0000000000093309

AUTHOR

Egle Milia

showing 9 related works from this author

In vivo morphological and clinical effects of a desensitizing agent

2010

Objectives: This study evaluated the in vivo effectiveness of Universal Dentin Sealant (UDS), a new resin-based material, as dentinal desensitizing agent on dentin morphology and clinical symptoms. Materials and methods: Thirty premolars, exhibiting non-carious cervical lesions, and scheduled for extraction for periodontal reasons, were selected for the ultrastructural study. These samples were randomly divided into three groups ( n = 10): group 1, brushing with UDS; group 2, brushing with Flor-Opal ® Varnish (FOV); and group 3, untreated control. After 7 days, teeth were extracted and samples processed for SEM and TEM comparative observations. The in vivo study was carried out on 90 teeth …

Materials sciencebusiness.industryDentistryCold airstomatognathic diseasesin vivo desensitizing agentmedicine.anatomical_structurestomatognathic systemMechanics of MaterialsUntreated controlIn vivoSettore MED/28 - Malattie OdontostomatologicheAssessment methodsOcclusionDentinmedicineGeneral Materials SciencePorous layerbusinessGeneral DentistryUniversal dentin sealant
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Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage

2015

Background: The irradiation of head and neck cancer (HNC) often causes damage to the salivary glands. The resulting salivary gland hypofunction and xerostomia seriously reduce the patient’s quality of life. Purpose: To analyze the literature of actual management strategies for radiation-induced hypofunction and xerostomia in HNC patients. Methods: MEDLINE/PubMed and the Cochrane Library databases were electronically evaluated for articles published from January 1, 1970, to June 30, 2013. Two reviewers independently screened and included papers according to the predefined selection criteria. Results: Sixty-one articles met the inclusion criteria. The systematic review of the literature sugge…

medicine.medical_specialtyPathologymedicine.medical_treatmentMEDLINEReviewCochrane LibraryOral hygieneQuality of lifeSettore MED/28 - Malattie Odontostomatologichemedicinemanagement strategiesPharmacology (medical)General Pharmacology Toxicology and PharmaceuticsMED/42 Igiene generale e applicataIntensive care medicineMED/28 Malattie odontostomatologicheradiation-induced xerostomiaChemical Health and SafetySalivary glandbusiness.industryHead and neck cancerGeneral Medicinemedicine.diseasePathophysiologyRadiation therapymedicine.anatomical_structuresalivary gland hypofunctionradiation-induced xerostomia salivary gland hypofunction management strategiesbusinessSafety Research
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Evaluation of the enamel etching pattern of self-etching adhesives

2010

Objectives: To evaluate the capacity of seven self-etching adhesives (SEAs) to demineralize ground enamel in comparison with traditional phosphoric acid etchant (PAE) using SEM and statistical analysis. Materials and methods: 80 caries-free extracted human third molars were divided into 8 groups ( n = 10). Enamel bur-cut surfaces were prepared and, strictly following the manufacturers’ instructions, treated with three priming agents of two-step self-etching adhesives: Aqua Resulcin Prime (Group 1); Peak™ (Group 2); Clearfil Protect Bond (Group 3); four one-step self-etch (all-in-one) adhesives, G-Bond (Group 4); Artegral One (Group 5); Clearfil S3 Bond (Group 6); Adper Easy Bond (Group 7); …

MolarMaterials scienceEnamel paintbusiness.industryDentistryDemineralizationchemistry.chemical_compoundstomatognathic systemchemistryMechanics of MaterialsGroup (periodic table)Etching (microfabrication)visual_artvisual_art.visual_art_mediumGeneral Materials ScienceAdhesivebusinessGeneral DentistryPhosphoric acidNuclear chemistrySelf etching adhesiveDental Materials
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Short-term response of three resin-based materials as desensitizing agents under oral environmental exposure

