0000000000094045

AUTHOR

Ligia Juliana Dominguez Rodriguez

LA DOMOTICA A FAVORE DEGLI ANZIANI

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Oral Magnesium Supplementation and Endothelial Function in diabetic and Hypertensive Older Patients

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I LUOGHI DELLA CURA E DEL MORIRE: REPARTO DI GERIATRIA: TRE ANNI DI ATTIVITÀ

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ADHERENCE TO A MEDITERRANEAN DIET AND PHYSICAL FUNCTION DECLINE AMONG OLDER PERSONS

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DEPRESSION, SELF-RATED HEALTH STATUS AND DISABILITY THE EUROPEAN STUDY ON ADULT WELL-BEING (ESAW)

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MAGNESIUM AND THE CARDIOMETABOLIC SYNDROME

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EQUILIBRIO ACIDO-BASE E SQUILIBRI IDROELETTROLITICI NELL’ANZIANO

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MILD COGNITIVE IMPAIRMENT (MCI): LA ZONA GRIGIA

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PREVENZIONE NELLE MALATTIE NEURODEGENERATIVE NELL’ANZIANO

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DEFICIT COGNITIVO E DIABETE MELLITO. STUDIO OSSERVAZIONALE

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POOR DIET, LITTLE EXERCISE, SMOKING: WESTERN WAYS THAT PROMOTE HEART DISEASE

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SUCCESSFUL AGING: QUALITY AND QUANTITY

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222. DEPRESSIONE E M. DI PARKINSON: VALUTAZIONE DEL TONO DELL’UMORE IN 20 PAZIENTI ULTRASETTANTENNI IN TRATTAMENTO CON L-DOPA E/O DOPAMINO-AGONISTI. DATI PRELIMINARI

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ANEMIA E DECLINO FUNZIONALE NELL’ANZIANO

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INDUCTION OF VEGF AND B-FGF RELEASE BY ELECTRO NEUROSTIMULATION (FREMS) IN DIABETIC POLYNEUROPATHY

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MIGLIORAMENTO DEI PARAMETRI FUNZIONALI DEL NERVO SENSITIVO E MOTORIO NEL PAZIENTE CON NEUROPATIA DIABETICA DOLOROSA MEDIANTE UN NUOVO SISTEMA DI NEUROMODULAZIONE AD IMPULSI

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Similar prediction of the decreased total mortality, diabetes incidence or cardiovascular events using a relative- and an absolute-component Mediterranean diet score: the sun COHORT .

Abstract Background and Aim: Accumulated evidence supports the effectiveness of Mediterranean-type diets (MeDiet) in reducing mortality and preventing several chronic diseases. Widely used scores to assess adherence to MeDiet are based on specific sample characteristics; alternatively, they might be built according to absolute/normative cut-off points for the consumption of specific food groups (pre-defined servings/day or/week). The aim of this study was to compare sample-specific MeDiet adherence scores (MDS) versus absolutenormative scores (Mediterranean Diet Adherence Screener e MEDAS) on their association with macronutrient intake, total mortality and incidence of chronic diseases. Des…

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VALUTAZIONE DELLA PERFORMANCE COGNITIVA IN PAZIENTI POST ICTUS

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TYPE 2 DIABETES AND ALZHEIMER’S DISEASE

Epidemiological and biological evidences support a link between type 2 diabetes mellitus (DM2) and Al-zheimer’s disease (AD). Persons with diabetes have a higher incidence of cognitive decline and an increased risk of developing all types of dementia. Cognitive deficits in persons with diabetes mainly affect the ar-eas of psychomotor efficiency, attention, learning and memory, mental flexibility and speed, and executive function. The strong epidemiological association has suggested the existence of a physiopathological link. The determinants of the accelerated cognitive decline in DM2, however, are less clear. Increased cortical and subcortical atrophy have been evidenced after con-trolling…

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LOW-COST CALORIES AND THE EPIDEMIC OF CARDIOVASCULAR DISEASE IN LESS DEVELOPED COUNTRIES

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RIABILITAZIONE NEUROMOTORIA NELLA M. DI PARKINSON: CONDIZIONAMENTO SENSORIALE

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MAGNESIUM METABOLISM IN TYPE 2 DIABETES MELLITUS

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Violenza contro le persone anziane

Abuse against elderly persons is extremely frequent, although very often is not declared, and entails high human and financial costs. There are on the whole three types of abuse including domestic, institutional, and auto inflicted. It is difficult to get enough information to define the real dimension of the problem, but data from the National Elder Abuse Incidence Study (NEAIS) describe an increasing and expanding phenomenon. The large proportions of this type of violence has lead the World Health Organization to propose strategies primarily focused on three points: Awareness, Education en Defence. An important role in the prevention and diagnosis of elderly abuse is in the hands of the p…

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MAGNESIUM METABOLISM IN TYPE 2 DIABETES MELLITUS, METABOLIC SYNDROME AND INSULIN RESISTANCE.

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EFFECTS OF POLYENOIC ω-3 FATTY ACIDS ON OXIDATIVE STRESS IN HYPERTENSIVE ELDERLY SUBJECTS

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STUDIO "EUROFAMCARE": SINTESI DEI PRINCIPALI RISULTATI RELATIVI AL CAMPIONE ITALIANO DI CAREGIVERS

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FUNCTIONAL ASSESSMENT OF OLDER PERSONS: ROLE OF COMPREHENSIVE GERIATRIC ASSESSMENT IN GERIATRIC ONCOLOGY

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QUALITÀ DELLA VITA NELL’ANZIANO

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HYPERTENSION AS A RISK FACTOR OF COGNITIVE IMPAIRMENT AND DEMENTIA IN THE ELDERLY.

