Editorial: 150 years of the Periodic Table of Chemical Elements

Production and Radiochemical Separation of the Auger Electron Emitter140Nd

Among the Auger electron emitters, the radiolanthanide 140Nd has some unique nuclear properties with potential for endoradiotherapeutic applications. In the present study, 140Nd was produced via the 140Ce(3He,3n) nuclear process at the FZ Julich CV28 cyclotron, irradiating CeO2 with 3He particles of 36 MeV primary energy. Yields of about 5 MBq 140Nd per microAh were experimentally obtained. Batch yields of > 100 MBq 140Nd were reached. 140Nd was separated in 75 +/- 5% radiochemical yield using a two-step process, first by extracting the bulk of the target material according to a Ce(IV)/Nd(III) separation, then by final ion exchange purification.

A no-carrier-added 72Se/72As radionuclide generator based on distillation

Abstract Arsenic-72 is a positron emitting isotope with promising properties for syntheses of 72As-labelled radiopharmaceuticals for future application in positron emission tomography. This work describes the radiochemical separation of no-carrier-added 72Se from cyclotron irradiated germanium targets and the development of a 72Se/72As radionuclide generator, avoiding the addition of any selenium carrier. Using a vertical quartz tube device, no-carrier-added 72As is nearly quantitatively released from various chloride salt solutions containing 72Se within 10 min at a temperature of 100 °C in an HCl gas flow. The kinetics of the 72Se/72As isotope generator has been studied in relation to tem…

A no-carrier-added72Se/72As radionuclide generator based on solid phase extraction

Summary72As-labelled radiopharmaceuticals could be a valuable resource for Positron Emission Tomography (PET). In particular, the long half-life of72As (T1/2= 26 h) facilitates the observation of long-term physiological or metabolic processes, such as the enrichment and distribution of antibodies in tumor tissue. This work describes the primary radiochemical separation of no-carrier-added (nca)72Se from cyclotron irradiated germanium targets and the development of a polystyrene type solid-phase extraction based72Se/72As radionuclide generator, avoiding the addition of any selenium carrier. The irradiated germanium target is dissolved in HFconcand selenium is reduced with hydrazine dihydroch…