0000000000105415
AUTHOR
François Brunotte
Incomplete resolution of ST-segment elevation is associated with severe microvasculatory dysfunction evaluated by magnetic resonance imaging
International audience
Relation between the QRS fragmentation and parameters of no-reflow and infarct size in patients with myocardial infarction: a cardiac magnetic resonance study.
National audience
The study of myocardial viability after myocardial infarction: Valve and limitations of magnetic resonance imaging compared with myocardial scintigraphy.
International audience; Abstract: The aim of this study was to compare myocardial thickness measured by magnetic resonance imaging and quantified fixation of thallium. Twenty-one patients 61.2+/-11 years were investigated after myocardial infarction of the anterior wall in 8 cases, inferior in 10 cases, lateral in 2 cases and apical in one case. The mean angiographic ejection fraction was 46.5 +/- 19 %. Myocardial scintigraphy was performed after an exercise or pharmacological stress test and followed by a study of redistribution. The data was analysed by a quantitative method. Magnetic resonance imaging was performed with Vertical and horizontal long axis views in systole and diastole with…
Major Prognostic Impact of Persistent Microvascular Obstruction as Assessed by Contrast-Enhanced Cardiac Magnetic Resonance Imaging in the Setting of Reperfused Myocardial Infarction
International audience
Reduced brain N-acetyl-aspartate in frontal lobes suggests neuronal loss in patients with amyotrophic lateral sclerosis
International audience; Abstract: We performed proton magnetic resonance spectroscopy (IH-MRS) in three patients with amyotrophic lateral sclerosis (ALS) to evaluate the distribution and extent of cortical neuronal damage as demonstrated by decreased N-acetyl-aspartate (NAA) levels. We examined primary motor (precentral gyrus) and parietal neocortical (superior parietal gyrus) regions. ALS was defined with lower and upper motor neuron signs. Compared with matched healthy controls, ALS patients had a significant decrease in NAA levels in the primary motor cortex (p<0.001) compared with parietal regions and homologous regions in healthy controls. Two clinical applications can be extracted: fi…
PROSTATEANALYZER: GUI ALLOWING THE MANAGEMENT OF EXAMINATIONS OF PROSTATE CANCER
International audience; We propose a framework that comprises visualization and analysis for MR imaging of the prostate and a new storage system of clinical diagnoses in a single package. ProstateAnalyzer is such a network-based database system allowing the management of both MRI and spectroscopy data sets, and performing some basic mathematical operations to analyze a set of prostate images.
L'imagerie par résonance magnétique du myocarde avec des agents de contraste extracellulaires à base de gadolinium.
L'injection en bolus d'un agent de contraste extra-cellulaire contenant du gadolinium permet d'étudier le premier passage myocardique et le rehaussement tardif du myocarde chez les patients atteints de maladie coronarienne. Les applications les plus développées concernent l'évaluation de la viabilité. Celle-ci est réduite lorsque l'apparition du signal myocardique au premier passage est lente avec un rehaussement tardif transmural du signal myocardique. À partir des courbes de premier passage, il est possible d'étudier la perfusion myocardique et les effets des agents vasodilatateurs comme le dipyridamole ou l'adénosine. Le débit myocardique absolu peut aussi être calculé. Néanmoins, l'usag…
Breath-hold cine MR determination of left ventricular ejection fraction in post-myocardial infarction patients.
International audience
Incidence and Prognostic Impact of Persistent Microvascular Obstruction as Assessed by Cardiac Magnetic Resonance in the Setting of Non ST Segment Elevation Myocardial Infarction
International audience
Use of fuzzy techniques for the automatic identification of left ventricle contours from multi-slice short axis MR Imaging.
International audience
Fragmented Qrs Complex on a 12-Lead Ecg in Patients With Acute Myocardial Infarction: A MRI Study
International audience; The goal of this study is to investigate the relationship between a fragmented QRS complex (fQRS) and parameters of infarct size (IS) and no reflow assessed by cardiac magnetic resonance (CMR) in patients with acute myocardial infarction.
EFFECTS OF EXERCISE TRAINING AFTER MYOCARDIAL-INFARCTION ON MUSCULAR METABOLISM VALUE OF PHOSPHORUS 31 NMR-SPECTROSCOPY
International audience; Abstract: P 31 NMR spectroscopy is a recent technique which allows a non-invasive and direct analysis of oxidative metabolism and pH changes, an indicator of acidosis due to lactic acid accumulation in the skeletal muscles. The authors investigated oxidative muscular metabolism of the sural triceps in 10 patients after myocardial infarction by performing a study after the acute phase and repeating the study after a programme of physical training. At rest, there were no significant differences. On the other hand, for the same level of maximal effort, the depletion in phosphocreatinine (PCr) and the accumulation of inorganic phosphate (Pi) were significantly lower afte…
The best of non-invasive cardiac imaging in 1999.
International audience; The term non-invasive and non-echographic myocardial imaging is used to describe the advances in nuclear cardiology and magnetic resonance imaging underlying the most recent developments in investigating the myocardium. The value of new techniques such as rapid CT scan and cardiological applications of the synchroton are described. The main clinical applications of these techniques in the present and future are reviewed, especially with regards to ischaemic heart disease.
NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY OF EXCISED HUMAN HEARTS
International audience; Abstract: Background-Phosphorus nuclear magnetic resonance spectroscopy has been proposed as a method of studying the metabolism of the myocardium in patients. Little is known about P-31 nuclear magnetic resonance spectroscopy of diseased human hearts. Methods-Two donor hearts meeting the requirements for heart transplantation and 11 diseased hearts were removed during a transplantation procedure and were studied in a horizontal 2-35 T superconducting magnet. Spectra were obtained at 0-degrees-C about 30 minutes after the excision. The areas of the inorganic phosphate peak (Pi) and of the phosphocreatine peak (PCr) were summed and expressed as a ratio with respect to…