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MALATTIA DI PARKINSON: FATTORI AMBIENTALI E GENETICI

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OLIVE OIL CONSUMPTION AND RISK OF CORONARY HEART DISEASE AND/OR STROKE: A META-ANALYSIS OF CASE-CONTROL, COHORT AND INTERVENTION STUDIES

Increasing evidence suggests that the Mediterranean diet can reduce the risk of CVD. Olive oil is the hallmark of this dietary pattern. We conducted a meta-analysis of case–control, prospective cohort studies and a randomised controlled trial investigating the specific association between olive oil consumption and the risk of CHD (101 460 participants) or stroke (38 673 participants). The results of all observational studies were adjusted for total energy intake. The random-effects model assessing CHD as an outcome showed a relative risk (RR) of 0·73 (95% CI 0·44, 1·21) in case–control studies and 0·96 (95% CI 0·78, 1·18) in cohort studies for a 25 g increase in olive oil consumption. In co…

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TORRE DI LONDRA: DEMENZA FRONTO-TEMPORALE E DISTURBO DELL’ UMORE

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MAGNESIUM METABOLISM IN INSULIN RESISTENCE, METABOLIC SYNDROME AND TYPE 2 DIABETES MELLITUS

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HYPERTENSION AS A RISK FACTOR FOR COGNITIVE IMPAIRMENT AND DEMENTIA IN THE ELDERLY

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PSEUDODEMENZA, DEPRESSIONE E DEMENZA

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Per una Educazione alla Salute. In: DOMINGUEZ LJ, BORRUSO V.. PER UNA EDUCAZIONE ALLA SALUTE. TEXTBOOK OF THE COURSE: “HEALTH AND NUTRITION EDUCATION” ORGANIZED BY AUSER, UNIVERSITY OF FREE TIME AND PERMANENT EDUCATION “LEONARDO DA VINCI”

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Effects of polyenoic omega-3 fatty acid on oxidative stress in hypertensive elderly subjects

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Non-healing ulcers: domiciliary assistance including electrical neurostimulation - clinical outcome and cost reduction

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DEPRESSIONE, ANZIANI E PSICOTERAPIA

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VALUTAZIONE DELLE ALTERAZIONI COMPORTAMENTALI IN PAZIENTI CON DEMENZA DI ALZHEIMER

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L’ASSISTENZA DOMICILIARE INTEGRATA (ADI) E LE LESIONI DA PRESSIONE

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L’IPOTIROIDISMO NELLE PERSONE ANZIANE: IMPORTANZA DI UNA ADEGUATA TERAPIA SOSTITUTIVA ORMONALE

La prevalenza dei disturbi della ghiandola tiroidea aumenta con l’età, soprattutto nelle donne. L’ipofunzione tiroidea conclamata in età avanzata può manifestarsi clinicamente con sintomi e segni simili alle modificazioni che normalmente accompagnano l’invecchiamento o come disturbi di altri organi. Per tale motivo, un alto indice di sospetto è essenziale per rilevare l’ipotiroidismo in anziani con comorbilità multiple, alterazioni nutrizionali e/o polifarmacoterapia. La decisione di iniziare una terapia sostitutiva ormonale nell’ipotiroidismo conclamato non è discutibile. Viceversa, esiste ancora controversia sulla decisione di trattare o non trattare l’ipotiroidismo subclinico; le raccoma…

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EFFETTI BENEFICI DELLA DIETA MEDITERRANEA. PIÙ LONGEVI CONSUMANDO OLIO D’OLIVA

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LA DIETA MEDITERRANEA E L’OLIO D’OLIVA: CENT’ANNI DI … SALUTE!

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NECESSITÀ DEL RICOVERO IN RSA IN ALCUNI PAZIENTI CON DEMENZA DI ALZHEIMER. CASO CLINICO

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CORRELAZIONE TRA DEMENZA E DEPRESSIONE. Studio su 60 pazienti ambulatoriali

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Effects of drug therapy on cardiac arrhythmias and ischemia in hypertensives with LVH.

Left ventricular hypertrophy (LVH) in hypertensive subjects is associated with an increased prevalence of ventricular arrhythmias. To evaluate the effect of antihypertensive treatment on cardiac arrhythmias (CA) and transient episodes of myocardial ischemia (TEMI), we studied 46 hypertensive patients with LVH, divided into four groups randomly treated with enalapril, hydrochlorothiazide (HCTZ), atenolol, or verapamil (SR-V) for 6 months. Office blood pressure and office heart rate values were recorded, in basal conditions, after 1 and 6 months of treatment, and all patients underwent echocardiography, electrocardiographic Holter monitoring, and stress testing. All drugs significantly lowere…

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Elevati livelli di omocisteina e ridotta forza muscolare in soggetti anziani

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LA STIMOLAZIONE ELETTRICA FREMS NEL TRATTAMENTO DELLE LESIONI ULCERATIVE CUTANEE DIFFICILI IN PAZIENTI IN ASSISTENZA DOMICILIARE. DESCRIZIONE DI DUE CASI

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MAGNESIUM INTAKE IN THE PATHOPHYSIOLOGY AND TREATMENT OF THE CARDIOMETABOLIC SYNDROME: WHERE ARE WE IN 2006?

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L’AZITROMICINA NEL TRATTAMENTO DELLA GASTROPARESI DIABETICA NELL’ANZIANO: UN CASO CLINICO

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EFFETTO DEGLI ESTRATTI DI PAPAYA FERMENTATA SULLO STRESS OSSIDATIVO IN PAZIENTI CON MALATTIA DI ALZHEIMER

Brain tissue is particularly susceptible to oxidative damage, which has been associated with pathological findings of Alzheimer's disease (AD), such as amyloid plaques and protein fibrils. Oxidative stress alterations, including increased production of reactive oxygen metabolites, decline of antioxidant systems, and decreased efficiency in repairing molecules, have been linked to the development of AD. Postmortem studies on brain tissue from AD patients have shown several oxidative damage markers, such as increased lipid peroxidation, oxidative damage of proteins, glyco-oxidation, and reduction of antioxidant systems. We studied 40 patients referred to our Geriatric Unit (age 78,2 ± 1,1 yea…

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INTEGRATIVE MEDICINE

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“L’incendio di borgo” - Between heavy and meaningful burdens

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Osteoporosi e diabete mellito. [Osteoporosis and diabetes]

