0000000000093374

AUTHOR

Anna Viitasalo

showing 14 related works from this author

Cross-sectional associations between cardiorespiratory fitness and NMR-derived metabolic biomarkers in children : the PANIC study

2022

Objective: Cardiorespiratory fitness has been inversely associated with cardiovascular risk across the lifespan. Some studies in adults suggest that higher cardiorespiratory fitness is associated with cardioprotective metabolite profile, but the evidence in children is lacking. Therefore, we investigated the cross-sectional association of cardiorespiratory fitness with serum nuclear magnetic resonance derived metabolic biomarkers in children. Methods: A population sample of 450 children aged 6–8 years was examined. Cardiorespiratory fitness was assessed by a maximal exercise test on a cycle ergometer and quantified as maximal power output normalised for lean body mass assessed by dual-energ…

fyysinen kuntoseerumisydän- ja verisuonitauditlapset (ikäryhmät)biomarkkeritaineenvaihduntatuotteetriskitekijätkliininen rasituskoe
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Longitudinal associations of physical activity and sedentary time with cardiometabolic risk factors in children

2018

BACKGROUND There are few prospective studies on the associations of changes in objectively measured vigorous physical activity (VPA∆ ), moderate-to-vigorous physical activity (MVPA∆ ), light physical activity (LPA∆ ), and sedentary time (ST∆ ) with changes in cardiometabolic risk factors (∆ ) in children. We therefore investigated these relationships among children. METHODS The participants were a population sample of 258 children aged 6-8 years followed for 2 years. We assessed PA and ST by a combined heart rate and movement sensor; computed continuous age- and sex-adjusted z-scores for waist circumference, blood pressure, and fasting insulin, glucose, triglycerides, and high-density lipop…

Blood GlucoseMaleCross-sectional studyphysical activityBlood Pressureliikunta030204 cardiovascular system & hematologyBody fat percentagechemistry.chemical_compound0302 clinical medicineHeart RateRisk FactorsInsulinOrthopedics and Sports MedicineLongitudinal StudiesProspective StudiesChildta315Prospective cohort studyFinlandAnthropometryriskitekijätLipidsCardiovascular DiseasesFemalelipids (amino acids peptides and proteins)Waist Circumferencefyysinen aktiivisuusmedicine.medical_specialtyWaistPhysical Therapy Sports Therapy and Rehabilitationpitkittäistutkimusta3111Article03 medical and health sciencesMetabolic DiseaseschildrenInternal medicineHeart ratemedicineHumansExerciselapsetCholesterolbusiness.industryterveydentila030229 sport sciencesAnthropometrycardiometabolic risk factorsCross-Sectional StudiesBlood pressurechemistrySedentary BehaviorbusinessScandinavian Journal of Medicine & Science in Sports
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A 2 year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children: the PANIC stud…

2020

Abstract Aims/hypothesis We studied for the first time the long-term effects of a combined physical activity and dietary intervention on insulin resistance and fasting plasma glucose in a general population of predominantly normal-weight children. Methods We carried out a 2 year non-randomised controlled trial in a population sample of 504 children aged 6–9 years at baseline. The children were allocated to a combined physical activity and dietary intervention group (306 children at baseline, 261 children at 2-year follow-up) or a control group (198 children, 177 children) without blinding. We measured fasting insulin and fasting glucose, calculated HOMA-IR, assessed physical activity and se…

Blood GlucoseMaleEndocrinology Diabetes and Metabolismmedicine.medical_treatmentPhysiologyphysical activitylean body massruokavaliotBody fat percentageHOMA-IRlaw.inventionBody Mass Indexglukoosi0302 clinical medicineRandomized controlled triallawInsulinBody Size030212 general & internal medicineglucoseChildChildreninterventioneducation.field_of_studyBody movementinterventiotutkimusFastingSedentary timebody fatLean body massBody fatBody CompositionFemalefyysinen aktiivisuusinsulinPopulationsedentary time030209 endocrinology & metabolismlapset (ikäryhmät)InterventioninsuliiniArticle03 medical and health sciencesInsulin resistancechildrenHeart rateInternal MedicinemedicineHumanseducationExercisekehonkoostumusbusiness.industryPhysical activityInsulinmedicine.diseaseDietGlucoseLean body massInsulin Resistancebusinessdiet
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The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study

2020

Funder: Opetus- ja Kulttuuriministeriö; doi: http://dx.doi.org/10.13039/501100003126

