0000000000112761
AUTHOR
Roland Dumas
N-ACETYL-ASPARTATE ABNORMALITIES IN INTERNAL-TEMPORAL EPILEPTICUS FOCUS USING PROTON MAGNETIC-RESONANCE SPECTROSCOPY
International audience; Abstract: The aim of this study was to characterize the neurochemical abnormalities related to N-acetyl-aspartate which is a neuronal marker, within an epilepticus focus located in the internal-temporal area, using proton magnetic resonance spectroscopy, Eleven patients,with a mono-hippocampal epilepticus focus on clinical and per-critical electroencephalographical criteria, were matched with II controls by age, sex and laterality. Proton spectroscopy of a volume of 8 cm(3) was performed within the ipsilateral and the contralateral internal-temporal area and within the 2 hippocampus of controls. Volumetry of the ipsilateral and the contralateral hippocampus and of th…
PRELIMINARY-OBSERVATIONS OF METABOLIC CHARACTERIZATION OF BILATERAL TEMPORAL EPILEPTIC FOCUS, USING PROTON MAGNETIC-RESONANCE SPECTROSCOPY - 3 CASES
International audience; Abstract: The authors report the case of 3 patients with bilateral temporal lobe epilepsy demonstrated by EEG and sphenoidal electrodes. Two out of the 3 patients presented with childhood febrile convulsions. Their neurological and mental examination was normal. EEG showed spikes within the anterior part of the 2 temporal lobes. CT scan and MRI showed no atrophic lesion within the 2 temporal lobes. Proton magnetic resonance spectroscopy, performed within a cube of 8 cube-centimetres localized in the anterior part of the 2 temporal lobes showed a significant decrease of N-acetyl-aspartate in the 2 temporal lobes of the 3 cases, compared with controls matched with age,…