Diabetes mellitus and osteoporosis are chronic diseases with an elevated and growing incidence in the elderly. Recent epidemiological studies have demonstrated an elevated risk of hip, humerus and foot fractures in elder diabetic subjects. While type 1 diabetes is generally associated with a mild reduction in bone mineral density (BMD), type 2 diabetes, more prevalent in old subjects, is frequently linked to a normal or high BMD. Studies on experimental models of diabetes have suggested an altered bone structure that may help to explain the elevated risk of fractures observed in these animals and may as well help to explain the paradox of an incremented risk of fractures in type 2 diabetic …

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DEFICIT COGNITIVO E DIABETE. STUDIO OSSERVAZIONALE

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CHIRURGIA BARIATRICA COME CAUSA DI OSTEOMALACIA / OSTEOPOROSI E DISABILITÀ SEVERE. CASO CLINICO

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Elevated homocysteine is associated with lower handgrip strength in elderly subjects

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MAGNESIUM HOMEOSTASIS AND AGING

aGING IS VERY OFTEN ASSOCIATED WITH MAGNESIUM (mG) DEFICIT.tOTAL PLASMA MAGNESIUM CONCENTRATIONS ARE REMARKABLY CONSTANT IN HEALTHY SUBJECTS THROUGHOUT LIFE

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MILD COGNITIVE IMPAIRMENT: LA ZONA GRIGIA

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TERAPIA DELLA SARCOPENIA

La sarcopenia e la cachessia sono i disordini muscolari più comune negli adulti. La principale differenza tra le due condizioni è che, a livello istologico, la sarcopenia rappresenta una condizione età correlata che si accompagna a neurodegenerazione, mentre la cachessia è una malattia infiammatoria del muscolo, che è associata a perdita di tessuto adiposo e ad anoressia. E’ stato dimostrato che entrambe le condizioni, nonostante le differenze nella etiologia e fisiopatologia, rispondono positivamente a trattamenti che aumentano la massa e la forza muscolare. Il gold standard attuale della terapia della sarcopenia è l'esercizio fisico. Inoltre, esistono una serie di farmaci che sono disponi…

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INTERVENTI SUL CAREGIVER DEL PAZIENTE CON DEMENZA

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Teriparatide (1-34) vs. parathyroid hormone (1-84) in women with severe postmenopausal osteoporosis: a randomized, head-to-head study.

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HYPERTENSION AS A RISK FACTOR OF FRAILTY AND DISABILITY IN THE ELDERLY

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SCONTRI AUTOMOBILISTICI NEI PAZIENTI CON DISTURBI COGNITIVI: QUALI SOLUZIONI?

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MAGNESIUM AND ANABOLIC HORMONES IN OLDER MEN

Optimal nutritional and hormonal statuses are determinants of successful age-ing. The age associated decline in anabolic hormones such as testosterone and insulin-like growth factor 1 (IGF-1) is a strong predictor of metabolic syn-drome, diabetes and mortality in older men. Studies have shown that magne-sium intake affects the secretion of total IGF-1 and increase testosterone bioactivity. This observation suggests that magnesium can be a modulator of the anabolic ⁄ catabolic equilibrium disrupted in the elderly people. However, the relationship between magnesium and anabolic hormones in men has not been investigated. We evaluated 399 ‡65-year-old men of CHIANTI in a study population repres…

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IPERTENSIONE ARTERIOSA E DETERIORAMENTO COGNITIVO

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ATTUALE APPROCCIO TERAPEUTICO NEI PAZIENTI CON MALATTIA DI ALZHEIMER

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DISTURBI DEL SONNO IN SOGGETTI ANZIANI

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Correlazione tra LLC-B e infezione da HCV nell'anziano

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DEPRESSIONE E RISCHIO DI EVENTI CEREBROVASCOLARI ACUTI

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7. INAPPROPRIATE PRESCRIPTION OF ALLOPURINOL AND FEBUXOSTAT AND RISK OF ADVERSE EVENTS IN THE ELDERLY: RESULTS FROM THE REPOSI REGISTRY

Purpose To investigate the prevalence of xanthine oxidase (XO) inhibitors prescription at admission and discharge in elderly hospital in-patients, to analyze the appropriateness of their use in relation to evidence-based indications, to evaluate the predictors of inappropriate prescription at discharge and the association with adverse events 3 months after hospital discharge. Methods This cross-sectional study, based upon a prospective registry, was held in 95 Italian internal medicine and geriatric hospital wards. The sample included 4035 patients aged 65 years or older at admission and 3502 at discharge. The prescription of XO inhibitors was considered appropriate in patients with diagnos…

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IL PAZIENTE ANZIANO CON FRATTURA DI FEMORE: VALUTAZIONE E SUPPORTO NUTRIZIONALE

Osteoporosis in the elderly population is a major health problem worldwide, because it is associated with fragility fractures with consequent financial burden for health systems. Europe and North America are the regions where half of all hip fractures among elderly people occurred today, with Scandinavian countries reporting the highest incidence worldwide. Undernutrition, particularly protein malnutrition, is frequent in elderly with osteoporotic hip fracture, although, the role of dietary protein intake in osteoporosis remains controversial. Poor nutritional status is associated with higher comorbidity indices, mortality and readmissions in patients with femoral fracture. Another crucial …

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Test-and-treat strategy for helicobacter pylori infection in older patients.

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THE ROLE OF CALCIUM AS A METALLOTHERAPEUTIC DRUG

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DIABETE E IPERTENSIONE: IMPORTANZA DEL CONTROLLO PRESSORIO OTTIMALE E DELLE MODIFICAZIONI DELLO STILE DI VITA

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EcocolorDoppler epiaortico e transmuralico nella diagnosi differenziale delle demenze

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QUALITA’ DI VITA NEGLI ANZIANI: POSSIBILI INDICATORI

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LEPTINA E BMI IN SOGGETTI ANZIANI DIABETICI E NON DIABETICI

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PREVENZIONE DELLE MALATTIE NEURODEGENERATIVE NELL’ANZIANO

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LA RIABILITAZIONE PSICOSOCIALE IN PAZIENTI CON DEFICIT COGNITIVO LIEVE O LIEVE-MODERATO: L’ESPERIENZA DELL’ AREA TEMPO LIBERO

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DECLINO COGNITIVO E CADASIL: CASO CLINICO

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SENILE ANOREXIA IN DIFFERENT GERIATRIC SETTINGS IN ITALY

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INCREMENTO DELLA ASPETTATIVA DI VITA IN PAZIENTI CON TALASSEMIA INTERMEDIA: CASO CLINICO

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TEST-AND-TREAT ANCHE PER LA POPOLAZIONE GERIATRICA CON HP-INFEZIONE?

