0000000000103058

AUTHOR

M Williams

showing 12 related works from this author

Analysis of transverse momentum correlations in hadronic Z decays

1999

In a recent paper, evidence was presented for a significant, positive correlation between the total transverse momenta of particles on opposite hemispheres of hadronic events. A new, model independent analysis of the data has been made. Two components can be distinguished in the correlation, and quantitative estimates of each are given. The results form a significant test of Monte Carlo models and some of the physics behind them. (C) 1999 Published by Elsevier Science B.V. All rights reserved.

PhysicsNuclear and High Energy Physics[PHYS.HEXP] Physics [physics]/High Energy Physics - Experiment [hep-ex]010308 nuclear & particles physicsHadronMonte Carlo methodLEPPositive correlation01 natural sciencesALEPH Experiment; LEP; hadronic Z decaysALEPH ExperimentNuclear physicsTransverse plane0103 physical sciencesTransverse momentum[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]hadronic Z decays010306 general physicsParticle Physics - Experiment
researchProduct

Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

2019

Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery.A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a c…

Malerenal failureTime Factorsmedicine.medical_treatmentAdult; Aged; Anti-Inflammatory Agents Non-Steroidal; Elective Surgical Procedures; Female; Humans; Ileus; Kaplan-Meier Estimate; Male; Middle Aged; Patient Safety; Postoperative Care; Postoperative Complications; Proportional Hazards Models; Prospective Studies; Recovery of Function; Time Factors; Treatment Outcome; Colectomy; ProctectomyAnti-Inflammatory Agentscolorectal surgery; ileus; non-steroidal anti-inflammatory drugs; NSAIDSKaplan-Meier Estimate030230 surgeryTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]0302 clinical medicinePostoperative ComplicationsProspective StudiesProspective cohort studyColectomyColorectalColectomyRISKProctectomyHazard ratioAnti-Inflammatory Agents Non-SteroidalAcute kidney injuryMiddle AgedColorectal surgeryNSAIDTreatment OutcomeElective Surgical Procedures030220 oncology & carcinogenesisFemalePatient SafetyNon-SteroidalCohort studyAdultcolorectal Surgery ileus non-steroidal anti-inflammatory drugsmedicine.medical_specialtyIleusNon‐steroidal anti‐inflammatory drugs. NSAIDs. Postoperative ileus. Colorectal surgery.ACUTE KIDNEY INJURYanti-inflammatory agents03 medical and health sciencesIleusInternal medicinemedicineHumansAdverse effectAgedProportional Hazards Modelsnon-steroidal anti-inflammatory drugs - ileus - colorectal surgeryPostoperative Carebusiness.industryRecovery of Functionmedicine.diseaseSettore MED/18 - Chirurgia Generalecolorectal cancer.Surgerycolorectal surgerybusiness
researchProduct

Limits on neutral Higgs boson production in the forward region in $pp$ collisions at $\sqrt{s} = 7$ TeV

2013

Limits on the cross-section times branching fraction for neutral Higgs bosons, produced in p p collisions at root s = 7 TeV, and decaying to two tau leptons with pseudorapidities between 2.0 and 4.5, are presented. The result is based on a dataset, corresponding to an integrated luminosity of 1.0 fb(-1), collected with the LHCb detector. Candidates are identified by reconstructing final states with two muons, a muon and an electron, a muon and a hadron, or an electron and a hadron. A model independent upper limit at the 95% confidence level is set on a neutral Higgs boson cross-section times branching fraction. It varies from 8.6 pb for a Higgs boson mass of 90 GeV to 0.7 pb for a Higgs bos…

GravitacióSEARCH; MSSM; LHCHadronStandard-model Higgs boson7. Clean energy01 natural sciencesHigh Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareHigh Energy Physics - Experiment (hep-ex)[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Teoria quànticaNuclear ExperimentQCBosonPhysicsHiggs physicsQuantum field theoryHiggs bosonProduction (computer science)Física nuclearLHCHadron-induced high- and super-high-energy interactions (energy > 10 GeV): Inclusive production with identified leptons photons or other nonhadronic particlesParticle Physics - ExperimentGravitationParticle physicsTeoria quàntica de campsNuclear and High Energy PhysicsFOS: Physical sciencesStandard-model Higgs bosons; Supersymmetric Higgs bosons; Hadron-induced high- and super-high-energy interactions (energy > 10 GeV): Inclusive production with identified leptons photons or other nonhadronic particlesHadronsPartícules (Física nuclear)Standard ModelSEARCH0103 physical sciences010306 general physicsLarge Hadron Collider (France and Switzerland)Standard-model Higgs bosonsMuonHadron-Hadron Scattering010308 nuclear & particles physicsBranching fractionComputer Science::Information RetrievalHadron-Hadron Scattering; Higgs physicsHigh Energy Physics::PhenomenologyGran Col·lisionador d'HadronsHiggs physicSupersymmetric Higgs bosonSupersymmetric Higgs bosonsQuantum theoryHadron-Hadron Scattering; Higgs physics; Nuclear and High Energy PhysicsHigh Energy Physics::ExperimentMSSMLepton
researchProduct

