0000000000114033

AUTHOR

M. Teresa Arnedo

showing 2 related works from this author

Effects of chronic administration with high doses of testosterone propionate on behavioral and physiological parameters in mice with differing basal …

2003

The effects of testosterone propionate, an anabolic-androgenic steroid, on the behavior displayed during a social encounter by gonadally intact male mice were investigated. Animals were distributed into three groups according to their attack latency in a pre-screening test (high-, moderate-, and low-attacking mice) and each group received weekly injections of 60 or 120 mg/kg of testosterone or sesame oil for 10 weeks. Behavioral tests were then carried out. Afterwards, organs were weighed and blood samples collected in order to obtain hormonal data. Treatment had a differential impact on attack in the three groups of animals. Only the high-attacking testosterone-treated mice showed lower to…

Testosterone propionatemedicine.medical_specialtyAnabolismmedicine.medical_treatmentPoison controlPeripheralSteroidchemistry.chemical_compoundEndocrinologyArts and Humanities (miscellaneous)chemistryInternal medicineDevelopmental and Educational PsychologymedicineHigh dosesSocial encounterPsychologyGeneral PsychologyHormoneAggressive Behavior
researchProduct

Similar rewarding effects of testosterone in mice rated as short and long attack latency individuals.

2002

An attempt was made to confirm and extend the findings of an earlier study on the rewarding properties of testosterone in male mice using conditioned place preference (CPP). Previous results had only partially demonstrated such an effect because the reinforcement depended on environmental cues such as the colour of the compartment. High individual variability was evident, suggesting that basal levels of aggressiveness may modulate such effects. Animals were pre-screened for aggressive behaviour and allocated to short and long attack latency (SAL and LAL) categories. Five days later the CPP procedure started. This involved pre-conditioning tests, conditioning and post-conditioning tests. SAL…

Malemedicine.medical_specialtyInjections SubcutaneousMedicine (miscellaneous)Male miceDevelopmental psychologyBasal (phylogenetics)MiceRandom AllocationRewardInternal medicineTestosterone treatmentConditioning PsychologicalmedicineAnimalsTestosteroneLatency (engineering)ReinforcementPharmacologyBehavior AnimalTestosterone (patch)Conditioned place preferenceAggressionPsychiatry and Mental healthEndocrinologyConditioningPsychologyReinforcement PsychologyAddiction biology
researchProduct