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SEPSI IN SOGGETTI PORTATORI DI ELETTROCATETERE INTRACARDIACO.DESCRIZIONE DI DUE CASI CLINICI

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DEPRESSIONE E DISTURBI COGNITIVI NELL’ANZIANO

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Circulating magnesium levels and disability in elderly hospitalized subjects

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Trattamento delle lesioni ulcerative cutanee difficili: esistono spazi di miglioramento?

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DOMOTICA, UTENZA DEBOLE E ANZIANI

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PSICOTERAPIA CON PAZIENTI GERIATRICI: IL GRUPPO TERAPEUTICO COME STRUMENTO DI CAMBIAMENTO IN QUADRO DI UMORE DEPRESSO

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OXIDATIVE STRESS AND ALZHEIMER’S DISEASE

Introduction: Brain tissue is particularly susceptible to oxidative damage, which has been associated with pathological findings of Alzheimer’s disease (AD), such as amyloid plaques and protein fibrils. Oxidative stress alterations, including increased production of reactive oxygen metabolites, decline of antioxidant systems, and decreased efficiency in repairing damaged molecules, have been linked to the development of AD. Postmortem studies on brain tissue from AD patients have shown several oxidative damage markers, such as increased lipid peroxidation, oxidative damage of proteins, glyco-oxidation, and reduction of antioxidant enzyme systems. Methods: We studied 40 patients referred to …

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GLUCOSE CONTROL IN THE OLDER PATIENT: FROM INTENSIVE CONTROL TO EFFECTIVE AND SAFE CONTROL

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ALTERAZIONI NUTRIZIONALI DELL’ANZIANO

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QUALITÀ DELLA VITA NEGLI ANZIANI: POSSIBILI INDICATORI

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INVECCHIAMENTO DELLA POPOLAZIONE E DINAMICHE MIGRATORIE: UNA VALUTAZIONE EPIDEMIOLOGICA, SOCIO-CULTURALE E FUNZIONALE IN PAZIENTI ANZIANI MIGRANTI

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DEPRESSIONE E AUTO PERCEZIONE DELLA SALUTE IN SOGGETTI ANZIANI ITALIANI: EUROPEAN STUDY ON ADULT WELL-BEING (ESAW)

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CGA with Easy-care: priorities for research and development.

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MALATTIA DI ALZHEIMER: PREDISPOSIZIONE, PREVENZIONE E TERAPIE FARMACOLOGICHE

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CO-MORBILITA’ E DEPRESSIONE NELL’ANZIANO

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ARE NEUROLOGISTS MORE LIKELY TO PRESCRIBE ANTITHROMBOTIC THERAPY AFTER STROKE?

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L’ALIMENTAZIONE NEI PAZIENTI ISTITUZIONALIZZANTI AFFETTI DA DEMENZA TIPO ALZHEIMER

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DOLORE E QUALITA' DELLA VITA.L'IMPORTANZA DELLA VMD

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ELEVATED HOMOCYSTEINE IS ASSOCIATED WITH LOWER HANDGRIP STRENGTH IN ELDERLY PERSONS

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USO DI IPOGLICEMIZZANTI ORALI SECRETAGOGHI E CADUTE IN PAZIENTI DIABETICI ANZIANI RICOVERATI IN UN REPARTO PER ACUTI

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PROSPECTIVE STUDY OF FAST-FOOD CONSUMPTION AND THE RISK OF GESTATIONAL DIABETES MELLITUS: THE SUN COHORT

Little is known about fast-food consumption as a risk factor for gestational diabetes mellitus (GDM). Therefore, our objective was to evaluate the association between fast-food consumption and GDM in a cohort of university graduates. The prospective dynamic SUN cohort included data of 2903 women free of diabetes or previous gestational diabetes who reported at least one pregnancy between 1999 and 2010. Fast-food consumption was assessed through a validated semi-quantitative food frequency questionnaire. Fast-food was defined as the consumption of hamburgers, sausages, and pizza. Three categories of fast food were established: low (0-3 servings/month), intermediate (>3 servings/month-2 serv…

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INDUCTION OF VEGF RELEASE BY TRANSCUTANEOUS FREQUENCY MODULATED NEURAL STIMULATION IN DIABETIC POLYNEUROPATHY

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Il percorso ideale nella gestione del paziente con osteoporosi severa:dalla valutazione del rischio all'approccio multidisciplinare

Non disponibile

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ANTIAGING STRATEGIES

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PROTEIN SUPPLEMENTATION IN FRAIL OLDER PERSONS: OFTEN NECESSARY BUT NOT ALWAYS SUFFICIENT

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COLLAGEN OVERGLYCOSYLATION: A BIOCHEMICAL FEATURE THAT MAY CONTRIBUTE TO BONE QUALITY

Skeletal ability to resist mechanical stress is determined by bone amount and quality, which relies on macro- and micro-architecture, turnover, bone matrix, and mineralisation; the role of collagen has not been clearly elucidated. Numerous post-translational steps are involved in collagen type I biosynthesis, including residue hydroxylation and glycosylation catalysed by enzymes that work until the protein folds forming the triple helix; therefore, folding rate regulates these processes. Overglycosylated hydroxylysines are poor substrates for e-amino group deamination which initiates cross-link formation. Three clinical conditions associated with fractures may relate collagen overglycosylat…

