0000000000116180

AUTHOR

Naír Rodríguez-hornedo

showing 1 related works from this author

Exploring Bioequivalence of Dexketoprofen Trometamol Drug Products with the Gastrointestinal Simulator (GIS) and Precipitation Pathways Analyses

2019

The present work aimed to explain the differences in oral performance in fasted humans who were categorized into groups based on the three different drug product formulations of dexketoprofen trometamol (DKT) salt&mdash

liquid–liquid phase separationSALT DISPROPORTIONATIONgastrointestinal absorptionSodiumlcsh:RS1-441Pharmaceutical ScienceExcipientchemistry.chemical_elementSalt (chemistry)Hydrochloric acidSOLUBILITYCalciumBioequivalenceArticlelcsh:Pharmacy and materia medicachemistry.chemical_compoundFLUIDSEMAoral absorptionABSORPTIONmedicinePharmacology & PharmacySUPERSATURATED SOLUTIONSdexketoprofenSimulationchemistry.chemical_classificationScience & TechnologyChemistryliquid-liquid phase separationPhosphateDexketoprofenSIMILARITIESgastrointestinal simulatorin vitro dissolutionIN-VITRO DISSOLUTIONLife Sciences & BiomedicineVIVO DISSOLUTIONMETHODOLOGYmicroscopy imagingmedicine.drugPharmaceutics
researchProduct