with curable breast, prostate and colorectal cancer undergoing primary adjuvant cancer treatment in a secondary analysis of the Phys-Can randomized trial (NCT02473003). Sub-group analyses focused on patients with breast cancer undergoing chemotherapy. Patients performed 6 months of combined aerobic and resistance exercise on either HI or LMI during and after primary adjuvant cancer treatment. Plasma taken …

0301 basic medicineMaleCancer Researchmedicine.medical_specialtyColorectal cancerEndocrinology Diabetes and Metabolismmedicine.medical_treatmentBreast NeoplasmsGastroenterologylaw.invention03 medical and health sciences0302 clinical medicineEndocrinologyBreast cancerRandomized controlled triallawProstateInternal medicinemedicineHumansExerciseInflammationChemotherapybiologybusiness.industryC-reactive proteinCancermedicine.diseaseExercise Therapy030104 developmental biologymedicine.anatomical_structureOncology030220 oncology & carcinogenesisExercise intensitybiology.proteinFemalebusinessBiomarkersEndocrine-related cancer
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Patterns and determinants of adherence to resistance and endurance training during cancer treatment in the Phys-Can RCT.

2022

Abstract Background Knowledge regarding adherence is necessary to improve the specificity of exercise interventions during cancer treatment. We aimed to determine adherence to resistance and endurance training interventions in parallel; identify subgroups with similar adherence characteristics; and examine determinants of these subgroups. Methods In the Phys-Can randomised controlled trial, participants (n = 577, 81% women, mean(SD) age 59(12) years, and 50% with BMI ≥ 25 kg/m2) starting (neo-) adjuvant treatment for breast, colorectal or prostate cancer were randomized to 6-month of high (HI) or low-to-moderate intensity (LMI) supervised, group-based resistance training and individual home…

IdrottsvetenskapRehabilitationPhysical Therapy Sports Therapy and RehabilitationResistance trainingEndurance trainingTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]All institutes and research themes of the Radboud University Medical CenterAdherenceFITT principlesOrthopedics and Sports MedicineVDP::Medisinske Fag: 700PatternsExerciseDeterminantsSport and Fitness SciencesCancerBMC sports science, medicinerehabilitation
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Exercise Adherence and Effect of Self-Regulatory Behavior Change Techniques in Patients Undergoing Curative Cancer Treatment: Secondary Analysis from…

2020

Introduction: Adherence to exercise interventions in patients with cancer is often poorly described. Further, it is unclear if self-regulatory behavior change techniques (BCTs) can improve exercise adherence in cancer populations. We aimed to (1) describe exercise adherence in terms of frequency, intensity, time, type (FITT-principles) and dropouts, and (2) determine the effect of specific self-regulatory BCTs on exercise adherence in patients participating in an exercise intervention during curative cancer treatment. Methods: This study was a secondary analysis using data from a Swedish multicentre RCT. In a 2×2 factorial design, 577 participants recently diagnosed with curable breast, col…

Malemedicine.medical_specialtyadjuvant treatmentexercise prescriptionphysical activitylcsh:RC254-282law.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawBehavior TherapySecondary analysismedicineHumansIn patientadherenceSjukgymnastikExercisePhysiotherapySport and Fitness Sciencesbusiness.industryIdrottsvetenskapbehavioral interventionCancerProstatic NeoplasmsBehavior change methodsResistance Training030229 sport scienceslcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaseCancer treatmentPeer reviewExercise TherapyComplementary and alternative medicineVDP::Medisinske Fag: 700::Helsefag: 800030220 oncology & carcinogenesisExercise and Cancer TreatmentoncologyPhysical therapyExercise prescriptionbusinessResearch Articlebehavior change support
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Motivation for physical activity in adolescents with asthma

2020

Objective: We explored motivation for physical activity (PA) and exercise in adolescents with asthma who entered and continued a 10-week play-based exercise intervention. Methods: Eighteen adolescents with asthma, aged 13–17 years, participated in a 10-week play- and interval-based indoor exercise intervention during winter and autumn months. Semi-structured focus group interviews were conducted in weeks 2 and 8, focusing on motivation for PA and exercise, as well as field observations of exercise sessions in weeks 2, 6, and 8. The first interview was analyzed separately from the second one and descriptive observational data were obtained using thematic analysis and self-determination theor…

