0000000000114268
AUTHOR
W. Rückert
showing 2 related works from this author
Metabolismus der Cyclodien-Insecticide Alodan� und Endosulfan (=Thiodan�) in Fliegen
1972
Versuche zum Metabolismus verschiedener Cyclodien-Insecticide in der Hausfliege (Musca domestica) ergaben, das nicht, wie bisher angenommen, das Endosulfan-Lacton als Endprodukt der Umwandlung anzusehen ist, sondern das der oxydative Abbau weiterschreitet. Als weiteres Glied in der Kette der hoher oxydierten Verbindungen konnte indirekt uber Hydrolyse und Veratherung gas-chromatographisch das Hydroxy-Endosulfan-Lacton nachgewiesen werden.
Abbau und Toxizität von Hexachlorbicyclo [2.2.1]-hept-5-en- Derivaten (Cyclodien-Insektizide) / Structural Aspects of Biological Conversion and Toxic…
1973
The aspects of molecular-structure and biological conversion have been studied for 12 derivatives of the endosulfan ether 1 [4, 5, 6, 7, 8, 8- hexachloro- 1, 3, 3a, 4, 7, 7a- hexahydro- 4, 7-methanoisobenzofuran]. Adults of a normal house-fly strain (Musca domestica) have been used in the assay. Derivatives of 1 monosubstituted in position I are found to be converted substantially faster than products disubstituted in position I and 3, respectively. Metabolism is inhibited for all compounds studied after application of piperonyl butoxide as a synergist. Besides proving that on oxidative metabolism has to be discussed and in fact could be proved for some derivatives, the intrinsic toxicity o…