0000000000087310

AUTHOR

Z. Varga

HΛ3 and H‾Λ¯3 production in Pb–Pb collisions at sNN=2.76 TeV

Abstract The production of the hypertriton nuclei H Λ 3 and H ‾ Λ ¯ 3 has been measured for the first time in Pb–Pb collisions at s NN = 2.76  TeV with the ALICE experiment at LHC. The p T -integrated H Λ 3 yield in one unity of rapidity, d N / d y × B . R . ( H Λ 3 → He 3 , π − ) = ( 3.86 ± 0.77 ( stat. ) ± 0.68 ( syst. ) ) × 10 − 5 in the 0–10% most central collisions, is consistent with the predictions from a statistical thermal model using the same temperature as for the light hadrons. The coalescence parameter B 3 shows a dependence on the transverse momentum, similar to the B 2 of deuterons and the B 3 of 3He nuclei. The ratio of yields S 3 = H Λ 3 / ( He 3 × Λ / p ) was measured to b…

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Nuclear Forensics: A methodology applicable to Nuclear Security and to Non-Proliferation

Nuclear Security aims at the prevention and detection of and response to, theft, sabotage, unauthorized access, illegal transfer or other malicious acts involving nuclear material". Nuclear Forensics is a key element of nuclear security. Nuclear Forensics is defined as a methodology that aims at re-establishing the history of nuclear material of unknown origin. It is based on indicators that arise from known relationships between material characteristics and process history. Thus, nuclear forensics analysis includes the characterization of the material and correlation with production history. To this end, we can make use of parameters such as the isotopic composition of the nuclear material…

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First measurement of the |t|-dependence of coherent J/ψ photonuclear production

The first measurement of the dependence on $|t|$, the square of the momentum transferred between the incoming and outgoing target nucleus, of coherent J/ψ photoproduction is presented. The data were measured with the ALICE detector in ultra-peripheral Pb-Pb collisions at a centre-of-mass energy per nucleon pair $\sqrt{s_{\rm NN}} = 5.02$ TeV with the J/$\psi$ produced in the central rapidity region $|y| < 0.8$, which corresponds to the small Bjorken-$x$ range $(0.3 − 1.4) \times 10 ^{−3}$. The measured $|t|$-dependence is not described by computations based only on the Pb nuclear form factor, while the photonuclear cross section is better reproduced by models including shadowing according t…

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Search for a common baryon source in high-multiplicity pp collisions at the LHC

Physics letters / B B811, 135849 (2020). doi:10.1016/j.physletb.2020.135849

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A phase II trial of chimeric monoclonal antibody G250 for advanced renal cell carcinoma patients.

Contains fulltext : 57114.pdf (Publisher’s version ) (Closed access) Chimeric monoclonal antibody G250 (WX-G250) binds to a cell surface antigen found on >90% of renal cell carcinoma (RCC). A multicentre phase II study was performed to evaluate the safety and efficacy of WX-G250 in metastatic RCC (mRCC) patients. In all, 36 patients with mRCC were included. WX-G250 was given weekly by intravenous infusion for 12 weeks. Patients with stable disease (SD) or response were eligible to receive additional treatment for 8 weeks. None of the 36 enrolled patients experienced any drug-related grade III or IV toxicity. Only three patients had grade II toxicity possibly related to the study medication.…

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Dielectron production in proton-proton and proton-lead collisions at √sNN=5.02TeV

The first measurements of dielectron production at midrapidity (|ηe| &lt; 0.8) in proton–proton and proton–lead collisions at √sNN = 5.02 TeV at the LHC are presented. The dielectron cross section is measured with the ALICE detector as a function of the invariant mass mee and the pair transverse momentum pT, ee in the ranges mee &lt; 3.5 GeV/c2 and pT, ee &lt; 8 GeV/c, in both collision systems. In proton–proton collisions, the charm and beauty cross sections are determined at midrapidity from a fit to the data with two different event generators. This complements the existing dielectron measurements performed at √s = 7 and 13 TeV. The slope of the √s dependence of the three measurements is…

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Cardioprotection by gene therapy: A review paper on behalf of the Working Group on Drug Cardiotoxicity and Cardioprotection of the Italian Society of Cardiology

Ischemic heart disease remains the leading cause of death worldwide. Ischemic pre-, post-, and remote conditionings trigger endogenous cardioprotection that renders the heart resistant to ischemic-reperfusion injury (IRI). Mimicking endogenous cardioprotection by modulating genes involved in cardioprotective signal transduction provides an opportunity to reproduce endogenous cardioprotection with better possibilities of translation into the clinical setting. Genes and signaling pathways by which conditioning maneuvers exert their effects on the heart are partially understood. This is due to the targeted approach that allowed identifying one or a few genes associated with IRI and cardioprote…

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Measurements of mixed harmonic cumulants in Pb–Pb collisions at sNN=5.02 TeV

Correlations between moments of different flow coefficients are measured in Pb–Pb collisions at sNN=5.02 TeV recorded with the ALICE detector. These new measurements are based on multiparticle mixed harmonic cumulants calculated using charged particles in the pseudorapidity region |η|&lt;0.8 with the transverse momentum range 0.2&lt;pT&lt;5.0 GeV/c. The centrality dependence of correlations between two flow coefficients as well as the correlations between three flow coefficients, both in terms of their second moments, are shown. In addition, a collection of mixed harmonic cumulants involving higher moments of v2 and v3 is measured for the first time, where the characteristic signature of ne…

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