0000000000116694

AUTHOR

A. Mika-gruettner

showing 5 related works from this author

Electrophysiological brainstem testing in the diagnosis of reversible brainstem ischemia.

2002

The aim of this study was to evaluate the sensitivity of multimodal electrophysiological brainstem testing in the diagnosis of clinically suspected reversible ischemic deficits of the brainstem compared with diffusion weighted MR imaging. We investigated 158 consecutive patients presenting with signs of acute brainstem dysfunction. Serial electrophysiological brainstem tests including masseter reflex, blink reflex, masseter inhibitory reflex, AEP, MEP, EOG and the oculoauricular phenomenon were applied. In 14 of the 158 patients neurological deficits resolved in less than 24 hours, which was suggestive of a transitory ischemic attack (TIA), 19 patients had brainstem signs for more than 24 h…

AdultMalemedicine.medical_specialtyPathologyNeurologyIschemiaSensitivity and SpecificityInternal medicineotorhinolaryngologic diseasesmedicineHumansCorneal reflexProspective StudiesEvoked potentialAgedAged 80 and overmedicine.diagnostic_testBlinkingbusiness.industryElectromyographyMagnetic resonance imagingMiddle Agedmedicine.diseaseEvoked Potentials MotorMagnetic Resonance ImagingElectrooculographyNeurologyIschemic Attack TransientCardiologyReflexEvoked Potentials AuditoryFemaleNeurology (clinical)BrainstembusinessJaw jerk reflexJournal of neurology
researchProduct

A new method to investigate brain stem structural-functional correlations using digital post-processing MRI - reliability in ischemic internuclear op…

2001

We investigated the reliability of a new digital post-processing magnetic resonance imaging (MRI) technique in ischemic brain stem lesions to identify relations of the lesion to anatomical brain stem structures. The target was a medial longitudinal fasciculus (MLF) lesion, which was evident from ipsilateral internuclear ophthalmoplegia (INO). Sixteen patients with acute unilateral INO and an isolated acute brain stem lesion in T2- and EPI-diffusion weighted MRI within 2 days after the onset of symptoms were studied. The MRI slice direction was parallel and perpendicular to a slice selection of a stereotactic anatomical atlas. The individual slices were normalized and projected in the digita…

AdultMalePathologymedicine.medical_specialtyInternuclear ophthalmoplegiaAnatomical structuresLesionImage Processing Computer-AssistedmedicineHumansAgedBrain MappingOphthalmoplegiamedicine.diagnostic_testbusiness.industryReproducibility of ResultsEye movementMagnetic resonance imagingAnatomyMiddle AgedMedial longitudinal fasciculusmedicine.diseaseMagnetic Resonance ImagingElectrooculographyElectrophysiologyNeurologySlice selectionFemaleNeurology (clinical)medicine.symptombusinessBrain StemEuropean Journal of Neurology
researchProduct

Diffusionsgewichtetes MRT bei vertebrobasil�ren Isch�mien

2004

The aim of this study was to evaluate the applicability, sensitivity, and predictive power of diffusion-weighted MR imaging (DWI) in the diagnosis of vertebrobasilar infarction. From 1997 to 2002, we prospectively recruited 268 patients with acute signs and symptoms suspective of vertebrobasilar ischemia. The patients underwent biplanar EPI-T2 and EPI DWI within 24 h after onset of symptoms and high-resolution MRI as a control within 7 days. One hundred twenty-one patients had additional CT scanning. The DWI revealed acute vertebrobasilar infarction in 71.0%. The mean time exposure of DWI was 8 min and thus no more than that of CT imaging. It showed significantly more acute lesions than CT …

medicine.medical_specialtybusiness.industryInfarctionSigns and symptomsGeneral Medicinemedicine.diseaseMr imagingAcute ischemiaSurgeryPsychiatry and Mental healthNeurologyVertebrobasilar ischemiaMedicineCerebellar infarctionIn patientcardiovascular diseasesNeurology (clinical)RadiologyCt imagingbusinessDer Nervenarzt
researchProduct

Diffusion weighted magnetic resonance imaging in the diagnosis of reversible ischaemic deficits of the brainstem

2002

Objectives: To evaluate the sensitivity of diffusion weighted magnetic resonance imaging (MRI) for the diagnosis of clinically suspected reversible ischaemic deficits of the brainstem. Methods: A total of 158 consecutive patients presenting with acute signs of brainstem dysfunction were investigated using EPI diffusion weighted MRI within 24 hours of the onset of symptoms. High resolution T1 and T2 weighted imaging was performed as a follow up after a median of six days Results: Fourteen of the 158 patients had a complete clinical recovery within 24 hours (transitory ischaemic attack (TIA)), and 19 patients recovered in less than one week (prolonged reversible neurological deficit (RIND)). …

AdultMalePapermedicine.medical_specialtyIschemiaSensitivity and SpecificityCentral nervous system diseaseDiagnosis DifferentialRisk FactorsInternal medicinemedicineHumansProspective StudiesStrokeAgedAged 80 and overNeurologic ExaminationVascular diseasebusiness.industryMiddle Agedmedicine.diseaseequipment and suppliesMagnetic Resonance ImagingDiffusion-Weighted Magnetic Resonance ImagingSurgeryStrokePsychiatry and Mental healthEditorial CommentaryIschemic Attack TransientAcute DiseaseCardiologySurgeryFemaleNeurology (clinical)BrainstemT2 weightedbusinesshuman activitiesDiffusion MRIBrain Stem
researchProduct

Topodiagnostic value of blink reflex R1 changes: a digital postprocessing MRI correlation study.

2001

The aim of the study was to investigate the relation of the blink reflex R1 arc to known anatomical brainstem structures. Acute vascular brainstem lesions as identified by magnetic resonance imaging (MRI) of patients with isolated R1 pathology were superimposed into a stereotactic anatomical atlas using a new method of digital postprocessing. Isolated acute brainstem lesions were documented by diffusion-weighted MRI in 12 of 24 patients with unilateral R1 pathology. The lesions were located in the ipsilateral mid- to lower pons. In three patients only, the lesion had partial contact with the principal sensory nucleus of the trigeminal nerve (PSN) on at least one level. In two patients, the …

AdultMaleBrain Stem InfarctionsPhysiologyCellular and Molecular NeurosciencePhysiology (medical)medicineImage Processing Computer-AssistedHumansCorneal reflexAgedTrigeminal nerveAged 80 and overmedicine.diagnostic_testBlinkingReflex arcSpinal trigeminal nucleusMagnetic resonance imagingAnatomyMiddle AgedMedial longitudinal fasciculusMagnetic Resonance ImagingPonsElectric Stimulationmedicine.anatomical_structureFemaleNeurology (clinical)BrainstemPsychologyBrain StemMusclenerve
researchProduct