Very low-density lipoproteinphysical activityMedicine (miscellaneous)030204 cardiovascular system & hematologyruokavaliot0302 clinical medicine030212 general & internal medicineChildChildreninterventioneducation.field_of_studyNutrition and DieteticsinterventiotutkimusOriginal ContributionLDL cholesterolmedicine.symptomfyysinen aktiivisuuselintavatmedicine.medical_specialtylipoproteiinitLipoproteinsPopulationPhysical activitylapset (ikäryhmät)Intervention03 medical and health scienceschildrenInternal medicineIntervention (counseling)Heart ratePlasma lipidsmedicineHumansLDL-kolesterolieducationExerciseTriglyceridesLdl cholesterolPhysical activitybusiness.industryCholesterol HDLPanicCholesterol LDLDietary FatsDietlipoproteinsEndocrinologysense organsSedentary BehaviordietbusinessEuropean Journal of Nutrition
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The effects of a 2-year individualized and family-based lifestyle intervention on physical activity, sedentary behavior and diet in children

2016

To investigate the effects of a long-term, individualized and family-based lifestyle intervention on physical activity, sedentary behavior and diet quality in children.We carried out a 2-year intervention study in a population sample of 506 children aged 6-8years in Finland in 2007-2012. We allocated the participants at baseline in the intervention and control group. We assessed physical activity and sedentary behavior by questionnaires and diet by food records.Total physical activity (+9min/d in intervention group vs. -5min/d in control group, p=0.001 for time*group interaction), unsupervised physical activity (+7min/d vs. -9min/d, p0.001) and organized sports (+8min/d vs. +3min/d, p=0.001…

MaleTotal physical activityGerontologymedicine.medical_specialtyEpidemiologyHealth BehaviorPhysical activityphysical activityHealth Promotionta311103 medical and health sciences0302 clinical medicinechildrenSurveys and Questionnairessedentary behavior030225 pediatricsIntervention (counseling)Lifestyle interventionGroup interactionHumansMedicineFamily030212 general & internal medicineChildta315ExerciseFinlandinterventionbusiness.industryPublic Health Environmental and Occupational HealthPanicta3141Sedentary behaviorPhysical therapyFemalemedicine.symptomdietbusinessFamily basedPreventive Medicine
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The effects of an 8-year individualised lifestyle intervention on food consumption and nutrient intake from childhood to adolescence: the PANIC Study.

2021

Abstract We aimed to investigate the effects of a long-term, individualised, family-based lifestyle intervention on food consumption and nutrient intake from childhood to adolescence. We conducted an 8-year diet and physical activity intervention study in a population sample of children aged 7–9 years at baseline in 2007–2009. We allocated the participants to the intervention group (n 306) and the control group (n 198). We assessed diet by 4-d food records at baseline, 2-year follow-up and 8-year follow-up. We analysed the data using linear mixed-effects models adjusted for age at baseline and sex. The consumption of vegetables and vegetable oil-based spreads (fat ≥60 %) increased in the in…

elintavatNutrition and Dieteticsnutrient intakeAdolescentEndocrinology Diabetes and Metabolismlapset (ikäryhmät)DietruokatottumuksetEatingchildrennuoretfood consumptionVegetablesHumansravintoaineetadolescentsChildEnergy IntakeravitsemusLife StyleinterventioninterventioFood SciencePANIC StudyJournal of nutritional science
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Associations of Cardiorespiratory Fitness and Adiposity With Arterial Stiffness and Arterial Dilatation Capacity in Response to a Bout of Exercise in…

2019

Purpose: To investigate the associations of directly measured peak oxygen uptake (V˙O2peak) and body fat percentage (BF%) with arterial stiffness and arterial dilatation capacity in children. Methods: Findings are based on 329 children (177 boys and 152 girls) aged 8–11 years. V˙O2peak was assessed by a maximal cardiopulmonary exercise test on a cycle ergometer and scaled by lean body mass (LM). BF% and LM were measured by bioelectrical impedance. Stiffness index (measure of arterial stiffness) and change in reflection index (ΔRI, measure of arterial dilatation capacity) were assessed by pulse contour analysis. Data were analyzed by linear regression models. Results: VO2peak/LM was positive…

aerobic fitnessfyysinen kuntomaximal exercise testendothelial functionlastentautioppilapset (ikäryhmät)kehonkoostumusharjoitusvaste
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Associations of Cardiorespiratory Fitness and Adiposity With Arterial Stiffness and Arterial Dilatation Capacity in Response to a Bout of Exercise in…

2019

Purpose: To investigate the associations of directly measured peak oxygen uptake (V˙O2peak) and body fat percentage (BF%) with arterial stiffness and arterial dilatation capacity in children. Metho...

