0000000000086372

AUTHOR

Massimo Iacoviello

0000-0001-9613-5062

showing 2 related works from this author

ANMCO/ELAS/SIBioC Consensus Document: Biomarkers in heart failure

2017

Abstract Biomarkers have dramatically impacted the way heart failure (HF) patients are evaluated and managed. A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological or pathogenic processes, or pharmacological responses to a therapeutic intervention. Natriuretic peptides [B-type natriuretic peptide (BNP) and N-terminal proBNP] are the gold standard biomarkers in determining the diagnosis and prognosis of HF, and a natriuretic peptide-guided HF management looks promising. In the last few years, an array of additional biomarkers has emerged, each reflecting different pathophysiological processes in the development and progression of HF: …

medicine.drug_classFibrosiGalectin 3Heart failure030204 cardiovascular system & hematologyBioinformatics03 medical and health sciences0302 clinical medicineFibrosismedicineNatriuretic peptideNatriuretic peptides030212 general & internal medicineBiomarkers; Fibrosis; Galectin 3; Heart failure; Inflammation; Natriuretic peptides; Troponin; Cardiology and Cardiovascular MedicinePathologicalInflammationbiologybusiness.industryArticlesBiomarkermedicine.diseaseBrain natriuretic peptideFibrosisTroponinTroponinGalectin-3Heart failurebiology.proteinBiomarker (medicine)businessCardiology and Cardiovascular MedicineBiomarkers; Fibrosis; Galectin 3; Heart failure; Inflammation; Natriuretic peptides; TroponinBiomarkersNatriuretic peptide
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The glucocorticoid in acute decompensated heart failure: Dr Jekyll or Mr Hyde?

2012

Glucocorticoid administration is not recommended in patients with heart failure because of its related sodium and fluid retention. However, previous experimental and clinical studies have demonstrated that glucocorticoids can also induce a diuretic effect and improve renal function in patients with acute decompensated heart failure (ADHF) with refractory diuretic resistance. We report the case of a 65-year-old man with a known diagnosis of aortic stenosis, systolic ventricular dysfunction, and chronic obstructive pulmonary disease who was admitted for ADHF. After 3 days, during which resistance to conventional therapy was observed, intravenous methylprednisolone (60 mg/d) was added to ongoi…

Malemedicine.medical_specialtyAcute decompensated heart failuremedicine.medical_treatmentRenal functionMethylprednisoloneRefractoryInternal medicinemedicineHumansDiureticsGlucocorticoidsAgedHeart Failurebusiness.industryGeneral Medicinemedicine.diseaseBrain natriuretic peptideStenosisglucocorticoid. acute decompensated hert failureEndocrinologyHeart failureAcute DiseaseEmergency MedicineCardiologyDiureticbusinessGlucocorticoidmedicine.drug
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