Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants

Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean dia…

Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia…

Author response: Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio : a pooled analysis of 458 population-based studies in Asian and Western countries

Artículo con numerosos autores. Sólo quedan reflejados el primero, los pertenecientes a la UAM y el colectivo

Applying Numerical Weather Prediction Models to the Production of New European Wind Atlas : Sensitivity studies of the wind climate to the planetary boundary layer parametrization

Reliable and precise information about the wind speed climate is crucial for the development of wind energy. Meteorological processes in the mesoscale (2 – 200 km) can be represented using Numerical Weather Prediction (NWP) models such as the Weather Research and Forecast model (WRF), but before their application for creating wind energy atlases, their results and sensitivity to modelling parameters should be investigated. Here the WRF model wind speed results for the year 2015 for the Baltic Sea region are investigated, and the effect of the planetary boundary layer parametrization scheme is analyzed.

Repositioning of the global epicentre of non-optimal cholesterol

Publisher's version (útgefin grein)

Riociguat treatment in patients with pulmonary arterial hypertension: Final safety data from the EXPERT registry

OBJECTIVE: The soluble guanylate cyclase stimulator riociguat is approved for the treatment of adult patients with pulmonary arterial hypertension (PAH) and inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension following Phase 3 randomized trials. The EXPosurE Registry RiociguaT in patients with pulmonary hypertension (EXPERT) study was designed to monitor the long-term safety of riociguat in clinical practice. METHODS: EXPERT was an international, multicenter, prospective, uncontrolled, non-interventional cohort study of patients treated with riociguat. Patients were followed for at least 1 year and up to 4 years from enrollment or until 30 days after stopping ri…

New European Wind Atlas: Mesoscale Atlas

The mesoscale part of the New European Wind Atlas (NEWA) was created from WRF model simulations for all of Europe at a grid spacing of 3 km x 3 km, initially covering the 30 years from 1989 to 2018. The WRF model simulations (using WRF V3.8.1) were done in 10 partly overlapping domains using ERA5 reanalysis and OSTIA sea surface temperatures. We used many ensemble members to determine the most suitable configuration for the final production run. The model configuration, production and evaluation of the results against observations are described in Hahmann et al. (2020) and Dörenkämper et al. (2020).Data are accessible through doWIND, an instance of daTap (RESTfull API for data aggregation a…