0000000000117014

AUTHOR

Juha Muilu

0000-0002-1034-5171

showing 1 related works from this author

A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol

2012

Serum lipid levels have been associated with cardiovascular diseases, metabolic syndrome and type II diabetes (Kannel et al., 1961; Miller & Miller, 1975; Pilia et al., 2006). Variation in lipids levels is highly influenced by heritable factors (Friedlander et al., 1997) and 95 loci have already been associated with levels of high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol, triglycerides (TG) and total cholesterol (TC) in numerous study samples and replicated in various populations using genome-wide approaches (Aulchenko et al., 2008; Kathiresan et al., 2008; Kooner et al., 2008; Teslovich et al., 2010; Willer et al., 2008). However, the genetic associa…

AdultNetherlands Twin Register (NTR)Candidate genegenetiikkaPopulationkolesteroliMonozygotic twinLocus (genetics)Genome-wide association studyBiologyPolymorphism Single NucleotideArticle03 medical and health sciences0302 clinical medicineGenetic variation/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_HumansAlleleGene–environment interactioneducationAllelesGenetics (clinical)Aged030304 developmental biologyAged 80 and overGenetics0303 health scienceseducation.field_of_studyperinnöllisyystiedeCholesterol HDLGTPase-Activating ProteinsObstetrics and Gynecologyta3141Twins MonozygoticMiddle AgedIntrons3. Good healthGenetic LociPediatrics Perinatology and Child HealthFemaleGene-Environment InteractionApolipoprotein A-II030217 neurology & neurosurgeryGenome-Wide Association Study
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