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L’IPONATRIEMIA NELL’ANZIANO: UNA PROBLEMATICA SEMPRE ATTUALE

Le alterazioni della concentrazione plasmatica del sodio rappresentano una delle disionie di più frequente riscontro nei pazienti ricoverati e che l’incidenza e la prevalenza aumentano con l’età. Molteplici fattori correlati all’invecchiamento giocano un ruolo in tal senso; ad esempio, variazioni anatomiche e funzionali, modificazioni della composizione corporea, alterazioni dei meccanismi fisiologici che regolano il metabolismo e l’omeostasi del sodio e dell’acqua. L’aumento dell’incidenza di tali disturbi nella popolazione anziana rappresenta un chiaro esempio di come l’invecchiamento è in grado di compromettere le capacità di compenso, di adattamento e l’omeostasi dell’organismo. Alterat…

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VALUTAZIONE MULTIDIMENSIONALE IN UN GRUPPO DI PAZIENTI ANZIANI IMMIGRATI

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DIETA MEDITERRANEA E LONGEVITÀ: RUOLO DELL’OLIO EXTRAVERGINE DI OLIVA

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IL PAZIENTE GERIATRICO COMPLESSO E LA SINDROME DI FRAGILITÀ: SPECIFICITÀ DELLA GERIATRIA

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INVECCHIAMENTO DELLA POPOLAZIONE NEL MAGHREB

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SEPSI IN SOGGETTI PORTATORI DI ELETTROCATETERE INTRACARDIACO

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MALATTIA DI ALZHEIMER: PREDISPOSIZONE, PREVENZIONE E TERAPIE FARMACOLOGICHE

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QUALITY OF LIFE FOR OLDER PERSONS

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COENZIMA Q E MALATTIA DI PARKINSON

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QUALITY OF LIFE IN OSTEOPOROTIC WOMEN WITH INADEQUATE RESPONSE TO ANTIRESORPTIVE DRUGS

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Ambiente e anziano: la domotica come ausilio per disabili e anziani

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TERAPIA ACUTA DEL DOLORE E CAPACITÀ FUNZIONALE IN PAZIENTI AMBULATORIALI

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IPERCALCEMIA

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PROGNOSTIC VALUE OF ESTIMATED GLOMERULAR FILTRATION RATE IN HOSPITALIZED ELDERLY PATIENTS

A multicenter observational study, REPOSI (REgustri POliterapie Società Italiana di Medicina Interna), was conducted to assess the prognostic value of glomerular filtration rate (eGFR) on in-hospital mortality, hospital readmission and death within 3 months, in a sample of elderly patients (n=1,363) admitted to 66 internal medicine and geriatric wards. Bases on eGFR, calculated by the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula, subjects at hostpital admission were classified into three groups: group 1 with normal eGFR (60 ml/min/1.73m2, reference group), group 2 with moderately reduced eGFR (30-59 ml/min/1.73 m2) and group 3 with severely reduced eGFR (<30 ml/m…

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COMORBIDITY, POLYMORBIDITY, POLYPHARMACY

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MCI ED EVOLUZIONE IN DEMENZA

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TRATTAMENTO DELLE LESIONI ULCERATIVE CUTANEE DIFFICILI: ESISTONO MARGINI DI MIGLIORAMENTO?

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VITAMIN D SUBSTRATE-PRODUCT RELATIONSHIP IN IDIOPATHIC HYPERCALCIURIA

Absorptive hypercalciuria (AH) is associated with elevated levels of 1,25-dihydroxyvitamin D (1,25(OH)(2)D). While no increase of 1,25(OH)(2)D after oral administration of 25-hydroxyvitamin D (25OHD) at high doses has been claimed in normal subjects, a substrate-product relationship has been reported in normal children, young people after UV irradiation, older persons, postmenopausal women, primary hyperparathyroidism, renal failure, osteomalacia, and sarcoidosis. No data of this relationship in AH is available. To investigate 25OHD-1,25(OH)(2)D substrate-product relationship in AH, 161 AH patients (mean age 60.9+/-11.7 years) and 110 age- and sex-matched controls (mean age 61.5+/-12.4 year…

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LA SINDROME DA IMMOBILIZZAZIONE

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MAGNESIUM METABOLISM IN HYPERTENSION AND TYPE 2 DIABETES MELLITUS

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129. MAGNESIUM METABOLISM IN INSULIN RESISTANCE, CARDIOMETABOLIC SYNDROME AND TYPE 2 DIABETES

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ORAL GLUCOSE TOLERANCE EFFECT ON INTRACELLULAR FREE MAGNESIUM IN NORMAL, DIABETIC AND HYPERTENSIVE SUBJECTS

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L’IPERCALCIURIA IDIOPATICA

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SENILE ANOREXIA IN ACUTE WARD AND REHABILITATION SETTINGS

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MAGNESIO, DIABETES Y SINDROME METABOLICO

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DEMENZA E DISTURBI DELL’ALIMENTAZIONE

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Effetti collaterali della terapia farmacologica dell'ipertensione arteriosa nel soggetto anziano

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OSTEOPOROSI E DIABETE MELLITO

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ELEVATI LIVELLI DI OMOCISTEINA E RIDOTTA FORZA MUSCOLARE IN SOGGETTI ANZIANI

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Magnesio e Invecchiamento

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ALTERAZIONI DEL METABOLISMO DEL SODIO NELL’ANZIANO: CASISTICA DI UN REPARTO DI GERIATRIA PER ACUTI

Premessa. Le alterazioni della concentrazione plasmatica del sodio rappresentano gli squilibri elettrolitici più frequenti nei pazienti ospedalizzati e l’incidenza e la prevalenza aumentano con l’età. L’invecchiamento rappresenta un fattore di rischio indipendente e molto significativo per le alterazioni del bilancio del sodio e dell’acqua. Numerosi sono i fattori che cooperano nell’aumentare la suscettibilità dell’anziano a tali squilibri, dipendendo da modificazioni fisiologiche età correlate dei meccanismi che regolano il bilancio idro-salino dell’organismo, dalla progressiva riduzione delle capacità di compenso che caratterizza il fenomeno stesso dell’invecchiamento e dalle comorbilità,…

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LONG-TERM CARE NELL’ITALIA CHE INVECCHIA

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IL SOSTEGNO AI CAREGIVER DI MALATI DI DEMENZA E/O ALZHEIMER: UNA RISORSA PER IL TRATTAMENTO EFFICACE. ESPEIENZA DI UN GRUPPO DI “AUTO-AIUTO”

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Predictors of clinical events occurring during hospital stay among elderly patients admitted to medical wards in Italy.