Safety of hospital discharge before return of bowel function after elective colorectal surgery

2020

Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multiva…

operativeMalepostoperative dischargePostoperative Complications0302 clinical medicineColostomyCRITERIAProspective StudiesBowel functionColectomyIMAGINEstomaintestinesProctectomyIleostomydigestive oral and skin physiologypatient dischargecolorectal surgery hospital discharge bowel functionRECOVERYMiddle Agedadult; colostomy; elective surgical procedures; female; follow-up studies; humans; ileostomy; ileus; male; middle aged; multivariate analysis; patient discharge; patient readmission; patient safety; postoperative complications; prospective studies; recovery of function; colectomy; proctectomyPatient DischargeColorectal surgeryileus - - discharge - bowel function - elective - colorectal surgeryElective Surgical Procedures030220 oncology & carcinogenesisFemale030211 gastroenterology & hepatologyPatient SafetyCohort studysafetyAdultmedicine.medical_specialtyIleusPatient Readmissiondefecation03 medical and health sciencesIleuspostoperative complicationsmedicineHospital dischargeHumanscolorectal surgery; postoperative discharge; IMAGINE; stomacolorectal resectionColorectal resectiondefecation postoperative complications colorectal surgery intestines patient discharge patient readmission safety surgical procedures operative colorectal resection ileusbusiness.industryRecovery of FunctionOdds ratiomedicine.diseasedigestive system diseasessurgical proceduresSurgeryMultivariate AnalysisDefecationcolorectal surgerySurgerybusinessFollow-Up Studies
researchProduct

Evaluation of appendicitis risk prediction models in adults with suspected appendicitis.

2019

Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (pro…

AdulthumanosDecision MakingRisk AssessmentNOapendicectomíaapendicitisevaluación de riesgosAppendectomyHumanshospitalGeneralcollaborativeLS7_4right iliac fossa; appendicitis; collaborativeemergency serviceOriginal Articlesadultoright iliac fossaAppendicitisadult; appendectomy; appendicitis; humans; risk assessment; decision making; emergency service; hospitalLower GIOriginal Articleappendicitis prediction models right iliac fossa painEmergency Service Hospitaltoma de decisiónThe British journal of surgery
researchProduct

Measurement of the W mass in e+e− collisions at 183 GeV

1999

Abstract The mass of the W boson is obtained from reconstructed invariant mass distributions in W-pair events. The sample of W pairs is selected from 57 pb−1 collected with the ALEPH detector in 1997 at a centre-of-mass energy of 183 GeV. The invariant mass distributions of reweighted Monte Carlo events are fitted separately to the experimental distributions in the q q q q and all lν q q channels to give the following W masses: m W hadronic =80.461±0.177 (stat.) ±0.045 (syst.) ±0.056 (theory) GeV /c 2 , m W semileptonic =80.326±0.184 (stat.) ±0.040 (syst.) GeV /c 2 , where the theory error represents the possible effects of final state interactions. The combination of these two measurements…

PhysicsNuclear and High Energy PhysicsParticle physicsAleph[PHYS.HEXP] Physics [physics]/High Energy Physics - Experiment [hep-ex]010308 nuclear & particles physicsElectron–positron annihilationHadronMonte Carlo methodState (functional analysis)LEP01 natural sciencesNuclear physicsALEPH ExperimentPair productionALEPH Experiment; LEP; W boson0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]W bosonInvariant massHigh Energy Physics::Experiment010306 general physicsNuclear ExperimentALEPH experimentParticle Physics - Experiment
researchProduct

Search for CP violation in D (+/-) -> (KSK +/-)-K-0 and D-s(+/-) -> K-S(0)pi(+/-) decays

