0000000000109652

AUTHOR

Dirk Hofmeister

showing 4 related works from this author

Quality-of-Life Priorities in Patients with Thyroid Cancer : a Multinational European Organisation for Research and Treatment of Cancer Phase I Study

2016

Item does not contain fulltext BACKGROUND: The objectives of this study were to determine quality of life (QoL) issues that are relevant to thyroid cancer patients cross-culturally, and to identify those with highest relevance to them in addition to the more general issues covered by the core European Organisation for Research and Treatment of Cancer QoL questionnaire (EORTC QLQ-C30). METHODS: A systematic literature search provided a list of potentially relevant QoL issues to supplement the core questionnaire EORTC QLQ-C30, which is widely used in research and in care and addresses QoL issues relevant to all groups of cancer patients. A panel of experts revised this list, and thyroid cance…

AdultCross-Cultural ComparisonMalemedicine.medical_specialtyPathologyInternationalityEndocrinology Diabetes and MetabolismAlternative medicine030209 endocrinology & metabolism03 medical and health sciences0302 clinical medicineEndocrinologyQuality of lifeAdenocarcinoma FollicularMedicineHumansIn patientThyroid NeoplasmsVoluntary Health AgenciesThyroid cancerFatigueAgedNeoplasm StagingAged 80 and overbusiness.industryCancerRehabilitation VocationalMiddle Agedmedicine.diseaseCross-cultural studiesCombined Modality TherapyCarcinoma PapillaryhumanitiesPhase i studyCarcinoma NeuroendocrineEuropeMultinational corporationThyroid Cancer Papillary030220 oncology & carcinogenesisFamily medicineCarcinoma MedullaryQuality of LifeFemaleSelf ReportbusinessRare cancers Radboud Institute for Health Sciences [Radboudumc 9]
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Measuring quality of life in patients with head and neck cancer: Update of the EORTC QLQ-H&N Module, Phase III

2014

Background The objective of this study was to pilot test an updated version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Module (EORTC QLQ-H&N60). Methods Patients with head and neck cancer were asked to complete a list of 60 head and neck cancer-specific items comprising the updated EORTC head and neck module and the core questionnaire EORTC QLQ-C30. Debriefing interviews were conducted to identify any irrelevant items and confusing or upsetting wording. Results Interviews were performed with 330 patients from 17 countries, representing different head and neck cancer sites and treatments. Forty-one of the 60 items were retain…

medicine.medical_specialtyPsychometricsbusiness.industryDebriefingHead and neck cancerHead necksocial sciencesmedicine.diseasehumanitiesSurgeryOtorhinolaryngologyQuality of lifePhysical therapyMedicineIn patientPilot testbusinessHead and neckHead & Neck
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Age- and sex-standardised prevalence rates of fatigue in a large hospital-based sample of cancer patients

2011

Background: The aim of this longitudinal study was to determine age- and sex-standardised prevalence rates of cancer-related fatigue in different groups of patients. Methods: This was a prospective study in a cohort of N=1494 cancer patients investigating fatigue at three time points t1–t3 (t1: admission to hospital, t2: discharge, t3: half a year after t1). Fatigue was measured with the Multidimensional Fatigue Inventory. Age- and sex-adjusted norms were derived from a representative community sample of N=2037, using a cutoff at the 75th percentile. Results: At admission to the hospital, 32% of the patients were classified as fatigued. At discharge, the overall prevalence rate was 40%, and…

Cancer Researchmedicine.medical_specialtyPediatricsprevalence studiesbusiness.industryEpidemiologyPrevalenceCancerSample (statistics)Hospital basedAge and sexmedicine.diseaseprospective studiesOncologySex factorsNeoplasmsPhysical therapymedicineHumansfatigueProspective cohort studybusinessmental healthBritish Journal of Cancer
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International validation of the revised European Organisation for Research and treatment of cancer head and neck cancer module, the EORTC QLQ-HN43

2019

Background: We validated the new European Organisation for Research and Treatment of Cancer Quality of Life Head and Neck Module (EORTC QLQ-HN43). Methods: We enrolled 812 patients with head and neck cancer from 18 countries. Group 1 completed the questionnaire before therapy, and 3 and 6 months later. In group 2 (survivors), we determined test–retest reliability using intraclass correlation coefficients (ICC). Internal consistency was assessed using Cronbach's Alpha, the scale structure with confirmatory factor analysis, and discriminant validity with known-group comparisons. Results: Cronbach's alpha was >0.70 in 10 of the 12 multi-item scales. All standardized factor loadings exceeded…

Multimodal therapiesQuality of lifeMalemedicine.medical_specialtySDG 16 - PeacePsychometricsIntraclass correlationMedizinSensitivity and Specificity03 medical and health sciences0302 clinical medicineCronbach's alphaQuality of lifeSurveys and QuestionnairesValidationOutcome Assessment Health CaremedicineHumansProspective Studies030212 general & internal medicineHead and neck cancerReliability (statistics)AgedAged 80 and overbusiness.industryHead and neck cancerSDG 16 - Peace Justice and Strong InstitutionsDiscriminant validityReproducibility of ResultsCancerMiddle Agedmedicine.diseaseCombined Modality Therapy/dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutionsConfirmatory factor analysishumanitiesJustice and Strong Institutions3. Good healthEuropeChemoradiationOtorhinolaryngologyHead and Neck Neoplasms030220 oncology & carcinogenesisQuality of LifePhysical therapyFemalebusinessHead and Neck
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