Abstract Background Clinical events occurring during hospital stay are independent predictors of prolonged hospitalization, in-hospital mortality and readmission among elderly patients admitted to medical wards. Purpose To identify predictors of intercurrent clinical events (ICE) during hospital stay among the main demographic, functional and clinical characteristics assessed at hospital admission in a multicenter sample of elderly inpatients in Italy. Methods This observational prospective cohort study was conducted in 66 internal and geriatric medicine hospital wards in 2010. It enrolled 1267 inpatients aged 65 years or older living at home before hospitalization. Multivariable Poisson re…

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Circulating magnesium levels and disability in elderly hospitalizated subjects

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NECESSITÀ DI UNA PERIODICA ASSISTENZA GERIATRICA DOMICILIARE. DESCRIZIONE DI UN CASO CLINICO

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TREATMENT WITH DAILY SUBCUTANEOUS TERIPARATIDE (1-34) COMPARED WITH DAILY SUBCUTANEOUS PARATHYROID HORMONE (1-84) IN WOMEN WITH SEVERE POSTMENOPAUSAL OSTEOPOROSIS: A RANDOMIZED, HEAD-TO-HEAD STUDY

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DEMENZE E RISCHIO DI FRATTURE OSTEOPOROTICHE NEGLI ANZIANI. STUDIO OSSERVAZIONALE IN UN’UNITA’ VALUTATIVA ALZHEIMER (n°6) DI PALERMO

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Rapporto tra omocisteinemia, stress ossidativo ed età

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UN NUOVO INDICE PROGNOSTICO-TERAPEUTICO IN ONCOLOGIA GERIATRICA

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FATTORI DI RISCHIO CARDIOVASCOLARI E METABOLICI NEI CENTENARI

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TERIPARATIDE: DATI DI SICUREZZA

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DEPRESSIONE E DEMENZA: STUDIO NEUROPSICOLOGICO

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DIFFICOLTÀ DI DIAGNOSI DELLA DEPRESSIONE NELL’ANZIANO

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OSTEOPOROSI MASCHILE. CASO CLINICO

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TUMORE GASTROINTESTINALE STROMALE INDIFFERENZIATO (GIST)E PREGRESSA BILLROTH II IN UN PAZIENTE ANZIANO: SOLO CAUSALITA'?

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DEPRESSION AND SELF HEALTH PERCEPTION IN ITALIAN ELDERLY SUBJECT: EUROPEAN STUDY ON ADULT WELL-BEING (ESAW)

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ANZIANI E DEPRESSIONE. COME RICONOSCERLA TEMPESTIVAMENTE

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SINTOMI COGNITIVI E DEPRESSIVI IN SOGGETTI NON DEMENTI CON MALATTIA CEREBROVASCOLARE SOTTOCORTICALE

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DEPRESSIONE, AUTOPERCEZIONE DELLA SALUTE E STATO FUNZIONALE NEL PAZIENTE ANZIANO: EUROPEAN STUDY ON ADULT WELL-BEING (ESAW)

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PARKINSON E DEMENZA : VALUTAZIONE COMPARATIVA TRA INDICI NEUROPSICOLOGICI E NEURORADIOLOGICI

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ASSOCIAZIONE TRA LIVELLI DI MAGNESIO ED ORMONI ANABOLICI NEL SOGGETTO ANZIANO DI SESSO MASCHILE

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IL DISTURBO DA PANICO NEGLI ANZIANI

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FRATTURE OSTEOPOROTICHE IN PAZIENTI CON DEMENZA

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Terapia con ipoglicemizzanti orali secretagoghi in pazienti anziani diabetici ricoverati in acuto

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FRAGILITY FRACTURES IN OLDER PERSONS WITH ALTERED THYROID FUNCTION

Gli ormoni tiroidei sono peptidi che svolgono molteplici e complesse funzioni nell’organismo umano. Lo sche-letro è uno dei tessuti bersaglio degli ormoni tiroidei, ed una loro carenza o un loro eccesso ha importanti conseguenze sul tessuto osseo soprattutto nel periodo dello sviluppo e durante l’invecchiamento. I disturbi a carico della tiroide si osservano con maggior frequenza nei soggetti in età avanzata rispetto ai giovani. La tire-otossicosi è una causa nota di osteoporosi secondaria. L’ipertiroidismo conclamato e l’ipertiroidismo iatrogeno dovuto ad un eccesso nel dosaggio della terapia sostitutiva con ormoni tiroidei sono possibili cause di fratture ossee da fragilità. L’ipertiroidi…

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IPOTENSIONE ORTOSTATICA NELL’ANZIANO: PREVALENZA IN UNA NOSTRA CASISTICA DI PAZIENTI RICOVERATI IN REGIME DI DAY HOSPITAL

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Determinants of adherence to osteoporosis treatment in clinical practice.

Introduction: Poor adherence to prescribed treatments is widespread in clinical practice and this can lead to potentially life-threatening events. This problem is apparently very common for osteoporosis treatment but the causes of discontinuation and low compliance are complex and poorly defined. Methods: Global adherence to osteoporosis treatment was specifically addressed in a nation-wide survey carried out in 9851 postmenopausal women referred to 141 Italian centres for osteoporosis management for a follow-up assessment, at least one year after having been prescribed a treatment with one of the following drugs: calcium±vitamin D supplements alone (CaVitD), hormone replacement therapy (HR…

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Prevalenza dell’anoressia nel paziente anziano in ospedale.