2014

A search for \CP violation in Cabibbo-suppressed $D^{\pm}\rightarrow K^0_{\mathrm{S}} K^{\pm}$ and $D^{\pm}_{s}\rightarrow K^0_{\mathrm{S}} \pi^{\pm}$ decays is performed using $pp$ collision data, corresponding to an integrated luminosity of 3~fb$^{-1}$, recorded by the LHCb experiment. The individual $CP$-violating asymmetries are measured to be \begin{eqnarray*} \mathcal{A}_{CP}^{D^{\pm}\rightarrow K^0_{\mathrm{S}} K^{\pm}} & = & (+0.03 \pm 0.17 \pm 0.14) \% \mathcal{A}_{CP}^{D^{\pm}_{s}\rightarrow K^0_{\mathrm{S}} \pi^{\pm}} & = & (+0.38 \pm 0.46 \pm 0.17) \%, \end{eqnarray*} assuming that $CP$ violation in the Cabibbo-favoured decays is negligible. A combination of the measured asymmet…

Nuclear and High Energy PhysicsParticle physicsSDG 16 - Peacemedia_common.quotation_subjectCP violation; Hadron-Hadron ScatteringDalitz plotLHCb - Abteilung HofmannHadrons01 natural sciencesAsymmetryNOSettore FIS/04 - Fisica Nucleare e SubnucleareNuclear physicsTEV PP COLLISIONS; PRODUCTION ASYMMETRY0103 physical sciencesCP violation hadron-hadron scatteringPiTEV PP COLLISIONS010306 general physicsLarge Hadron Collider (France and Switzerland)PRODUCTION ASYMMETRYQCmedia_commonPhysicsLuminosity (scattering theory)Hadron-Hadron Scattering010308 nuclear & particles physicshep-exSDG 16 - Peace Justice and Strong InstitutionsHigh Energy Physics::PhenomenologyGran Col·lisionador d'HadronsParticle physicsPhi meson/dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutionsJustice and Strong InstitutionsCP violationCP violationHigh Energy Physics::ExperimentFísica nuclearFísica de partículesExperimentsParticle Physics - Experiment
researchProduct

Measurement of polarization amplitudes and CP asymmetries in B 0 → Φk *(892)0

2014

An angular analysis of the decay $B^0 \to \phi K^*(892)^0$ is reported based on a $pp$ collision data sample, corresponding to an integrated luminosity of 1.0 fb$^{-1}$, collected at a centre-of-mass energy of $\sqrt{s} = 7$ TeV with the LHCb detector. The P-wave amplitudes and phases are measured with a greater precision than by previous experiments, and confirm about equal amounts of longitudinal and transverse polarization. The S-wave $K^+ \pi^-$ and $K^+K^-$ contributions are taken into account and found to be significant. A comparison of the $B^0 \to \phi K^*(892)^0$ and $\bar{B}^0 \to \phi \bar{K}^*(892)^0$ results shows no evidence for direct CP violation in the rate asymmetry, in th…

B physic12.15.MmB physicsLuminosityHigh Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareNeutral current13.88.+ePolarization[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]TOOLmedia_commonPhysicsPhysicsPHYSICS PARTICLES & FIELDSParticle physicsCharge conjugation parity time reversal and other discrete symmetriePolarization (waves)Transverse planeAmplitudeCP violationPhysical SciencesCP violationFísica nuclearLHCParticle Physics - ExperimentParticle physicsNuclear and High Energy Physicsmedia_common.quotation_subject14.40.NdFlavour Changing Neutral CurrentsLHCb - Abteilung HofmannHadronsAsymmetryDECAYSHadronic decays of bottom mesonDISTRIBUTIONSLarge Hadron Collider (France and Switzerland)B physics; CP violation; Flavour Changing Neutral Currents; Hadron-Hadron Scattering; Polarization; Nuclear and High Energy PhysicsScience & TechnologyFlavour Changing Neutral CurrentHadron-Hadron ScatteringB physics; CP violation; Flavour Changing Neutral Currents; Hadron-Hadron Scattering; PolarizationGran Col·lisionador d'HadronsLHCb13.25.HwBottom mesons (|B|>0)11.30.ErHigh Energy Physics::ExperimentFísica de partículesExperimentsPolarization in interactions and scatteringEnergy (signal processing)Bar (unit)
researchProduct

Search for invisible Higgs boson decays in e+e- collisions at centre-of-mass energies up to 184 GeV

1999

In a data sample of 78.3 pb(-1) collected in 1996 and 1997 by the ALEPH detector at centre-of-mass energies from 161 to 184 GeV, invisible decays of a Higgs boson have been searched for in the reaction e(+)e(-) --> hZ, where the Z can decay into e(+)e(-), mu(+) mu(-) or . No evidence for a signal is found and limits on the production cross section are derived as a function of the Higgs boson mass. These results are combined with those obtained in an update of the analyses of the ALEPH data taken at LEP 1. For a production cross section equal to that of the minimal standard model Higgs boson, masses below 80 GeV/c(2) are excluded at 95% C.L. (C) 1999 Elsevier Science B.V. All rights reserved.