2012

Objective. This paper focuses on clinical responses after 7 days of oral exposure to two resin-based materials as desensitizing agents compared to a fluoride varnish and on morphological and analytical study as a means to elucidate the mechanism of action. Materials and methods. The elemental composition of Vertise™ Flow (VF), Universal Dentine Sealant (UDS) and Flor-Opal® Varnish (FOV) were investigated by using an X-ray energy dispersive spectrometer (EDX) in conjunction with a scanning electron microscope (SEM). SEM morphology of the material-treated dentine surfaces and pain reduction ability according to the Visual Analogue Scale (VAS) were evaluated in selected hypersensitive teeth. P…

MaleMaterials scienceScanning electron microscopeVisual analogue scaleResin Materials Desensitizing agentsVarnishAdministration OralDentistryChloridechemistry.chemical_compoundSettore MED/28 - Malattie OdontostomatologichemedicineHumansGeneral Dentistrybusiness.industrySealantFluoride varnishSpectrometry X-Ray EmissionEnvironmental ExposureGeneral MedicineEnvironmental exposureResins Syntheticstomatognathic diseaseschemistryvisual_artMicroscopy Electron Scanningvisual_art.visual_art_mediumFemalebusinessFluoridemedicine.drugBiomedical engineering
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Phenolic Compounds in Extra Virgin Olive Oil Stimulate Human Osteoblastic Cell Proliferation.

2016

In this study, we aimed to clarify the effects of phenolic compounds and extracts from different extra virgin olive oil (EVOO) varieties obtained from fruits of different ripening stages on osteoblast cells (MG-63) proliferation. Cell proliferation was increased by hydroxytyrosol, luteolin, apigenin, p-coumaric, caffeic, and ferulic acids by approximately 11-16%, as compared with controls that were treated with one vehicle alone, while (+)-pinoresinol, oleuropein, sinapic, vanillic acid and derivative (vanillin) did not affect cell proliferation. All phenolic extracts stimulated MG-63 cell growth, and they induced higher cell proliferation rates than individual compounds. The most effective…

0301 basic medicineTime Factorslcsh:MedicineBiochemistryMass SpectrometryTreeschemistry.chemical_compoundAnimal CellsPlant ProductsMedicine and Health SciencesCaffeic acidApigeninlcsh:ScienceLuteolinChromatography High Pressure LiquidConnective Tissue CellsCultured Tumor CellsPrincipal Component AnalysisMultidisciplinaryAgricultureCell DifferentiationRipeningPlantsPhenylethyl AlcoholLipidsOsteoblast DifferentiationChemistryBiochemistryCell ProcessesConnective TissuePhysical SciencesApigeninBiological CulturesCellular TypesAnatomyResearch ArticleOlive TreesCoumaric AcidsResearch and Analysis MethodsVegetable Oils03 medical and health sciencesCaffeic AcidsPhenolsOleuropeinCell Line TumorOleaVanillic acidHumansPhenolsOlive OilCell ProliferationAnalysis of Variance030109 nutrition & dieteticsOsteoblastsDose-Response Relationship Druglcsh:RChemical CompoundsOrganismsBiology and Life SciencesCell BiologyCell CulturesOsteosarcoma CellsAgronomyOlive treesBiological Tissue030104 developmental biologychemistryFruitHydroxytyrosollcsh:QOilsCrop ScienceDevelopmental Biology
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Thymus essential oil extraction, characterization and incorporation in phospholipid vesicles for the antioxidant/antibacterial treatment of oral cavi…

2018

The aim of the work was to extract, characterize, and formulate Thymus capitatus (Tymbra capitata) essential oil in phospholipid vesicles: liposomes, glycerosomes and Penetration Enhancer-containing Vesicles (PEVs). The steam-distilled essential oil was mainly composed of carvacrol. The oil was mixed with lecithin and water to produce liposomes, or different ratios of water/glycerol or water/propylene glycol (PG) to produce glycerosomes and PG-PEVs, respectively. Cryo-TEM showed the formation of unilamellar, spherical vesicles, and light scattering disclosed that their size increased in the presence of glycerol or PG, which improved long-term stability. The formulations were highly biocompa…