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DIAGNOSING AND MANAGING THYROID DISEASE IN THE NURSING HOME

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ANEMIA NELL’ANZIANO: PREVALENZA IN UNA POPOLAZIONE DI SOGGETTI GERIATRICI OSPEDALIZZATI

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EFFECTS OF POLYENOIC OMEGA 3 FATTY ACIDS ON OXIDATIVE STRESS IN HYPERTENSIVE HELDERLY SUBJECTS

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L’ASSISTENZA SANITARIA ALLA POPOLAZIONE ANZIANA IN ITALIA: IL PROGETTO U.L.I.S.S.E. (UN LINK INFORMATICO SUI SERVIZI SANITARI ESISTENTI PER L’ANZIANO)

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POLIMIALGIA REUMATICA

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IDROCEFALO CRONICO NELL’ANZIANO: CASO CLINICO

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Combination of intensive cognitive rehabilitation and donepezil therapy in Alzheimer’s disease.

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Health care for older people in Italy: The U.L.I.S.S.E. Project (Un link informatico sui servizi sanitari esistenti per l'anziano - a computerized network on health care services for older people).

OBJECTIVES: The U.L.I.S.S.E. study is aimed at describing older patients who are cared for in hospitals, home care or nursing homes in Italy. DESIGN: The U.L.I.S.S.E. study is an observational multicenter prospective 1-year study. SETTING: Overall, 23 acute geriatric or internal medicine hospital units, 11 home care services and 31 nursing homes participated in the study. MEASUREMENTS: The patient's evaluation was performed using comprehensive geriatric assessment instruments, i.e. the interRAI Minimum Data Set, while data on service characteristics were recorded using ad-hoc designed questionnaires. RESULTS: The older subjects who are in need of acute and long term care in Italy have simil…

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IPOTIROIDISMO POST AMIODARONE, DETERIORAMENTO COGNITIVO E FIBRILLAZIONE ATRIALE

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CORRELAZIONI TRA RISCHIO DI CADUTE E UTILIZZO DI NEUROLETTICI IN PAZIENTI ISTITUZIONALIZZANTI

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ONE HUNDRED YEARS OF… HEALTH! MEDITERRANEAN DIET AND LONGEVITY: ROLE OF OLIVE OIL.

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INVECCHIAMENTO DELLA POPOLAZIONE E DINAMICHE MIGRATORIE: UNA VALUTAZIONE EPIDEMIOLOGICA, SOCIO-CULTURALE E FUNZIONALE IN PAZIENTI ANZIANI MIGRANTI

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OSTEOPOROSI NELL’ANZIANO: UPDATE SULLE TERAPIE FARMACOLOGICHE E NON FARMACOLOGICHE

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HEALTHY LONGEVITY THANKS TO THE MEDITERRANEAN DIET

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HOSPICE E TERMINALITÀ IN PAZIENTI CON DEMENZA

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MAGNESIUM METABOLISM IN INSULIN RESISTANCE, CARDIOMETABOLIC SYNDROME AND TYPE 2 DIABETES

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TUMORE GASTROINTESTINALE STROMALE INDIFFERENZIATO (GIST) E PREGRESSA BILLROTH II IN UN PAZIENTE ANZIANO: SOLO CASUALITÀ?

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TERAPIE DI RIABILITAZIONE COGNITIVA NEL COMPLESSO PARKINSON-DEMENZA NELL’ANZIANO. Caso clinico

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DELIRIUM DURANTE LA DEGENZA OSPEDALIERA IN UN REPARTO GERIATRICO

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EFFECTS OF POLYENOIC OMEGA-3 FATTY ACIDS ON OXIDATIVE STRESS IN HYPERTENSIVE ELDERLY SUBJECTS

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LE IPERNATRIEMIE NELL’ANZIANO

L’pernatremia è caratterizzata da un deficit di acqua corporea totale rispetto al sodio ed è definita da una concentrazione plasmatica superiore a 145 mmol/L. L’ipersodiemia nella popolazione geriatrica è un disturbo comune, associato ad una significativa morbilità e mortalità. Le persone anziane sono predisposte a sviluppare ipernatriemia a causa di modificazioni fisiologiche legate all'età: ad esempio la diminuzione della sete, una ridotta capacità di concentrazione delle urine e la diminuzione del contenuto di acqua corporea totale. I farmaci possono aumentare questa predisposizione. Nelle case di cura e di riposo, l’ipernatremia e la disidratazione sono considerate prevenibili, per cui …

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MIGRATION, CARDIOVASCULAR RISK AND BLOOD PRESSURE MODIFICATIONS

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LA DEPRESSIONE NELL’ANZIANO. NOSTRO STUDIO SU 100 SOGGETTI

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Cien años de... ¡salud, dieta mediterránea y longevidad: el papel del aceite de olivas

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Magnesium and aging.

Over the past decades, the clinical relevance and biological significance of magnesium (Mg) have been documented. Deficiency in Mg, aside from having a negative impact on the energy production pathway required by mitochondria to generate ATP, also reduces the threshold antioxidant capacity of the aging organism and its resistance to free-radical damage. Mg also acts as an antioxidant against free radical damage of the mitochondria. Chronic inflammation and oxidative stress have both been identified as pathogenic factors in aging and in several age-related diseases. Chronic Mg deficiency results in excessive production of oxygen-derived free radicals and low grade inflammation. Aging is very…

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RELAZIONE TRA M. DI PARKINSON E DEMENZA DI ALZHEIMER. CASO CLINICO

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MALATTIA OSSEA DI PAGET

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DISTURBI D’ANSIA NELL’ANZIANO

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IL DOLORE NELLA DEMENZA. STUDIO SU 100 PAZIENTI

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DELIRIUM, ANZIANI E OSPEDALE

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116. LESIONI ULCERATIVE CUTANEE: PROGETTO PILOTA PER IL TRATTAMENTO INTEGRALE AMBULATORIALE E TERRITORIALE INCLUDENDO STIMOLAZIONE ELETTRICA FREMS. MIGLIORAMENTI CLINICI E RIDUZIONE DEI COSTI

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L'azitromicina nella gastroparesi diabetica in una donna anziana ospedalizzata

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THE IMPORTANCE OF TIGHT BLOOD PRESSURE CONTROL IN DIABETIC HYPERTENSIVE PATIENTS

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IL RANK LIGANDO QUALE TARGET TERAPEUTICO NEL TRATTAMENTO DELLE PAZIENTI ANZIANE CON OSTEOPOROSI