Malemedicine.medical_specialty030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationBody fat percentage03 medical and health sciences0302 clinical medicineOxygen ConsumptionVascular StiffnessInternal medicinemedicineAerobic exerciseHumansOrthopedics and Sports MedicineChildExerciseAdipositybusiness.industryVO2 maxCardiorespiratory fitness030229 sport sciencesArteriesmedicine.diseaseCross-Sectional StudiesCardiorespiratory FitnessPediatrics Perinatology and Child HealthArterial stiffnessCardiologyExercise TestLinear ModelsFemaleMaximal exercisebusinessPediatric exercise science
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Peak oxygen uptake cut-points to identify children at increased cardiometabolic risk - The PANIC Study.

2019

We aimed to develop cut -points for directly measured peak oxygen uptake (VO2peak ) to identify boys and girls at increased cardiometabolic risk using different scaling methods to control for body size and composition. Altogether 352 children (186 boys, 166 girls) aged 9 – 11 years were included in the analyses. We measured VO2peak directly during a maximal cycle ergometer exercise test and lean body mass (LM) by bioelectrical impedance. We computed a sex - and age -specific cardiometabolic risk score (CRS) by summing important cardiometabolic risk factors and defined increased cardiometabolic risk as >1 standard deviation above the mean of CRS. Receiver operating characteristics curves wer…

maximal exerciseMalemedicine.medical_specialtyPhysical TherapyPhysical Therapy Sports Therapy and RehabilitationSports Therapy and Rehabilitation030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineOxygen ConsumptionchildrenPredictive Value of TestsRisk FactorsInternal medicinemedicinemaksimaalinen hapenottoJournal ArticleHumansOrthopedics and Sports Medicineta315ChildaineenvaihduntalapsetCardiovascular Diseases/diagnosiskehonkoostumusaerobic fitnessadipositymetabolic healthbusiness.industryArea under the curveVO2 maxCardiorespiratory fitness030229 sport sciencesta3142riskitekijätConfidence intervalfyysinen kuntoCardiorespiratory FitnessROC CurveCardiovascular DiseasesLean body massCardiologyExercise TestFemaleRisk assessmentbusinessBody mass indexBioelectrical impedance analysisallometric scalingScandinavian journal of medicinescience in sports
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Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults?

2022

Objectives Cardiorespiratory fitness (CRF) has been inversely associated with risk of cardiometabolic diseases. However, there are no studies comparing the independent associations of CRF scaled by body size and composition using different approaches with cardiometabolic risk factors between children and adults. We therefore investigated these associations in children and adults using same measures for CRF and cardiometabolic risk factors. Design Cross-sectional. Methods A total of 352 children (47.2 % girls) and 572 men were included in the study. Peak oxygen uptake (V̇O2peak) was measured during a maximal exercise test on a cycle ergometer and was scaled by total body mass (BM−1), total f…

MaleAdultobesitykolesterolilastentautioppiBlood Pressurelapset (ikäryhmät)Physical Therapy Sports Therapy and RehabilitationHDL-kolesterolimetabolic syndromepaediatricsaineenvaihduntahäiriötRisk Factorsinsulin resistanceterveysvaikutuksetHumansInsulinOrthopedics and Sports MedicineLDL-kolesteroliChildmetabolinen oireyhtymäTriglyceridesaikuisetkuntokehonkoostumusMetabolic Syndromebody compositionCholesterol HDLylipainoriskitekijätinsuliiniresistenssifitnessmittausmenetelmätCross-Sectional StudiesCardiorespiratory FitnessCardiovascular DiseasesPhysical FitnesslihavuusFemaleennaltaehkäisyInsulin ResistanceJournal of Science and Medicine in Sport
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Longitudinal Associations of Fitness, Motor Competence, and Adiposity with Cognition

2019

Purpose: The purpose of this study was to investigate the longitudinal associations of cardiorespiratory fitness (CRF), motor competence (MC), and body fat percentage (BF%) with cognition in children. Methods: Altogether, 371 children (188 boys and 183 girls) 6–9 yr of age at baseline participated in this 2-yr follow-up study. We assessed CRF by maximal cycle ergometer test, computed the MC score from the z-scores of the 50-m shuttle run, static balance, and box and block test results, measured BF% by dual-energy x-ray absorptiometry, and assessed cognition using the Raven’s Coloured Progressive Matrices (RCPM) score. The associations were studied by linear regression analysis and repeated-…

