0000000000103859
AUTHOR
G Vizzini
Come monitorare e analizzare i tassi d'infezione in un centro trapianti d'organo solido
Le infezioni rappresentano un’importante causa di mortalità e morbilità nei pazienti trapiantati d’organo solido. Per conoscere il numero e l’impatto di queste complicanze in ambiente ospedaliero è necessario implementare un sistema di monitoraggio di tutte le infezioni correlate alle pratiche assistenziali (ICPA) mettendole in relazione con altre informazioni legate al ricovero.
Lamivudine monoprophylaxis for de novo HBV infection in HBsAg-negative recipients with HBcAb-positive liver grafts.
We followed the efficacy of long-term lamivudine monotherapy in preventing development of de novo hepatitis B (DNHB) in a large cohort of hepatitis B surface antigen (HBsAg)-negative recipients with grafts from hepatitis B core antibody (HBcAb)-positive donors. Recipients were observed over a long follow-up. Between July 1999 and December 2008, 45 patients (median age 54, range 19-67) who were HBsAg negative before transplantation were included in the study of monoprophylaxis with lamivudine starting on post-operative day 1, and continuing for life. Mean follow-up: 37.9 months; median 32.1 months (range 2.4-117). No suspension of therapy was reported during the study. Post-transplantation, …
Prevalence and risk factors for advanced liver fibrosis in HIV/HCV-coinfected individuals
ACUTE VOLUME EXPANSION AND TIPS FAILS TO INDUCE CHANGES OF IMPENDING HEART FAILURE IN PATIENTS WITH REFRACTORY ASCITES
To evaluate in patients with cirrhosis requiring an elective TIPS for refractory ascites, if acute volume expansion may elicit signs of impending heart failure, and if this can predict hemodynamic changes occurring after TIPS.