Keratinocytes0301 basic medicinefood.ingredientOral cavity bacteriaCell SurvivalSurface Properties030106 microbiologyMicrobial Sensitivity Tests02 engineering and technologyLecithinAntioxidantslaw.inventionThymus PlantGlycols03 medical and health scienceschemistry.chemical_compoundColloid and Surface ChemistryfoodlawOils VolatilePhospholipid vesiclesGlycerolHumansParticle SizePhysical and Theoretical ChemistryPhospholipidsEssential oilLiposomebiologyChemistryVesicleStreptococcusThymus essential oilSurfaces and InterfacesGeneral Medicine021001 nanoscience & nanotechnologybiology.organism_classificationStreptococcus mutansAnti-Bacterial AgentsLactobacillusStreptococcus sanguinisBiochemistryOral mucosaMouth Diseases0210 nano-technologyAntibacterial activityBiotechnologyColloids and Surfaces B: Biointerfaces
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Increases of intracanal and root surface temperatures during the obturation of canal using the E&Q master system and the system

2010

Objectives: The purpose of our study is to assess the increases of intracanal and root surface temperatures during the obturation of canal system using the E&Q Master System and the System B. Materials and methods: A split-tooth model was built. To measure the temperature, 6 grooves for the placement of thermocouples were made in the buccal half of the model. On the mesial side, three grooves were made at 2, 4 and 6 mm from the anatomical apex and were extended to the root surface, while on the distal side three grooves were made at 2, 4 and 6 mm up to the intracanal portion. In each of these grooves was inserted a type T thermocouple (Copper-Costantana) with a diameter of 0.076 mm. 40 cana…

Obturation techniqueRoot surfaceMaterials scienceMaster systemIatrogenic injurybusiness.industryDentistryCanal systemMechanics of MaterialsThermocoupleGeneral Materials ScienceComposite materialbusinessGeneral DentistryDental Materials
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Current dental adhesives systems. A narrative review.

2012

Adhesive dentistry is based on the development of materials which establish an effective bond with the tooth tissues. In this context, adhesive systems have attracted considerable research interest in recent years. Successful adhesive bonding depends on the chemistry of the adhesive, on appropriate clinical handling of the material as well as on the knowledge of the morphological changes caused on dental tissue by different bonding procedures. This paper outlines the status of contemporary adhesive systems, with particular emphasis on chemical characteristics and mode of interaction of the adhesives with enamel and dentinal tissues. Dental adhesives are used for several clinical application…

Adhesive bondingPolyurethanesAcrylic ResinsDentistryDental CementsComposite ResinsComposite resinstomatognathic systemSettore MED/28 - Malattie OdontostomatologicheDrug DiscoveryAdhesive systemHumansDental EtchingDental EnamelPharmacologyOrthodonticsEnamel paintbusiness.industryDentineDental BondingDental Adhesivesstomatognathic diseasesEnamelvisual_artDentin-Bonding AgentsDental EtchingDentinvisual_art.visual_art_mediumNarrative reviewAdhesivebusinessDental adhesivePhosphoric acidCurrent pharmaceutical design
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Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage

2015

Roberto Pinna,1 Guglielmo Campus,2 Enzo Cumbo,3 Ida Mura,1 Egle Milia2 1Department of Biomedical Science, 2Department of Surgery, Microsurgery and Medicine, University of Sassari, Sassari, 3Department of Dental Science, University of Palermo, Palermo, Italy Background: The irradiation of head and neck cancer (HNC) often causes damage to the salivary glands. The resulting salivary gland hypofunction and xerostomia seriously reduce the patient’s quality of life. Purpose: To analyze the literature of actual management strategies for radiation-induced hypofunction and xerostomia in HNC patients. Methods: MEDLINE/PubMed and the Cochrane Library databases were electronically evaluated f…

Therapeutics and Clinical Risk ManagementTherapeutics and Clinical Risk Management
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