MalePulmonary and Respiratory MedicineAdolescentbarriersRespiratory Medicine and AllergyPhysical activity03 medical and health sciences0302 clinical medicinemedicineHumansobstructive lung diseaseImmunology and Allergy030212 general & internal medicineExerciseSport and Fitness SciencesLungmedicin och allergiAsthmaMotivationyouthIdrottsvetenskapbusiness.industrySocial SupportFocus Groupsmedicine.diseaseFocus groupAsthmaObstructive lung diseaseExercise TherapyPeer reviewVDP::Medisinske Fag: 700::Helsefag: 800030228 respiratory systemPediatrics Perinatology and Child Healthfocus groupsFemaleSeasonsplaybusinessqualitative researchQualitative researchClinical psychologyJournal of Asthma
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Additional file 1 of Effect of self-regulatory behaviour change techniques and predictors of physical activity maintenance in cancer survivors: a 12-…

2021

Additional file 1: Suppl Table 1. Physical activity maintenance at 12-month follow-up and baseline characteristics of participants included vs. excluded from the predictor analyses.

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Lifestyle and Empowerment Techniques in Survivorship of Gynaecologic Oncology (LETSGO study): A study protocol for a multicentre longitudinal interve…

2021

IntroductionThe number of gynaecological cancer survivors is increasing and there is a need for a more sustainable model of follow-up care. Today’s follow-up model is time-consuming and patients have reported unmet needs regarding information about their cancer and strategies for managing the consequences of treatment. The main aim of this study is to assess health-related empowerment—in terms of patient education, psychosocial support, and promotion of physical activity—in a new follow-up model by comparing it to standard follow-up in a quasi-randomised study involving intervention hospitals and control hospitals.Methods and analysisAt the intervention hospitals, patients will be stratifie…

protocols & guidelinesSurvivorship0302 clinical medicineinformation technologyHealth careMulticenter Studies as Topichealth economics030212 general & internal medicine1506Empowermentmedia_commonBiological Specimen BanksRandomized Controlled Trials as TopicRHealth technologyPublic Health Global Health Social Medicine and EpidemiologyGeneral MedicineBiobankOncologyVDP::Medisinske Fag: 700::Helsefag: 800030220 oncology & carcinogenesisCancer treatmentMedicineFemale1717Hälso- och sjukvårdsorganisation hälsopolitik och hälsoekonomimedicine.medical_specialtyGenital Neoplasms Femalemedia_common.quotation_subjectHealth-related empowermentBiomedical Technologyquality in health care03 medical and health sciencesQuality of life (healthcare)medicineHumansLife StyleConsequencesGynaecological cancerHealth economicsbusiness.industryVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Oncology: 762gynaecological oncologychange managementRepeated measures designHealth Care Service and Management Health Policy and Services and Health EconomyVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762Folkhälsovetenskap global hälsa socialmedicin och epidemiologiFamily medicineQuality of LifeFollow-up careNeoplasm Recurrence LocalbusinessPatient education
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Additional file 1 of Does inflammation markers or treatment type moderate exercise intensity effects on changes in muscle strength in cancer survivor…

2023

Additional file 1. Supplementary Table 1. Baseline characteristics of participants included in the analysis vs. participants not included.

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Design of a randomized controlled trial of physical training and cancer ( Phys-Can) the impact of exercise intensity on cancer related fatigue, quali…

2017

Background: Cancer-related fatigue is a common problem in persons with cancer, influencing health-related quality of life and causing a considerable challenge to society. Current evidence supports the beneficial effects of physical exercise in reducing fatigue, but the results across studies are not consistent, especially in terms of exercise intensity. It is also unclear whether use of behaviour change techniques can further increase exercise adherence and maintain physical activity behaviour. This study will investigate whether exercise intensity affects fatigue and health related quality of life in persons undergoing adjuvant cancer treatment. In addition, to examine effects of exercise …