Cortical and trabecular bone undergo a continuous and balanced remodeling process, which consists of a phase of resorption, mediated by osteoclasts, and a phase of neoformation mediated by osteoblasts. The activity of both, osteoblasts and osteoclasts, is regulated by the osteocytes, which are the most abundant cells in bone tissue. An imbalance of this process with an excessive resorption activity causes a loss of bone mass and microarchitectural deterioration of the skeleton, with consequent reduction of bone strength and increased risk of fractures. The ligand for the “Receptor Activator of Nuclear Factor Kappa- B” (RANK-L), a protein expressed by osteoblasts, plays a fundamental role in…

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OSTEOPOROSI MASCHILE: UN CASO DI PARAPARESI CONSEGUENTE A MIELOPATIA DORSALE DA FRATTURA VERTEBRALE SEVERA

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M.P.S. e M.C.I. segni e sintomi

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CORRELAZIONE TRA LLC-B E INFEZIONE DA HCV NELL’ANZIANO.

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ENVEJECER SIN VOLVERSE VIEJO. SIGLO XXI Y ENVEJECIMIENTO: LA GERIATRIA, UNA ESPECIALIDAD EN CRECIMIENTO

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MAGNESIUM AND ALZHEIMER’S DISEASE: IMPLICATIONS FOR DIET AND NUTRITION

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ECOCOLORDOPPLER EPIAORTICO E TRANSCRANICO NELLA DIAGNOSI DIFFERENZIALE DELLE DEMENZE

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VALUTAZIONE EPIDEMIOLOGICA NEL TERRITORIO DI PALERMO E PROVINCIA SULL’UTILIZZO DEI FARMACI NELLA TERAPIA DEL DOLORE ALLA LUCE DELLE NUOVE NORMATIVE

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Depressione e m. diParkinson: valutazione del tono dell' umore in 20 pazienti ultrasettantenni in trattamento con L-DOPA e/o dopamino-agonisti. Dati preliminari

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HOMOCYSTEINE AND OXIDATIVE STRESS IN HYPERTENSIVE AND DIABETIC OLDER PATIENTS

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IN-HOSPITAL COMPLICATIONS OF ACUTE MYOCARDIAL INFARCTION IN HYPERTENSIVE SUBJECTS

BACKGROUND: Recent studies have shown a worse in-hospital outcome in hypertensive than in normotensive patients with acute myocardial infarction (AMI), which has been attributed to more frequent complications. The aim of this study was to investigate clinical patterns, risk factors, and in-hospital complications in hypertensive and normotensive patients with AMI. METHODS: Of 4994 consecutive patients with AMI admitted to the intensive care unit, hypertensive patients with first infarction (n = 915; mean age 68.8 +/- 11.4 years) and 915 gender- and age-matched normotensive subjects were retrospectively studied. RESULTS: In the univariate analysis, hypertensive subjects presented more frequen…

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Correlazione tra LLC-B e infezione da HCV nell'anziano. Descrizione di un caso clinico.

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SOMMINISTRAZIONE ORALE DI MAGNESIO E FUNZIONE ENDOTELIALE IN ANZIANI DIABETICI E IPERTESI

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LESIONI ULCERATIVE DIABETICHE E DA DECUBITO: PROGETTO PILOTA PER IL TRATTAMENTO INTEGRALE AMBULATORIALE E TERRITORIALE INCLUDENDO STIMOLAZIONE ELETTRICA CON FREQUENZA E AMPIEZZA MODULATE (FREMS: FREQUENCY MODULATED ELECTRO-MAGNETIC NEURAL STIMULATION).

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CONSEGUENZE A LUNGO TERMINE DELLE FRATTURE DA FRAGILITÀ

La riduzione della resistenza ossea che predispone le persone affette ad un aumentato rischio di fratture e di disabilità è molto frequente nell’anziano. L'età avanzata è un fattore di rischio anche per le cadute che di solito si associano all’evento fratturativo. Dopo una frattura di femore circa il 5% delle persone muore nel periodo immediatamente successivo, ~20% muore entro un anno, ~30% rimane disabile, ~40% non recupera più la propria autonomia e 12-20% richiede l’istituzionalizzazione. L’impatto delle fratture femorale a lungo termine è particolarmente severo negli anziani fragili. Le fratture vertebrali possono causare dolore cronico, deformità, disfagia e ridotta funzionalità polmo…

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Osteoporosi nell’anziano.

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IL DOLORE NELLA DEMENZA

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IL CONTROLLO GLICEMICO NELL’ANZIANO DIABETICO: COSA CI INSEGNANO I RISULTATI DEI TRIALS?

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LESIONI ULCERATIVE CUTANEE: PROGETTO PILOTA PER IL TRATTAMENTO INTEGRALE TERRITORIALE INCLUDENDO STIMOLAZIONE ELETTRICA FREMS. MIGLIORAMENTI CLINICI E RIDUZIONE DEI COSTI

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MISURARE LA FRAGILITÀ DEL PAZIENTE ONCOLOGICO ANZIANO

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BPCO E OSTEOPOROSI

COPD and osteoporosis are frequently associated because they have common risk factors, including age, smoking habits and reduced physical activity. COPD is also characterized by systemic inflammation, malnutrition (up to cachexia), hypovitaminosis D, and the use of local and systemic corticosteroids, all of which could cause deterioration in bone quality with a consequent increase in fragility fractures. These fractures may further impair mobility and increase disability and mortality. The vertebral and rib fractures can directly further affect lung function and promote exacerbations. As a result, the assessment of fracture risk in patients with COPD is of vital importance from the earliest…

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INSULIN RESISTANCE AND CARDIOMETABOLIC SYNDROME IN HIV INFECTION

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Omega-3 Fatty Acid Supplementation and Oxidative Stress in Hypertensive Older Subjects

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IL DOLORE NELLA DEMENZA. STUDIO SU 100 PAZIENTI

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THE IMPORTANCE OF TIGHT BLOOD PRESSURE CONTROL IN DIABETIC HYPERTENSIVE PATIENTS

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