PhysicsNuclear and High Energy PhysicsAlephParticle physics[PHYS.HEXP] Physics [physics]/High Energy Physics - Experiment [hep-ex]010308 nuclear & particles physicsHiggs bosonElectron–positron annihilationHigh Energy Physics::PhenomenologyLEPALEPH Experiment; LEP; Higgs boson01 natural sciencesStandard ModelNuclear physicsALEPH Experiment0103 physical sciencesHiggs boson[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]High Energy Physics::Experiment010306 general physicsALEPH experimentParticle Physics - Experiment
researchProduct

Angular analysis of charged and neutral B → Kμ + μ − decays

2014

The angular distributions of the rare decays B → K+µ+µ- and B0 → K0 <inf>a</inf>Sμ+μ- are studied with data corresponding to 3 fb-1 of integrated luminosity, collected in proton-proton collisions at 7 and 8TeV centre-of-mass energies with the LHCb detector. The angular distribution is described by two parameters, FH and the forward-backward asymmetry of the dimuon system AFB, which are determined in bins of the dimuon mass squared. The parameter F<inf>H</inf> is a measure of the contribution from (pseudo)scalar and tensor amplitudes to the decay width. The measurements of A<inf>FB</inf> and F<inf>H</inf> reported here are the most precise to d…

B physic12.15.MmB physicsSettore FIS/04 - Fisica Nucleare e SubnucleareLuminosityNeutral currentFlavor physicsMathematics::ProbabilityNuclear Experimentmedia_commonPhysicsB physics; Flavor physics; Flavour changing neutral currents; Hadron-hadron scattering; Rare decayPhysicsPHYSICS PARTICLES & FIELDSParticle physicsAmplitudePhysical SciencesFísica nuclearLHCNuclear and High Energy PhysicsParticle physicsmedia_common.quotation_subject14.40.NdScalar (mathematics)Flavour Changing Neutral CurrentsMathematics::Analysis of PDEsLHCb - Abteilung HofmannHadronsMeasure (mathematics)AsymmetryMathematics::Numerical AnalysisStandard ModelAngular distributionTheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITYLeptonic semileptonic and radiative decays of bottom mesonSDG 7 - Affordable and Clean EnergyTensorLarge Hadron Collider (France and Switzerland)Science & Technology/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energyHadron-Hadron ScatteringGran Col·lisionador d'HadronsFlavour changing neutral currentLHCbRare decay13.20.HeFlavor physicBottom mesons (|B|>0)High Energy Physics::ExperimentFísica de partículesExperiments
researchProduct

Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients

2017

Item does not contain fulltext BACKGROUND: Bococizumab is a humanized monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9) and reduces levels of low-density lipoprotein (LDL) cholesterol. We sought to evaluate the efficacy of bococizumab in patients at high cardiovascular risk. METHODS: In two parallel, multinational trials with different entry criteria for LDL cholesterol levels, we randomly assigned the 27,438 patients in the combined trials to receive bococizumab (at a dose of 150 mg) subcutaneously every 2 weeks or placebo. The primary end point was nonfatal myocardial infarction, nonfatal stroke, hospitalization for unstable angina requiring urgent re…