MaleQuality of lifeCancer Researchmedicine.medical_specialtyActivities of daily livingBreast NeoplasmsPhysical exerciselcsh:RC254-282law.inventionStudy Protocol03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationQuality of life (healthcare)Cancer SurvivorsRandomized controlled trialEndurance traininglawBehaviour change techniquesGeneticsmedicineHumans030212 general & internal medicineCancer-related fatigueFatigueCancerCancer och onkologibusiness.industryCancer; Physical exercise; Behaviour change techniques; Fatigue; Biological mechanism; Quality of life; Randomized controlled trialProstatic NeoplasmsPhysical exerciseBiological mechanismlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensExercise TherapyMoodOncologyPhysical FitnessRandomized controlled trial030220 oncology & carcinogenesisCancer and OncologyExercise intensityPhysical therapyFemalemedicine.symptomColorectal Neoplasmsbusiness
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Comparison between logbook-reported and objectively-assessed physical activity and sedentary time in breast cancer patients: an agreement study

2017

BACKGROUND: Increasing physical activity (PA) and decreasing sedentary time (ST) have important health effects among breast cancer patients, a growing population group. PA and sedentary behaviors are complex multi-dimensional behaviors and are challenging to monitor accurately. To date few studies have compared self-reports and objective measurement in assessing PA and ST in women undergoing breast cancer treatments. The aim of the present study was to compare self-reports and objective measures for assessing daily time spent in moderate-intensity physical activity (MPA), vigorous-intensity physical activity (VPA) and ST in women undergoing breast cancer treatments. METHODS: Baseline data f…

medicine.medical_specialtySports medicinePopulationSedentary lifestylePhysical activityPhysical Therapy Sports Therapy and Rehabilitation03 medical and health sciences0302 clinical medicineBreast cancerMedicineOrthopedics and Sports MedicineSjukgymnastiklcsh:Sports medicineeducationPhysiotherapyExerciseRank correlationSedentary lifestyleSedentary timeeducation.field_of_studyMeasurement accuracybusiness.industryRehabilitation030229 sport sciencesmedicine.diseaseActivity monitor030220 oncology & carcinogenesisPhysical therapyBreast neoplasmslcsh:RC1200-1245businessLogbookResearch ArticleBMC Sports Science, Medicine and Rehabilitation
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Effect of self-regulatory behaviour change techniques and predictors of physical activity maintenance in cancer survivors: a 12-month follow-up of th…

2021

Abstract Background Current knowledge about the promotion of long-term physical activity (PA) maintenance in cancer survivors is limited. The aims of this study were to 1) determine the effect of self-regulatory BCTs on long-term PA maintenance, and 2) identify predictors of long-term PA maintenance in cancer survivors 12 months after participating in a six-month exercise intervention during cancer treatment. Methods In a multicentre study with a 2 × 2 factorial design, the Phys-Can RCT, 577 participants with curable breast, colorectal or prostate cancer and starting their cancer treatment, were randomized to high intensity exercise with or without self-regulatory behaviour change technique…

MaleCancer ResearchTime FactorsCancer survivorsLogistic regressionBody Mass Indexlaw.inventionTobacco UseProstate cancerRandomized controlled trialBehavior TherapylawOdds RatioMedicineRC254-282DeterminantsHigh intensityNeoplasms. Tumors. Oncology. Including cancer and carcinogensBehaviour changeMiddle AgedBehavioural supportEndurance TrainingVDP::Medisinske Fag: 700::Helsefag: 800OncologySelf-regulationRegression AnalysisFemaleColorectal NeoplasmsMonth follow upmedicine.medical_specialtyBehaviour changeMaintenancePhysical activityBreast NeoplasmsSelf-ControlConfidence IntervalsGeneticsHumansExerciseSwedenMotivationCancer och onkologibusiness.industryResearchProstatic NeoplasmsCancerResistance Trainingmedicine.diseaseActigraphyCancer and OncologyQuality of LifePhysical therapybusinessFollow-Up StudiesBMC Cancer
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Exercise during and after curative oncological treatment – a mapping review