Maleobesitycognitive functionsCHILDRENBody fat percentageCognition0302 clinical medicinenuoretOrthopedics and Sports MedicineCOGNITIVE FUNCTIONSLongitudinal Studiesta315Childta515FinlandAdiposityyouthylipainoCognitionta3142MOTOR SKILLSfyysinen kuntoCardiorespiratory FitnessYOUTHMotor SkillsOBESITYFemaleCARDIORESPIRATORY FITNESSkognitiiviset taidotMulti-stage fitness testmedicine.medical_specialtyPhysical Therapy Sports Therapy and Rehabilitation03 medical and health sciencesRaven's Progressive MatriceschildrenInternal medicineLinear regressionmedicineHumansmotoriset taidotlapsetbusiness.industryCardiorespiratory fitness030229 sport sciencesmedicine.diseaseObesityConfidence intervallihavuusnuoruusbusinessFollow-Up Studies
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The Effects of a 2-year Individualized and Family-based Lifestyle Intervention on Physical Activity, Sedentary Behavior and Diet in Children

2016

Objective To investigate the effects of a long-term, individualized and family-based lifestyle intervention on physical activity, sedentary behavior and diet quality in children. Methods We carried out a 2-year intervention study in a population sample of 506 children aged 6–8 years in Finland in 2007–2012. We allocated the participants at baseline in the intervention and control group. We assessed physical activity and sedentary behavior by questionnaires and diet by food records. Results Total physical activity (+ 9 min/d in intervention group vs. − 5 min/d in control group, p = 0.001 for time*group interaction), unsupervised physical activity (+ 7 min/d vs. − 9 min/d, p < 0.001) and orga…

childrensedentary behaviorphysical activitydietinterventio
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Plasma polyunsaturated fatty acids are directly associated with cognition in overweight children but not in normal weight children

2016

Aim Polyunsaturated fatty acids are essential nutrients for the normal development of the brain. We investigated the associations between plasma polyunsaturated fatty acids and cognition in normal weight and overweight children. Methods The study recruited 386 normal weight children and 58 overweight children aged six to eight years and blood samples were drawn after a 12-hour fast. We assessed plasma polyunsaturated fatty acids using gas chromatography, cognition using Raven's Coloured Progressive Matrices, and overweight and obesity using the age-specific and sex-specific cut-offs from the International Obesity Task Force. The data were analysed by linear regression analyses adjusted for …

0301 basic medicinecognitionmedicine.medical_specialtyOverweightta311103 medical and health scienceschemistry.chemical_compound0302 clinical medicineRaven's Progressive MatricesInternal medicinemedicineHumansoverweight030212 general & internal medicineChildplasmachemistry.chemical_classification030109 nutrition & dieteticsbusiness.industryta3141fish consumptionGeneral Medicinemedicine.diseaseEicosapentaenoic acidObesityEndocrinologychemistryDocosahexaenoic acidCase-Control StudiesPediatrics Perinatology and Child HealthFatty Acids UnsaturatedArachidonic acidmedicine.symptomEssential nutrientbusinessPolyunsaturated fatty acidpolyunsaturated fatty acidsActa Paediatrica
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Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in child…

2016

Background: Evidence on the effects of lifestyle interventions on plasma fatty acid composition in children is limited. Objective: We investigated the effects of a dietary and physical activity intervention on plasma fatty acid composition of cholesteryl esters (CEs) and phospholipids and estimated desaturase and elongase activities in children. Design: We conducted a 2-y controlled dietary and physical activity intervention based on Finnish nutrition and physical activity recommendations in a population sample of 506 children aged 6–8 y. We assessed plasma fatty acid composition by gas chromatography and estimated desaturase and elongase activities as the ratio of product fatty acids to pr…

Fatty Acid DesaturasesMaleHealth BehaviorMedicine (miscellaneous)physical activity030204 cardiovascular system & hematologychemistry.chemical_compound0302 clinical medicineFood scienceChildta315FinlandPhospholipidsinterventionchemistry.chemical_classificationNutrition and Dieteticsalpha-Linolenic Acidta3141elongaseLipidsTreatment OutcomeBiochemistrycholesteryl esterFatty Acids UnsaturatedCholesteryl esterFemaleCholesterol EstersStearic acidPolyunsaturated fatty acidFatty Acid ElongasesLinoleic acidPhysical activityPhospholipidGuidelines as Topic030209 endocrinology & metabolismHealth Promotionta3111Linoleic Acid03 medical and health scienceschildrenAcetyltransferasesHumansExerciseLife StylephospholipidFatty acidOleic acidchemistryfatty aciddietdesaturaseAmerican Journal of Clinical Nutrition
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