0000000000103909

AUTHOR

J Hedner

showing 5 related works from this author

Consensus document on the management of patients with obstructive sleep apnea and hypertension.

2010

hypertension sleep disordered breathingSettore MED/10 - Malattie Dell'Apparato Respiratorio
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Diabetes mellitus prevalence and control in sleep-disordered breathing: The European Sleep Apnea Cohort (ESADA) study

2014

BACKGROUND: OSA is associated with an increased risk of cardiovascular morbidity. A driver of this is metabolic dysfunction and in particular type 2 diabetes mellitus (T2DM). Prior studies identifying a link between OSA and T2DM have excluded subjects with undiagnosed T2DM, and there is a lack of population-level data on the interaction between OSA and glycemic control among patients with diabetes. We assessed the relationship between OSA severity and T2DM prevalence and control in a large multinational population.METHODS: We performed a cross-sectional analysis of 6,616 participants in the European Sleep Apnea Cohort (ESADA) study, using multivariate regression analysis to assess T2DM prev…

AdultMalePulmonary and Respiratory MedicineAdolescentPolysomnographySettore MED/10 - Malattie Dell'Apparato RespiratorioCritical Care and Intensive Care MedicineSeverity of Illness IndexRegression AnalysiCohort Studiesintermittent hypoxia insulin resistance HbA1CYoung AdultSleep Apnea SyndromesSleep Apnea SyndromeRisk FactorsPrevalenceHumansProspective StudiesIsraelAgedGlycated HemoglobinAged 80 and overCross-Sectional StudieHemoglobin A GlycosylatedRisk FactorMiddle AgedEuropeProspective StudieCross-Sectional StudiesDiabetes Mellitus Type 2Regression AnalysisFemaleCohort StudieCardiology and Cardiovascular MedicineHuman
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Management of obstructive sleep apnea in Europe.

2011

Objectives: In Europe, the services provided for the investigation and management of obstructive sleep apnoea (OSA) varies from country to country. The aim of this questionnaire-based study was to investigate the current status of diagnostic pathways and therapeutic approaches applied in the treatment of OSA in Europe, qualification requirements of physicians involved in diagnosis and treatment of OSA, and reimbursement of these services. Methods: Two questionnaires were sent to 39 physicians in 22 countries in Europe. In order to standardize the responses, the questionnaire was accompanied by an example. Results: Sleep centers from 21 countries (38 physicians) participated. A broad consist…

medicine.medical_specialtyNeurologyCertificationInternationalityReferralmedicine.medical_treatmentPolysomnographyPolysomnographySettore MED/10 - Malattie Dell'Apparato RespiratorioSurveys and QuestionnairesPositive airway pressuremedicineHumansContinuous positive airway pressureIntensive care medicineReimbursementSleep Apnea ObstructivePublic health services sleep apnea sleep disordered breathing OSA management OSA therapy OSA reibursement OSA treatmentmedicine.diagnostic_testContinuous Positive Airway Pressurebusiness.industrySleep apneaProfessional PracticeMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREGeneral Medicinemedicine.diseaserespiratory tract diseasesObstructive sleep apneaEuropeHealth Care SurveysPublic health servicesSleep apnea Sleep disordered breathing OSA management OSA therapyOSA reimbursement OSA treatmentMedicineHuman medicinebusinessSleep medicine
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Nocturnal intermittent hypoxia predicts prevalent hypertension in the European Sleep Apnoea Database cohort study.

2014

Systemic hypertension is associated with obstructive sleep apnoea syndrome (OSAS) but the pathophysiological mechanisms are incompletely understood. A collaborative European network of 24 sleep centres established a European Sleep Apnoea Database to evaluate cardiovascular morbidity associated with OSAS.11 911 adults referred with suspected OSAS between March 2007 and September 2013 underwent overnight sleep studies, either cardiorespiratory polygraphy or polysomnography. We compared the predictive value of the apnoea–hypopnoea index (AHI) and 4% oxygen desaturation index (ODI) for prevalent hypertension, adjusting for relevant covariates including age, smoking, obesity, dyslipidaemia and d…

Pulmonary and Respiratory MedicineAdultMaleAdolescentDatabases FactualCross-sectional studyPolysomnographyPolysomnographySettore MED/10 - Malattie Dell'Apparato Respiratoriocomputer.software_genreta3111Sleep apnoea hypoxia hypertensionCohort StudiesYoung Adultstomatognathic systemmedicinePrevalenceHumansapnea hypopnea index oxygen desaturation index blood pressureHypoxiaAgedAged 80 and overSleep Apnea ObstructiveDatabasemedicine.diagnostic_testbusiness.industrySleep apneaIntermittent hypoxiaCardiorespiratory fitnessOdds ratioMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREMiddle Agedmedicine.diseaseObesitynervous system diseasesrespiratory tract diseasesEuropeCross-Sectional StudiesHypertensionFemalebusinesscomputerCohort studyThe European respiratory journal
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Chronic kidney disease in European patients with obstructive sleep apnea: the ESADA cohort study

2016

Abstract: The cross-sectional relationship of obstructive sleep apnea with moderate to severe chronic kidney disease, defined as an estimated glomerular filtration rate = 30) was found in 34% of subjects. The lowest nocturnal oxygen saturation was 81 +/- 10.2%. Chronic kidney disease prevalence in the whole sample was 8.7% or 6.1%, according to the Modification of Diet in Renal Disease or the Chronic Kidney Disease-Epidemiology Collaboration equations, respectively. Subjects with lower estimated glomerular filtration rate were older, more obese, more often female, had worse obstructive sleep apnea and more co-morbidities (P < 0.001, each). With both equations, independent predictors of esti…

MaleComorbidityBody Mass IndexCohort StudiesBehavioral Neuroscience0302 clinical medicineRisk FactorsPrevalenceobstructive sleep apneaAged 80 and overSex CharacteristicsSleep Apnea ObstructiveMedicine (all)Sleep apneaGeneral MedicineMiddle AgedEuropeHypertensionCardiologynephropathyepidemiologyFemaleGlomerular Filtration RateCohort studyAdultmedicine.medical_specialtyAdolescentPolysomnographyCognitive NeuroscienceRenal functionSettore MED/10 - Malattie Dell'Apparato Respiratoriota3111NephropathyYoung Adult03 medical and health sciencesInternal medicinemedicineHumansObesityRenal Insufficiency ChronicAgedHeart Failurehypoxiabusiness.industrymedicine.diseaseOxygenObstructive sleep apneaCross-Sectional Studies030228 respiratory systemHeart failurePhysical therapyHuman medicinebusinessBody mass index030217 neurology & neurosurgeryKidney diseaseJournal of Sleep Research
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