2016

Background: By mapping the existing literature on exercise oncology, gaps in knowledge can be identified, and future directions for research can be pointed out.Objectives: This review aimed to map diagnoses and outcome measures targeted in reviews and describe the effects on those outcomes. Further, the aim was to map exercise intervention characteristics being reviewed and the effects depending on these characteristics, and to discuss implications for future research.Methods: A systematic search was performed in PubMed, Cinahl, PSYCHInfo, and Cochrane Library. Reviews including physical activity and exercise intervention trials in adult patients during or after curative oncological treatme…

medicine.medical_specialtyExercise interventionbusiness.industryRehabilitationPhysical fitnessAlternative medicineOutcome measuresPhysical activityPhysical Therapy Sports Therapy and RehabilitationCINAHLCochrane Library03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesismedicinePhysical therapyOrthopedics and Sports Medicine030212 general & internal medicineMedical diagnosisbusinessPhysical Therapy Reviews
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Who makes it all the way? Participants vs. decliners, and completers vs. drop-outs, in a 6-month exercise trial during cancer treatment : Results fro…

2022

Abstract Purpose To compare sociodemographic, health- and exercise-related characteristics of participants vs. decliners, and completers vs. drop-outs, in an exercise intervention trial during cancer treatment. Methods Patients with newly diagnosed breast, prostate, or colorectal cancer were invited to participate in a 6-month exercise intervention. Background data for all respondents (n = 2051) were collected at baseline by questionnaire and medical records. Additional data were collected using an extended questionnaire, physical activity monitors, and fitness testing for trial participants (n = 577). Moreover, a sub-group of decliners (n = 436) consented to additional data collection by a…

Malemedicine.medical_specialtyColorectal cancerPhysical activitylaw.inventionRandomized controlled triallawNeoplasmsSurveys and QuestionnairesAttritionmedicineÖvrig annan medicin och hälsovetenskapHumansExerciseSport and Fitness SciencesBehaviorCognitive Behavioral TherapyVDP::Medical disciplines: 700::Clinical medical disciplines: 750business.industryPhysical activityIdrottsvetenskapMedical recordFitness TestingPhysical activity; Oncology; Recruitment; Behavior; Health psychology; Attritionmedicine.diseaseOther Medical Sciences not elsewhere specifiedExercise TherapyCancer treatmentHealth psychologyHealth psychologyOncologyQuality of LifePhysical therapyAnxietyFemaleOriginal ArticleRecruitmentmedicine.symptombusiness
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"Finding my own motivation" - A Mixed Methods Study of Exercise and Behaviour Change Support During Oncological Treatment

2019

AbstractBackgroundExercising during oncological treatment is beneficial but challenging for persons with cancer and may require strategies to increase motivation. Behaviour change support, including specific behaviour change techniques (BCTs), have been used to facilitate exercise in persons undergoing oncological treatment, but more detailed knowledge from an individual perspective is needed to inform clinical practice. The aims were to explore the motivational experiences of exercise combined with behaviour change support, and to describe how specific BCTs were valued among persons exercising during oncological treatment.MethodsA mixed-methods study was conducted using semi-structured int…

MalePsychotherapistBehaviour changePhysical activityArticle03 medical and health sciences0302 clinical medicineBehavior TherapyNeoplasmsSurveys and QuestionnairesBehaviour change techniquesQualitative researchIncentivesHumans030212 general & internal medicineSjukgymnastikExercisePhysiotherapyApplied PsychologySelf-determination theoryAgedCancerMotivationCancer och onkologiPhysical activitySocial SupportMiddle AgedPeer reviewSelf-determination theoryVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762Health psychologyIncentive030220 oncology & carcinogenesisCancer and OncologyFemalePsychologyQualitative research
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Does exercise intensity matter for fatigue during (neo-)adjuvant cancer treatment? The Phys-Can randomized clinical trial

