0000000000114793

AUTHOR

Birgit Völlm

S08-01 - Cochrane Reviews of Pharmacological and Psychological Interventions for Antisocial Personality Disorder (ASPD)

IntroductionASPD has a prevalence of 2-3% in the general population but rates in prison have been reported as 50% to 75%. ASPD is associated with significant psychiatric and medical comorbidity, high offending rates, poor psychosocial adaptation and premature death. Outcomes are poor. There is little consensus regarding the most effective intervention for the condition.Aims and objectivesTo conduct systematic literature reviews to identify randomised controlled trials for either pharmacological or psychological interventions for ASPD.MethodsSystematic literature reviews (Cochrane reviews).ResultsFor the review on psychological interventions only 11 studies could be included with a total of …

research product

Pharmacological interventions for paranoid personality disorder

Reason for withdrawal from publication Authors have made no progress with this protocol in over three years due to difficulties with identifying potentially suitable studies. The protocol has been withdrawn. To view the published versions of this article, please click the 'Other versions' tab.

research product

Short-term Psychological Interventions for Bordeline Personality Disorder–What Works?

IntroductionBorderline personality disorder (BPD) is a common and disabling personality disorder associated with difficulties in controlling emotions and impulses, self-injury, feelings of emptiness and abandonment. It is associated with problems in many areas of life, most notably relationships. Psychotherapy is the first-line treatment for people with borderline personality disorder widely used; however, the evidence is not thoroughly investigated. In addition, several specific short-term interventions have been developed during the last decades.ObjectivesWe are currently updating this cochrane collaboration review on psychological interventions for BPD. First findings on the up-to-date e…

research product

Psychological interventions for obsessive-compulsive personality disorder

Reason for withdrawal from publication Authors have made no progress with this protocol in over three years due to difficulties with identifying potentially suitable studies. The protocol has been withdrawn. To view the published versions of this article, please click the 'Other versions' tab.

research product

Is pharmacotherapy useful for treating personality disorders?

Personality disorders are characterized by enduring maladaptive patterns of behavior, cognition, and inner experience exhibited across many contexts and deviating from those accepted by the individ...

research product

Pharmacological interventions for schizoid personality disorder

Reason for withdrawal from publication Authors have made no progress with this protocol in over three years due to difficulties with identifying potentially suitable studies. The protocol has been withdrawn. To view the published versions of this article, please click the 'Other versions' tab.

research product

Pharmacological interventions for avoidant personality disorder

Reason for withdrawal from publication Authors have made no progress with this protocol in over two years due to difficulties with identifying potentially suitable studies. The protocol has been withdrawn. To view the published versions of this article, please click the 'Other versions' tab.

research product

Pharmacological interventions for schizotypal personality disorder

Reason for withdrawal from publication Authors have made no progress with this protocol in over a year due to difficulties with identifying potentially suitable studies. The protocol has been withdrawn. To view the published versions of this article, please click the 'Other versions' tab.

research product

AS14-02 - Common and distinct treatment elements in psychotherapies for borderline personality disorder

Introduction Borderline personality disorder (BPD) is defined as “a pervasive pattern of instability of interpersonal relationships, self-image, affects, and marked impulsivity” (DSM-IV-TR; APA, 2000). These very characteristics make it difficult to establish firm therapeutic relationships and keep patients in treatment. In recent decades, a number of new psychotherapeutic approaches have been developed in order to meet these specific challenges and demands. To date, there is evidence of efficacy for various treatments, as data of a recent systematic review and meta-analysis of our working group indicate. Objectives To give an overview of all psychotherapeutic treatments investigated in ran…

research product

Pharmacotherapy of Borderline Personality Disorder: A Metaanalysis of Randomised Controlled Trials

