0000000000114595
AUTHOR
T. Göen
Speichel als Matrix für das Humanbiomonitoring in der Arbeits- und Umweltmedizin [Biomonitoring Methods in German Language, 2015]
Saliva as a matrix for human biomonitoring in occupational and environmental medicine Purpose: Human biomonitoring (HBM) implies the assessment of internal exposure to hazardous substances by measuring the substances, their metabolites or reaction products, as well as effect parameters in human body fluids. Along with blood, plasma and urine, saliva is of increasing interest as an alternative matrix for HBM. Methods: This paper reviews studies that measure salivary background levels of hazardous substances, elevated levels after environmental or occupational exposure, as well as references which deal with physiological and toxicokinetic behaviour of saliva and salivary parameters, respectiv…