MaleSTATIN THERAPYAnticholesteremic Agents/adverse effectsAntibodieVascular damage Radboud Institute for Health Sciences [Radboudumc 16]Injections Subcutaneous/adverse effects030204 cardiovascular system & hematologyBococizumablaw.inventionPCSK90302 clinical medicineRandomized controlled triallawRisk FactorsGENETIC-VARIANTSCardiovascular DiseaseMonoclonalAnticholesteremic Agent030212 general & internal medicineMyocardial infarctionTreatment FailureHumanizedProprotein Convertase 9/antagonists & inhibitorsMedicine(all)Antibodies; Antibodies Monoclonal Humanized; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol LDL; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Injections Subcutaneous; Lipids; Male; Middle Aged; Proprotein Convertase 9; Risk Factors; Treatment Failure; Medicine (all)Anticholesteremic AgentsMedicine (all)PCSK9 InhibitorsAntibodies; antibodies monoclonal humanized; anticholesteremic agents; cardiovascular diseases; cholesterol LDL; double-blind method; female; follow-up studies; humans; hypercholesterolemia; injections subcutaneous; lipids; male; middle aged; proprotein convertase 9; risk factors; treatment failure; medicine (all)Vascular damage Radboud Institute for Molecular Life Sciences [Radboudumc 16]General MedicineLipidMiddle AgedLipids3. Good healthLDL/bloodMulticenter StudyCholesterolTRIALSCholesterol LDL/bloodCardiovascular DiseasesAntibodies Monoclonal Humanized/adverse effectsanticholesteremic agentsRandomized Controlled Trialsubcutaneouslipids (amino acids peptides and proteins)FemaleProprotein Convertase 9Cardiovascular Diseases/prevention & controlREDUCING LIPIDSHumanmedicine.medical_specialtyanimal structuresInjections SubcutaneousHypercholesterolemiaHypercholesterolemia/drug therapyPlaceboAntibodies Monoclonal HumanizedInjections SubcutaneouAntibodiesLDLInjectionsFollow-Up StudielipidsEVENTS03 medical and health sciencesantibodies monoclonal humanizedDouble-Blind MethodInternal medicinemedicineJournal ArticleHumansComparative StudyMETAANALYSISAlirocumabbusiness.industryUnstable anginaLipids/bloodPCSK9Risk FactorfungiAntibodies/bloodCholesterol LDLta3121medicine.diseaseSurgerycardiovascular diseasesEvolocumabREDUCTIONHumanized/adverse effectsSubcutaneous/adverse effectsbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyFollow-Up Studies
researchProduct

Measurement of the B-0 -> K*(0) e(+) e(-) branching fraction at low dilepton mass

2013

The branching fraction of the rare decay B-0 -> K*(0) e(+) e(-) in the dilepton mass region from 30 to 1000 MeV/c(2) has been measured by the LHCb experiment, using pp collision data, corresponding to an integrated luminosity of 1.0 fb(-1), at a centre-of-mass energy of 7 TeV. The decay mode B-0 -> J/psi (e(+) e(-)) K*(0) is utilized as a normalization channel. The branching fraction B(B-0 -> K*(0) e(+) e(-)) is measured to be B(B-0 -> K*(0) e(+) e(-))(30-1000 MeV/c2) = (3.1(-0.8)(-0.3)(+0.9)(+0.2) +/- 0.2) x 10(-7) where the fi rst error is statistical, the second is systematic, and the third comes from the uncertainties on the B-0 -> J/K*(0) and J/psi -> e(+) e(-) branching fractions.

Nuclear and High Energy PhysicsParticle physicsB physicModels beyond the standard modelFlavour Changing Neutral CurrentsFOS: Physical sciencesHadrons01 natural sciencesDECAYSB physicsPartícules (Física nuclear)High Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareNeutral currentHigh Energy Physics - Experiment (hep-ex)Neutral currents0103 physical sciencesLeptonic semileptonic and radiative decays of bottom meson[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]TOOLDECAYS; TOOL010306 general physicsLarge Hadron Collider (France and Switzerland)QCPhysicsFlavour Changing Neutral CurrentHadron-Hadron Scattering010308 nuclear & particles physicsBranching fractionB physics; Branching fraction; Flavour Changing Neutral Currents; Hadron-Hadron Scattering; Rare decayHigh Energy Physics::PhenomenologyGran Col·lisionador d'Hadrons3. Good healthCromodinàmica quànticaFIS/01 - FISICA SPERIMENTALERare decayB physics; Branching fraction; Flavour Changing Neutral Currents; Hadron-Hadron Scattering; Rare decay; Nuclear and High Energy PhysicsBottom mesons (|B|>0); Leptonic semileptonic and radiative decays of bottom mesons; Neutral currents; Models beyond the standard modelLeptonic semileptonic and radiative decays of bottom mesonsBottom mesons (|B|>0)Branching fractionHigh Energy Physics::ExperimentFísica nuclearDECAYParticle Physics - ExperimentQuantum chromodynamics
researchProduct