Background:In Borderline Personality Disorder (BPD), pharmacotherapy is used for the treatment of specific BPD pathology facets, such as cognitive-perceptual, affective, or impulsivity symptoms. Due to the polymorphic phenomenology of the disorder, different classes of drugs are used, e.g., antipsychotics, antidepressants, or mood stabilizers.Aims:To evaluate the up-to-date evidence of drug treatment efficacy for BPD.Method:A systematic review and metaanalysis of randomised controlled trials was done. All randomised comparisons of drug vs. placebo, drug vs. drug, or drug vs. a combination of drugs in adult BPD patients were eligible for inclusion. Outcomes comprised BPD core pathology as de…

research product

Systematic review of psychotherapeutic treatments for “minor” personality disorders

IntroductionAmong personality disorders (PDs), antisocial and borderline personality disorder are well-studied. However, the remaining PDs (in the following called “minor PDs”) pose major problems in everyday-health care settings. People affected often present with additional axis-l disorders such as substance-related, mood or anxiety disorders, and are among those most difficult to treat.ObjectivesTo systematically review the current evidence of psychotherapeutic treatments for “minor” personality disordersMethodsIn the context of Cochrane Collaboration reviews for Cluster A, B and C PDs, exhaustive literature searches were done to identify the current RCT evidence for PD treatments. The e…

research product

Do Mood Stabilizers Help in Borderline Personality Disorder?

BackgroundDespite the relatively weak evidence base, individuals with borderline personality disorder are often treated with pharmacological interventions. Amongst the drugs, which have shown most promise, are mood stabilizers, which were one of the two drug classes with the most beneficial effects in a previous cochrane review though the robustness of findings was described as low (Stoffers et al., 2010). Here we present data on the latest evidence for mood stabilizers based on an updated cochrane review currently underway.MethodsA systematic review and meta-analysis of randomized controlled trials was conducted. All randomized comparisons of drug vs. placebo, drug vs. drug, or drug vs. a …

research product

Psychological interventions for people with narcissistic personality disorder

Reason for withdrawal from publication Authors have made no progress with this protocol in over a year due to difficulties with identifying potentially suitable studies. The protocol has been withdrawn.

research product

Pharmacological interventions for people with histrionic personality disorder

Reason for withdrawal from publication Authors have made no progress with this protocol in over a year due to difficulties with identifying potentially suitable studies. The protocol has been withdrawn. To view the published versions of this article, please click the 'Other versions' tab.

research product

Psychological interventions for people with histrionic personality disorder

Reason for withdrawal from publication Authors have made no progress with this protocol in over a year due to difficulties with identifying potentially suitable studies. The protocol has been withdrawn. To view the published versions of this article, please click the 'Other versions' tab.

research product

Are Treatment Gains Maintained? Long-term Psychological Interventions for Bordeline Personality Disorder

IntroductionMany new approaches have been developed to treat borderline personality disorder (BPD) by means of psychotherapy. Though there is a clear research trend towards short-interventions, the evidence from randomised controlled trials (RCT) on longer-term programmes still accumulates. On the one hand, well-established treatments like Dialectical Behavior Therapy (DBT) or Mentalisation-Based Treatment (MBT) are now subject to real-world effectiveness studies; on the other hand, new dynamic approaches have been studied, lasting longer than 6 months.ObjectivesWe are currently updating the cochrane Collaboration review on psychological interventions for BPD. First findings on the effects …

research product

Pharmacological interventions for people with narcissistic personality disorder

Reason for withdrawal from publication Authors have made no progress with this protocol in over two years due to difficulties with identifying potentially suitable studies. The protocol has been withdrawn. To view the published versions of this article, please click the 'Other versions' tab.

research product

Effectiveness of Antipsychotic Medication in the Treatment of BPD

IntroductionThough prescription is off-lable, “atypical” or “second-generation” antipsychotics (SGAs) are prevalently given to borderline personality disorder (BPD) patients. They have also been the focus of research on pharmacological agents in BPD in recent years, as the previous version of the relating cochrane systematic review shows.ObjectivesWe are currently updating this cochrane systematic review on pharmacological interventions for BPD. First findings on the up-to-date evidence relating to SGAs will be presented.MethodsWe conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) according to cochrane collaboration standards. Any randomized comparisons o…

research product