2021

Exercise during cancer treatment improves cancer-related fatigue (CRF), but the importance of exercise intensity for CRF is unclear. We compared the effects of high- vs low-to-moderate-intensity exercise with or without additional behavior change support (BCS) on CRF in patients undergoing (neo-)adjuvant cancer treatment. This was a multicenter, 2x2 factorial design randomized controlled trial (Clinical Trials NCT02473003) in Sweden. Participants recently diagnosed with breast (n = 457), prostate (n = 97) or colorectal (n = 23) cancer undergoing (neo-)adjuvant treatment were randomized to high intensity (n = 144), low-to-moderate intensity (n = 144), high intensity with BCS (n = 144) or low…

MaleAnxiety030204 cardiovascular system & hematologyNeo adjuvantlaw.inventionTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]0302 clinical medicineRandomized controlled trialBehavior TherapylawNeoplasmsActivities of Daily LivingOrthopedics and Sports MedicineSjukgymnastikPhysiotherapyCancer-related fatigueLicenseFatigueDepressionCreative commonsMiddle AgedVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850Neoadjuvant TherapyExercise TherapyCancer treatmentEndurance TrainingCardiorespiratory FitnessVDP::Medisinske Fag: 700::Helsefag: 800Femalemedicine.symptomColorectal NeoplasmsPsychologybehavior change; cancer‐ related fatigue; endurance training; oncology; resistance trainingmedicine.medical_specialtyBreast NeoplasmsPhysical Therapy Sports Therapy and Rehabilitation03 medical and health sciencesmedicineHumansMuscle StrengthCancer och onkologiResistance trainingProstatic NeoplasmsResistance Training030229 sport sciencesCancer and OncologyQuality of LifeExercise intensityPhysical therapySedentary BehaviorSleep
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Does inflammation markers or treatment type moderate exercise intensity effects on changes in muscle strength in cancer survivors participating in a …

2023

Abstract Background Resistance exercise has a beneficial impact on physical function for patients receiving oncological treatment. However, there is an inter-individual variation in the response to exercise and the tolerability to high-intensity exercise. Identifying potential moderating factors, such as inflammation and treatment type, for changes in muscle strength is important to improve the effectiveness of exercise programs. Therefore, we aimed to investigate if inflammation and type of oncological treatment moderate the effects of exercise intensity (high vs. low-moderate) on muscular strength changes in patients with breast (BRCA) or prostate cancer (PRCA). Methods Participants with …

InflammationCancer och onkologiIdrottsvetenskapRehabilitationModeratorsPhysical Therapy Sports Therapy and RehabilitationAndrogen deprivation therapyVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850Resistance trainingCancer and OncologyChemotherapyOrthopedics and Sports MedicineAndrogen deprivation therapy; Cancer; Chemotherapy; Exercise intensity; Moderators; Inflammation; Resistance trainingExercise intensitySport and Fitness SciencesCancer
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The Phys-Can observational study: adjuvant chemotherapy is associated with a reduction whereas physical activity level before start of treatment is a…

2020

AbstractBackgroundAdjuvant therapy may cause multiple sideeffects on long term health, including reduced cardiorespiratory fitness (CRF) in patients with breast cancer (1, 2). However, there is currently limited knowledge regarding the effect of different types of adjuvant cancer treatment on CRF in other cancer populations. The primary objective of the present study was to assess whether previously known correlates (age, diagnosis, initial CRF, physical activity level), type of adjuvant treatment and cancer-related fatigue were associated with changes in$$ \dot{V}{O}_2\mathit{\max} $$V̇O2maxin patients with breast, prostate or colorectal cancer.MethodsProspective study with two time points…

medicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationType (model theory)GastroenterologyIncremental exercise03 medical and health sciences0302 clinical medicineBreast cancerInternal medicinemedicineAdjuvant therapyOrthopedics and Sports Medicine030212 general & internal medicinelcsh:Sports medicineProspective cohort studyCancer-related fatigueCancer related fatigueOncological treatmentPhysical activitybusiness.industryRehabilitationVO2 maxPublic Health Global Health Social Medicine and Epidemiology030229 sport sciencesVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850medicine.diseaseConfidence intervalCardiopulmonary exercise testingFolkhälsovetenskap global hälsa socialmedicin och epidemiologimedicine.symptomlcsh:RC1200-1245businessResearch ArticleBMC Sports Science, Medicine and Rehabilitation
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