0000000000085506

AUTHOR

Miriam Guitart

showing 4 related works from this author

Discoidin domain receptor 1 gene variants are associated with decreased white matter fractional anisotropy and decreased processing speed in schizoph…

2019

Abstract DDR1 has been linked to schizophrenia (SZ) and myelination. Here, we tested whether DDR1 variants in people at risk for SZ influence white matter (WM) structural variations and cognitive processing speed (PS). First, following a case-control design (Study 1), SZ patients (N = 1193) and controls (N = 1839) were genotyped for rs1264323 and rs2267641 at DDR1, and the frequencies were compared. We replicated the association between DDR1 and SZ (rs1264323, adjusted P = 0.015). Carriers of the rs1264323AA combined with the rs2267641AC or CC genotype are at risk to develop SZ compared to the other genotype combinations. Second, SZ patients (Study 2, N = 194) underwent an evaluation of PS …

AdultMalemedicine.medical_specialtyTrail Making TestBiologyPolymorphism Single NucleotideWhite matter03 medical and health sciences0302 clinical medicineDiscoidin Domain Receptor 1Internal medicineGenotypeFractional anisotropymedicineHumansCognitive DysfunctionGenotypingBiological PsychiatryDDR1Middle Agedmedicine.diseaseMagnetic Resonance ImagingWhite Matter030227 psychiatryPsychiatry and Mental healthmedicine.anatomical_structureEndocrinologySchizophreniaSpainCase-Control StudiesSchizophreniaFemale030217 neurology & neurosurgeryDiscoidin domainJournal of psychiatric research
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Research Letter: is neuroticism a risk factor for postpartum depression?

2012

Although the relationship between personality and depressive illness is complex (Shea, 2005), there is empirical evidence that some personality features such as neuroticism, harm avoidance, introversion, dependency, self-criticism or perfectionism are related to depressive illness risk (Gunderson et al. 1999). Moreover, personality traits, especially neuroticism, may explain the increased prevalence of depression among females (Goodwin & Gotlib, 2004). Few studies have explored neuroticism, extraversion and psychoticism as risk factors for depression after an event as stressful as childbirth. Pitt (1968) was the first author to report high scores on neuroticism and low scores on extraversio…

Postpartum depressionNeurotic DisordersDepresión postpartoEvaluación de la personalidad:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]medicine.disease_causePersonality Assessment:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]PregnancyRisk Factors62P ApplicationsBig Five personality traits:Psychiatry and Psychology::Mental Disorders::Neurotic Disorders [Medical Subject Headings]Applied Psychology:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings]education.field_of_studyPerfectionism (psychology)Middle AgedNeuroticismPsychiatry and Mental healthMathematical statistics:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Logistic Models [Medical Subject Headings]:Named Groups::Persons::Age Groups::Adolescent [Medical Subject Headings]Harm avoidanceFemaleEstudios de seguimientoPsychology:Psychiatry and Psychology::Behavioral Disciplines and Activities::Personality Assessment [Medical Subject Headings]Factores de riesgoAdultmedicine.medical_specialtyAdolescent:Named Groups::Persons::Age Groups::Adult::Young Adult [Medical Subject Headings]PopulationEstadísticaDepression PostpartumYoung AdultPsychoticismCorrespondence:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Follow-Up Studies [Medical Subject Headings]medicine:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]Humans:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychiatric Status Rating Scales [Medical Subject Headings]Escalas de valoración psiquiátricaPsychiatryeducationPsychiatric Status Rating ScalesExtraversion and introversion:Matemàtiques i estadística::Estadística aplicada::Estadística biosanitària [Àrees temàtiques de la UPC]:Psychiatry and Psychology::Mental Disorders::Mood Disorders::Depressive Disorder::Depression Postpartum [Medical Subject Headings]medicine.diseaseLogistic Models:Check Tags::Female [Medical Subject Headings]Trastornos neuróticosFollow-Up Studies
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Association study of 44 candidate genes with depressive and anxiety symptoms in post-partum women.

2009

The post-partum period is a time of extreme vulnerability for a whole spectrum of psychiatric disorders. Delivery may be considered an important risk factor in genetically susceptible women. Five hundred and eight SNPs in 44 genes at candidate pathways putatively related to mood changes after delivery were genotyped in a multicenter cohort of 1804 women from Spain. Participants completed two scales at 2-3 days, 8 weeks, and 32 weeks post-partum, the Edinburgh Post-partum Depression Scale (EPDS) and the Spielberger State-Trait Anxiety Inventory (STAI). Those women who scored 9 or more on EPDS were evaluated for major depression using the Diagnostic Interview for Genetics Studies (DIGS) adapt…

Candidate genemedicine.medical_specialtyTime FactorsGenotypeAnxietyPolymorphism Single NucleotideWhite PeopleCohort StudiesDepression PostpartumInternal medicinePost-hoc analysisProtein Kinase C betamedicineHumansPsychiatryBiological PsychiatrySerotonin transporterDepression (differential diagnoses)Protein Kinase CRetrospective StudiesPsychiatric Status Rating ScalesSerotonin Plasma Membrane Transport ProteinsbiologyPostpartum PeriodRepeated measures designPsychiatry and Mental healthMoodSpainCohortbiology.proteinDopa DecarboxylaseAnxietyFemalemedicine.symptomPsychologyGenome-Wide Association StudyJournal of psychiatric research
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Coping strategies and postpartum depressive symptoms: A structural equation modelling approach.

2014

AbstractBackgroundVariables such as the mother's personality, social support, coping strategies and stressful events have been described as risk factors for postpartum depression. Structural Equation Modelling (SEM) analysis was used to examine whether neuroticism, perceived social support, perceived life events, and coping strategies are associated with postpartum depressive symptoms at the 8th and 32nd weeks.MethodsA total of 1626 pregnant women participated in a longitudinal study. Different evaluations were performed 8 and 32 weeks after delivery. Several measures were used: the Edinburgh Postnatal Depression Scale (EPDS), the Diagnostic Interview for Genetic Studies (DIGS), the Eysenck…

Postpartum depressionAdultCoping (psychology)Longitudinal studymedia_common.quotation_subjectStatistics as TopicPsychological TechniquesPersonality AssessmentDepression PostpartumLife Change EventsSocial supportPredictive Value of TestsPregnancyRisk FactorsAdaptation PsychologicalmedicinePersonalityHumansLongitudinal Studiesmedia_commonNeuroticismPostpartum PeriodSocial Supportmedicine.diseasePrognosisNeuroticismAnxiety DisordersEysenck Personality QuestionnairePsychiatry and Mental healthEdinburgh Postnatal Depression ScaleFemalePsychologyStress PsychologicalClinical psychologyEuropean psychiatry : the journal of the Association of European Psychiatrists
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