0000000000085494

AUTHOR

Andrea De Maria

showing 2 related works from this author

CD4saurus Rex & HIVelociraptor vs. development of clinically useful immunological markers: a Jurassic tale of frozen evolution.

2011

Abstract One of the most neglected areas of everyday clinical practice for HIV physicians is unexpectedly represented by CD4 T cell counts when used as an aid to clinical decisions. All who care for HIV patients believe that CD4+ T cell counts are a reliable method to evaluate a patient immune status. There is however a fatalistic acceptance that besides its general usefulness, CD4+ T cell counts have relevant clincal and immunological limits. Shortcomings of CD4 counts appear in certain clinical scenarios including identification of immunological nonresponders, subsequent development of cancer on antiretroviral teatment, failure on tretment simplification. Historical and recently described…

medicine.medical_specialtyT cellantiviral treatmentHuman immunodeficiency virus (HIV)lcsh:MedicineHIV; AIDS; CD4Diseasemedicine.disease_causeGeneral Biochemistry Genetics and Molecular BiologyCD4+T cellsImmune systemAcquired immunodeficiency syndrome (AIDS)medicineIntensive care medicineMedicine(all)clinical trialsImmune statusBiochemistry Genetics and Molecular Biology(all)business.industrylcsh:RCancerimmune reconstitutionGeneral Medicinemedicine.diseaseClinical trialmedicine.anatomical_structureImmunologyCommentarybusiness
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Editorial debate: Challenges we oncologists, working within a universal healthcare system, have to face in these hard times

2020

I have been very much impressed by the clarity, pragmatism and good medical judgement of the article by Camilo Porta,1 a respected and dedicated ESMO faculty member and friend, giving his personal perspective on real issues many oncologists working in a public system are eventually facing during the SARS-CoV-2 pandemic. I understand Professor Porta is voicing what many oncologists from countries deeply affected by the pandemic, such as Italy or Spain, may think. Although I concur with most of his approaches and comments, I would like to complement some of these statements with some additional thoughts. Medicine was created more than 2500 years ago as a profession aiming at alleviating suffe…

PragmatismCancer Researchbusiness.industrySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)media_common.quotation_subjectPerspective (graphical)JudgementFace (sociological concept)Public relationslcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogenslcsh:RC254-282law.inventionOncologylawPolitical sciencePandemicCLARITYbusinessmedia_commonHealthcare systemESMO Open
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