0000000000113768

AUTHOR

Volkmar Mueller

showing 3 related works from this author

149P Predicting prognosis of breast cancer patients with brain metastases in the BMBC registry: Comparison of three different prognostic scores

2020

Oncologymedicine.medical_specialtyBreast cancerOncologybusiness.industryInternal medicineMedicineHematologybusinessmedicine.diseaseAnnals of Oncology
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A randomized, open-label, multicentre, phase IV study evaluating palbociclib plus endocrine treatment versus a chemotherapy based treatment strategy …

2017

TPS1115 Background: Although endocrine based therapy is recommended as first-line treatment in metastatic breast cancer (MBC) in patients with an HER2-/HR+ tumour up to 50% of the patients receive chemotherapy. Palbociclib (P) a CDK4/6 inhibitor improves PFS by 42% in endocrine sensitive and resistant HER2-/HR+ MBC when added to an endocrine therapy (ET). Patients included in clinical trials are often criticised not to be representative for real world breast cancer patients. Methods: Patients with first-line HER2-/HR+ MBC who are candidate for mono-chemotherapy will be eligible to be randomised 1:1 to receive either P plus ET per label or mono-chemotherapy per investigator´s choice with or…

GynecologyOncologyCancer Researchmedicine.medical_specialtyChemotherapybusiness.industrymedicine.medical_treatmentHER2 negativePalbociclibmedicine.diseaseMetastatic breast cancerOncologyHormone receptorInternal medicinemedicineEndocrine systemIn patientOpen labelbusinessJournal of Clinical Oncology
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Brain Metastases in Breast Cancer Network Germany (BMBC, GBG 79): Treatment patterns and clinical outcome of more than 1000 patients with brain metas…

2016

2070Background: In order to improve knowledge about treatment and outcome of breast cancer patients with brain metastases (BM) we initiated the registry Brain Metastases in Breast Cancer Network Ge...

0301 basic medicineOncologyCancer Researchmedicine.medical_specialtybusiness.industrymedicine.diseaseOutcome (game theory)03 medical and health sciences030104 developmental biology0302 clinical medicineBreast cancerOncology030220 oncology & carcinogenesisInternal medicinemedicineskin and connective tissue diseasesbusinessJournal of Clinical Oncology
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